Histaminanaloge, 28. Mitt. 2-Aryloxyalkyl- und 2-Aminoalkylhistamine

6533b858fe1ef96bd12b6c79

RESEARCH PRODUCT

Histaminanaloge, 28. Mitt. 2-Aryloxyalkyl- und 2-Aminoalkylhistamine

subject

Amidine chemistry.chemical_compound Chemistry Stereochemistry Drug Discovery Pharmaceutical Science Imidazole Biological activity Ether Histamine H1 receptor Histamine H1 Antagonists Histamine

description

Als Histaminderivate mit H1-affinitatsvermittelnden Strukturelementen in 2-Stellung des Imidazolrings wurden 2-Aryloxyalkyl- und 2-Aminoalkylhistamine sowie das racemische 2-(1-Phenylethyl)histamin dargestellt und auf Histamin-H1-agonistische Aktivitat untersucht. Histamine Analogues, XXVIII: 2-(Aryloxyalkyl)- and 2-(Aminoalkyl)histamines As histamine derivatives with structures at position 2 of the imidazole ring, which mediate H1-receptor affinity, 2-(aryloxyalkyl)- and 2-(aminoalkyl)histamines as well as racemic 2-(1-phenylethyl)histamine were prepared and tested for histamine H1-agonistic activity.

year	journal	country	edition	language
1987-01-01	Archiv der Pharmazie

https://doi.org/10.1002/ardp.19873200208

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