6533b857fe1ef96bd12b4f4f

RESEARCH PRODUCT

The three-dimensional structure of Drosophila melanogaster (6–4) photolyase at room temperature

Eriko NangoWeixiao Yuan WahlgrenMarius SchmidtSwagatha GhoshSo IwataAmke NimmrichAndrea CelliniSebastian WestenhoffShigeki OwadaJoachim KübelJanne A. IhalainenLéocadie HenryElin ClaessonSuraj PandeyValentyna KuznetsovaLeticia CastillonHeikki TakalaEmina A. Stojković

subject

MECHANISMMaterials scienceAbsorption spectroscopyDNA repairfotobiologia02 engineering and technologyCrystal structureREPAIR ACTIVITY03 medical and health sciencesCOLI DNA PHOTOLYASEX-RAY-DIFFRACTIONCryptochromeStructural BiologyAnimalsserial crystallographyCRYSTAL-STRUCTURECRYPTOCHROMEPhotolyaseSERIAL FEMTOSECOND CRYSTALLOGRAPHY030304 developmental biology0303 health sciencesCrystallographyflavoproteinsFADResolution (electron density)TemperaturebanaanikärpänenDNAkidetiede(6-4) photolyase021001 nanoscience & nanotechnologyResearch PapersRADICAL TRANSFER(6–4) photolyaseroom-temperature structureCrystallographyphotolyasesDrosophila melanogasterRECONSTITUTIONX-ray crystallography1182 Biochemistry cell and molecular biologylämpötilaproteiinit0210 nano-technologyDeoxyribodipyrimidine Photo-LyasePHOTOACTIVATIONVisible spectrum

description

A crystal structure of a photolyase at room temperature confirms the structural information obtained from cryogenic crystallography and paves the way for time-resolved studies of the photolyase at an X-ray free-electron laser.

https://doi.org/10.1107/s2059798321005830