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6533b855fe1ef96bd12b139d

RESEARCH PRODUCT

DNA methylation patterns in newborns exposed to tobacco in utero

Gustavo F. BayónRedon JosepJosep RedonAgustín F. FernándezMario F. FragaConsuelo Garcia-vicentEmpar LurbeEmpar LurbeCarmen IvorraCarmen IvorraF. Javier ChavesF. Javier Chaves

subject

AdultEpigenomicsMothersPhysiologyBiologyGeneral Biochemistry Genetics and Molecular BiologyEpigenesis GeneticAdrenomedullinYoung Adultchemistry.chemical_compoundPregnancyRisk FactorsTobaccoCluster AnalysisHumansAdrenomedullin geneEpigeneticsNewbornsEpigenomicsMedicine(all)ImmunoassayDNA methylationBiochemistry Genetics and Molecular Biology(all)ResearchInfant NewbornGeneral MedicineMethylationFetal BloodGene Expression RegulationchemistryCpG siteMaternal ExposureIn uteroImmunologyDNA methylationCpG IslandsFemaleTobacco Smoke PollutionCotinineGenome-Wide Association StudyDNA hypomethylation

description

[Background] Maternal smoking during pregnancy is a major risk factor for adverse health outcomes. The main objective of the study was to assess the impact of in utero tobacco exposure on DNA methylation in children born at term with appropriate weight at birth.

yearjournalcountryeditionlanguage
2015-01-27Journal of Translational Medicine
https://doi.org/10.1186/s12967-015-0384-5
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