Characterization of a Catalase-Negative Methicillin-Resistant Staphylococcus aureus Strain

6533b85dfe1ef96bd12bdd74

RESEARCH PRODUCT

Characterization of a Catalase-Negative Methicillin-Resistant Staphylococcus aureus Strain

Sucharit Bhakdi B. M. Grüner H.-g. Meyer U. Wulf Ekkehard Siegel Shan-rui Han

subject

DNA Bacterial Male Microbiology (medical)Staphylococcus aureus Sequence analysis Molecular Sequence Data Biology medicine.disease_cause Staphylococcal infections Microbiology parasitic diseases medicine Humans Gene Aged chemistry.chemical_classification Strain (chemistry)Bacteriology Sequence Analysis DNA Staphylococcal Infections Catalase bacterial infections and mycoses medicine.disease Methicillin-resistant Staphylococcus aureus Enzyme chemistry Staphylococcus aureus Catalase biology.protein Methicillin Resistance

description

ABSTRACT We describe an unusual clinical strain of catalase-negative methicillin-resistant Staphylococcus aureus sensu stricto. Sequence analysis of its catalase gene showed 99.60% identities to the catalase genes of the reference strains. A 5-base deletion, however, led to a shift of the nucleotide reading frame and a loss of the enzymatic activity.

year	journal	country	edition	language
2007-08-01	Journal of Clinical Microbiology

https://doi.org/10.1128/jcm.02457-06

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