6533b85dfe1ef96bd12bdd6c
RESEARCH PRODUCT
Quality analysis of population-based information on cancer stage at diagnosis across Europe, with presentation of stage-specific cancer survival estimates: A EUROCARE-5 study.
Pamela MinicozziKaire InnosMaria-josé SánchezAnnalisa TramaPaul M. WalshRafael Marcos-grageraNadya DimitrovaLaura BottaOtto VisserSilvia RossiAndrea TavillaMilena SantM. HacklN. ZielonkeE. Van EyckenK. HenauZ. ValerianovaN. DimitrovaM. SekerijaL. DušekM. ZvolskýM. MägiT. AareleidN. MalilaK. SeppäA.m. BouvierJ. FaivreN. BossardZ. UhryM. ColonnaR. StabenowS. LuttmannA. EberleH. BrennerA. NenneckeJ. EngelG. Schubert-fritschleJ. HeidrichB. HolleczekA. KatalinicK. Clough-gorrG. MazzoleniA. BulatkoC. BuzzoniA. GiacominS. FerrettiA. BarchielliA. CaldarellaG. GattaM. SantH. AmashC. AmatiP. BailiF. BerrinoS. BonfarnuzzoL. BottaR. CapocacciaF. Di SalvoR. FoschiC. MarguttiE. MeneghiniP. MinicozziA. TramaD. SerrainoL. Dal MasoR. De AngelisM. CaldoraE. CarraniS. FrancisciA. KnijnS. MalloneD. PierannunzioP. RoazziS. RossiM. SantaquilaniA. TavillaF. PannozzoM. NataliR.a. FilibertiE. MaraniM. AutelitanoG. SpagnoliC. CirilliM. FuscoM.f. VitaleA. TrainaR. StaitiF. VitaleR. CusimanoM. MichiaraR. TuminoF. FalciniA.l. CaiazzoS. MasperoA.c. FanettiR. ZanettiS. RossoM. RuggeS. TognazzoS. PildavaG. SmailyteT.b. JohannesenJ. RachtanS. GóźdźR. MężykJ. BłaszczykK. KępskaM. Bielska-lasotaG. Forjaz De LacerdaM.j. BentoL. AntunesA. MirandaA. Mayer-da-silvaC. Safaei DibaM. Primic-zakeljE. AlmarA. MateosA. Lopez De MunainN. LarrañagaA. Torrella-ramosJ.m. Díaz GarcíaR. Jimenez-chillaronR. Marcos-grageraL. VilardellC. Moreno-iribasE. ArdanazM. LambeM. MousaviC. BouchardyM. UselS.m. EssH. FrickM. LorezS.m. EssC. HerrmannA. BordoniA. SpitaleI. KonzelmannO. VisserR. DamhuisR. OtterM. ColemanC. AllemaniB. RachetJ. RashbassJ. BroggioJ. VerneA. GavinD. FitzpatrickD.w. HuwsC. Whitesubject
Malemedicine.medical_specialtyCancer ResearchStage at diagnosiSurvivalConcordanceCancer registrieCancer registries ; Data quality ; Stage at diagnosis ; SurvivalSocio-culturaleReproducibility of ResultPredictive Value of TestCancer registries; Data quality; Stage at diagnosis; Survival; Data Accuracy; Europe; Female; Humans; Male; Neoplasm Metastasis; Neoplasms; Predictive Value of Tests; Reproducibility of Results; Survival Analysis; Neoplasm Staging; Registries; Oncology; Cancer Research03 medical and health sciences0302 clinical medicineBreast cancerPredictive Value of TestsNeoplasmsmedicineotorhinolaryngologic diseasesCancer registriesHumans030212 general & internal medicineRegistriesStage (cooking)Neoplasm MetastasisIntensive care medicineSurvival analysisCancer stagingNeoplasm Stagingbusiness.industryData qualityReproducibility of ResultsStage at diagnosismedicine.diseaseSurvival AnalysisCancer registryData AccuracyClinical trialNeoplasm MetastasiEuropeOncology030220 oncology & carcinogenesisData qualityNeoplasmFemaleSurvival AnalysibusinessHumandescription
Abstract Background Cancer registries (CRs) are fundamental for estimating cancer burden, evaluating screening and monitoring health service performance. Stage at diagnosis—an essential information item collected by CRs—has been made available, for the first time, by CRs participating in EUROCARE-5. We analysed the quality of this information and estimated stage-specific survival across Europe for CRs with good data quality. Data and methods Sixty-two CRs sent stage (as TNM, condensed TNM or extent of disease) for 15 cancers diagnosed in 2000–2007. We assessed the quality, partly by comparing stage according to the three systems. We also developed procedures to reconstruct stage (categories: local, regional, metastatic and unknown) using information from all three systems, thus minimising the amount of missing information. Results Moderate-to-excellent stage concordance was found for practically all 24 CRs, for which it was possible to compare at least two staging systems. However, since stage was often incorrectly assigned, and information on the presence/absence of metastases was often lacking, data on only 7/15 cancers from 34/62 CRs (15 countries) were of sufficient quality for further analysis. Cases diagnosed ≥70 years had more advanced (or lacking) stage– and worse stage-specific survival than those Conclusions Many European CRs collect and record reasonably accurate stage information. Others have difficulties. Both the completeness of primary data and the accuracy of stage coding need to be improved in order for CRs to fulfil their expanding roles in cancer control. We propose our stage reconstruction/checking procedures as a means of fully exploiting the stage information provided by EUROCARE CRs. More advanced (or lacking) stage at diagnosis plus poorer stage-specific survival in the elderly are worrying.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2017-01-01 | European journal of cancer (Oxford, England : 1990) |