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RESEARCH PRODUCT
A Guide to Designing a Memory fMRI Paradigm for Pre-surgical Evaluation in Temporal Lobe Epilepsy
Sarah BuckSarah BuckMeneka K. SidhuMeneka K. Sidhusubject
TLEgenetic structuresguiderecallbehavioral disciplines and activities050105 experimental psychologylcsh:RC346-429Temporal lobememory03 medical and health sciencesEpilepsy0302 clinical medicinemedicineMemory functions0501 psychology and cognitive scienceslcsh:Neurology. Diseases of the nervous systemModality (human–computer interaction)medicine.diagnostic_testRecall05 social sciencesfMRICognitionparadigmmedicine.diseasenervous systemNeurologyPerspectivemethodNeurology (clinical)Verbal memoryrecognitionPsychologyFunctional magnetic resonance imaging030217 neurology & neurosurgerypsychological phenomena and processesCognitive psychologydescription
There has been increasing interest in the clinical and experimental use of memory functional Magnetic Resonance Imaging (fMRI). The 2017 American Academy of Neurology practice guidelines on the use of pre-surgical cognitive fMRI suggests that verbal memory fMRI could be used to lateralize memory functions in people with Temporal Lobe Epilepsy (TLE) and should be used to predict post-operative verbal memory outcome. There are however technical and methodological considerations, to optimize both the sensitivity and specificity of this imaging modality. Below we discuss these constraints and suggest recommendations to consider when designing a memory fMRI paradigm.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2020-01-09 | Frontiers in Neurology |