6533b85efe1ef96bd12bfb84

RESEARCH PRODUCT

Early stage screening of breast cancer using electrochemical biomarker detection

Mohammad HasanzadehNasrin ShadjouMiguel De La Guardia

subject

Oncologymedicine.medical_specialtybusiness.industry010401 analytical chemistryNew materialsNanotechnology02 engineering and technology021001 nanoscience & nanotechnologymedicine.diseaseKey issues01 natural sciences0104 chemical sciencesAnalytical ChemistryTumor BiomarkersBreast cancerInternal medicineMedicineBiomarker (medicine)Electrochemical biosensorStage (cooking)0210 nano-technologybusinessSpectroscopyBiomedicine

description

Recently researchers have driven their attention in the development of biosensors for breast cancer detection using different biomarkers. This review reports a systematic study of the usefulness of marker-based electrochemical biosensors in breast cancer and its early diagnosis. Also, various types of electro-analytical methods for early stage screening of breast cancer were discussed. The emphasis is placed on immune-, geno- cyto- and enzyme-biosensing strategies. In addition, the advantages offered by some nano-materials in detection of breast cancer biomarkers are illustrated with representative recent examples that highlight the scientific interest in widening the use of new materials/methods in electrochemical biosensing methods. We also present a comprehensive overview of current developments and key issues in the determination of some breast cancer biomarkers, with an emphasis on evaluating the methods.

https://doi.org/10.1016/j.trac.2017.04.006