Comparative Surface Morphology, Chemical Composition, and Cytocompatibility of Bio-C Repair, Biodentine, and ProRoot MTA on hDPCs

6533b859fe1ef96bd12b6f80

RESEARCH PRODUCT

Comparative Surface Morphology, Chemical Composition, and Cytocompatibility of Bio-C Repair, Biodentine, and ProRoot MTA on hDPCs

Francisco Javier Rodríguez-lozano Leopoldo Forner James Ghilotti María Pilar Pecci-lloret Julia Guerrero-gironés Sergio López-garcía Gianrico Spagnuolo Gianrico Spagnuolo Adrián Lozano Mari Carmen Llena José Luis Sanz

subject

cytocompatibility Biocompatibility vital pulp materials chemistry.chemical_element 02 engineering and technology Calcium Cell morphology lcsh:Technology Article Flow cytometry 03 medical and health sciences 0302 clinical medicine stomatognathic system dental pulp cells medicine General Materials Science MTT assay Viability assay calcium silicate materials Cytotoxicity lcsh:Microscopy lcsh:QC120-168.85 calcium silicate material medicine.diagnostic_test lcsh:QH201-278.5 Chemistry lcsh:T dental pulp cell 030206 dentistry 021001 nanoscience & nanotechnology stomatognathic diseases endodontic lcsh:TA1-2040 Pulp (tooth)lcsh:Descriptive and experimental mechanics lcsh:Electrical engineering. Electronics. Nuclear engineering 0210 nano-technology lcsh:Engineering (General). Civil engineering (General)lcsh:TK1-9971 Nuclear chemistry

description

Biocompatibility is an essential property for any vital pulp material that may interact with the dental pulp tissues. Accordingly, this study aimed to compare the chemical composition and ultrastructural morphology of Biodentine (Septodont, Saint Maur-des-Fosses, France), ProRoot MTA (Dentsply Tulsa Dental Specialties, Johnson City, TN, USA), and Bio-C Repair (Angelus, Londrina, PR, Brazil), as well as their biological effects on human dental pulp cells. Chemical element characterization of the materials was undertaken using scanning electron microscopy and energy dispersive X-ray analysis (SEM-EDX). The cytotoxicity was assessed by analyzing the cell viability (MTT assay), cell morphology (immunofluorescence assay), and cell attachment (flow cytometry assay). The results were statistically analyzed using ANOVA and Tukey&rsquo

year	journal	country	edition	language
2020-05-01	Materials

10.3390/ma13092189 https://www.mdpi.com/1996-1944/13/9/2189

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