Hemmung von DNA-Synthese und Zellvermehrung durch Apurins�ure und Apyrimidins�ure

6533b85efe1ef96bd12bfd13

RESEARCH PRODUCT

Hemmung von DNA-Synthese und Zellvermehrung durch Apurins�ure und Apyrimidins�ure

subject

Pharmacology chemistry.chemical_classification Purine Pyrimidine education General Medicine Biology Molecular biology In vitro Tissue culture chemistry.chemical_compound Enzyme Biochemistry chemistry In vivo mental disorders Apurinic Acid psychological phenomena and processes DNA

description

Apurinic acid (APA) and apyrimidinic acid (APyA) prepared from deoxyribonucleic acid (DNA) by removing either purine or pyrimidine bases have been reported to inhibit enzymatic DNA-synthesis in vitro (Heicke, 1970). The present paper deals with in vivo effects of APA and APyA on mammalian cells in tissue culture.

year	journal	country	edition	language
1968-01-01	Naunyn-Schmiedebergs Archiv f�r Pharmakologie und Experimentelle Pathologie

https://doi.org/10.1007/bf00537945

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