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RESEARCH PRODUCT
Evaluation of gastric intramucosal pH during and after pediatric cardiac surgery.
Franz X. SchmidRalph G. HuthChristoph KampmannBalthasar EberleDietmar SchranzIris BrandeyC. F. Wippermannsubject
Pulmonary and Respiratory MedicineHeart Defects CongenitalMalemedicine.medical_specialtyAdolescentmedicine.medical_treatmentSensitivity and Specificitylaw.inventionFontan procedurePostoperative ComplicationslawIntensive Care Units NeonatalMonitoring IntraoperativemedicineCardiopulmonary bypassHumansChildSurvival ratebusiness.industryStomachOrgan dysfunctionCentral venous pressureInfant NewbornInfantGeneral MedicineHydrogen-Ion ConcentrationIntensive care unitSurgeryCardiac surgerySurvival Ratemedicine.anatomical_structureGastric MucosaAnesthesiaChild PreschoolSurgeryFemalemedicine.symptomMorbidityCardiology and Cardiovascular Medicinebusinessdescription
Objectives: In adult patients, intramucosal pH (pHi) has been advocated to detect postoperative complications. The purpose of our study was to evaluate this technique in pediatric patients during and after cardiac surgery. Methods: Thirty-five infants (age: 5 days to 15 years, median 1.8 years; and weight: 3.2‐32 kg, median 9.8 kg) were studied. pHi was measured before cardiopulmonary bypass (CPB), after 30 min of CPB, prior to weaning off CPB, at intensive care unit arrival, and 6, 12, 24, 48 and 72 h after surgery. Results: There were no complications related to the tonometer. A pathologically low pHiB 7.32 was found during surgery in less than 17%, at intensive care unit arrival in 83% and after 48 h in 18%. pHi values were lower (PB0.05) at intensive care unit arrival (7.2590.08) and after 6 h (7.289 0.09) than afterwards. pHi correlated with arterial pH (r0.66), central‐peripheral temperature difference (r0.36), lactate (r 0.32) and central venous pressure (r 0.21). Patients after a Fontan procedure had postoperatively a lower pHi than after other operations (PB 0.05). None of the patients died or developed organ failure. Six patients had signs of organ dysfunction. Their pHi (median 7.23, range 7.14‐7.28) could not differentiate them from the other patients. Conclusions: With current equipment, tonometry cannot be recommended for the management of pediatric patients after cardiac surgery. However, as a semi-invasive method tonometry deserves further evaluation. © 1997 Elsevier Science B.V.
year | journal | country | edition | language |
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1997-08-01 | European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery |