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RESEARCH PRODUCT
Human exceptional longevity: transcriptome from centenarians is distinct from septuagenarians and reveals a role of Bcl-xL in successful aging.
Ander MatheuAlessandra ErrigoJuan GambiniIdoia GarciaConsuelo BorrásJose ViñaMónica De La FuenteLeocadio Rodríguez-mañasPaula SanchisKheira M. AbdelazizMarta InglesEva SernaNuria FlamesCarla Lloret-fernandezÁNgel Belenguer-vareaAna BarettinoJuan A. AvellanaGianni Pessubject
0301 basic medicineAgingFAS ligandmedia_common.quotation_subjectBiologíaLongevitybcl-X ProteinBcl-xLPeripheral blood mononuclear cellFas ligandTranscriptome03 medical and health sciences0302 clinical medicineAnimalsHumansBcl-2RNA MessengerCaenorhabditis elegansmedia_commonAgedGeneticsAged 80 and overSuccessful agingbiologyLongevityapoptosisCell BiologyGenéticaUp-RegulationRNA; apoptosis030104 developmental biologyhealthy agingGene Expression RegulationApoptosis030220 oncology & carcinogenesisbiology.proteinRNATranscriptomeLeukocyte chemotaxisResearch Paperdescription
24 páginas, 7 figuras. Borras C, et al. Human exceptional longevity: transcriptome from centenarians is distinct from septuagenarians and reveals a role of Bcl-xL in successful aging. Aging (Albany NY). 2016 Oct 28;8(12):3185-3208. doi: 10.18632/aging.101078.
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2016-10-28 |