6533b858fe1ef96bd12b62ef
RESEARCH PRODUCT
Imaging of laser-excited tissue autofluorescence bleaching rates.
Alexey LihachevRenars ErtsJānis Spigulissubject
Materials scienceMaterials Science (miscellaneous)Multispectral imageImage processingSkin DiseasesIndustrial and Manufacturing EngineeringFluorescence spectroscopyFluorescencelaw.inventionPlanarOpticslawDigital image processingImage Processing Computer-AssistedHumansBusiness and International ManagementSkinPhotobleachingPixelbusiness.industryLasersHyperspectral imagingLaserMicroscopy FluorescenceFeasibility Studiesbusinessdescription
Experimental methodology for imaging of laser-excited tissue autofluorescence bleaching rates has been developed and clinically tested. The fluorescence images were periodically captured from the same tissue area over a certain time, with subsequent detection of the fluorescence intensity decrease rate at each image pixel and further imaging the planar distribution of those values. Spectral features at each image pixel were analyzed with a hyperspectral imaging camera. Details of the equipment and image processing are described as well as some measurement results that confirm the feasibility of the proposed technology.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2009-02-27 | Applied optics |