6533b85bfe1ef96bd12bbe3d
RESEARCH PRODUCT
Recognition and characterization of small colonic neoplasia with high-definition colonoscopy using i-Scan is as precise as chromoendoscopy
Achim TreschMartin GoetzPeter R. GalleMarkus F. NeurathJonas MudterArthur HoffmanC. KagelRalf KiesslichStefan Biesterfeldsubject
medicine.medical_specialtyeducation.field_of_studyHepatologymedicine.diagnostic_testColorectal cancerSurrogate endpointbusiness.industryHigh definition endoscopyPopulationGastroenterologyColonoscopymedicine.diseaseTime efficientChromoendoscopymedicineHigh definitionRadiologyeducationbusinessdescription
Abstract Background The EPKi system (Pentax, Japan) enables resolution above HDTV. Aim of the study was to test the efficacy of HD+ alone and with the new post-processing digital filter i-Scan or chromoendoscopy (Methylene blue 0.1%) in screening for colorectal cancer. We focused on lesions less than 5 mm as a surrogate marker for the optical possibilities of the EPKi system. Methods The last 30 cm of the colon in a screening population were inspected with HD+ alone, in combination with i-Scan (2:1 randomisation) and subsequently with chromoendoscopy. All lesions were characterized and targeted biopsies were performed. Results i-Scan augmented in 69 patients the identification of lesions from 176 to 335 (p Conclusions HD+ colonoscopy with and without i-Scan unmask a plethora of small lesions but chromoendoscopy can even advance the number. However, i-Scan was able to predict neoplasia as precisely as chromoendoscopy and might shortly replace chromoendoscopy as a more time efficient tool.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2010-01-01 | Digestive and Liver Disease |