6533b860fe1ef96bd12c3a87

RESEARCH PRODUCT

Autofluorescence imaging of basal cell carcinoma by smartphone RGB camera

Inesa FerulovaAlexey LihachevMarta LangeIlze LihacovaJānis SpigulisAlexander Derjabo

subject

PorphyrinsSkin NeoplasmsLightComputer scienceBiomedical EngineeringDermoscopyImage processingFluorescenceBiomaterialsOpticsmedicineHumansBasal cell carcinomaNevusSkinPhotobleachingPixelbusiness.industrySkin autofluorescenceNADmedicine.diseaseAtypical nevusAtomic and Molecular Physics and OpticsElectronic Optical and Magnetic MaterialsAutofluorescenceFluorescence intensityMicroscopy FluorescenceCarcinoma Basal CellRGB color modelCollagenSmartphonebusinessBiomedical engineering

description

The feasibility of smartphones for in vivo skin autofluorescence imaging has been investigated. Filtered autofluorescence images from the same tissue area were periodically captured by a smartphone RGB camera with subsequent detection of fluorescence intensity decreasing at each image pixel for further imaging the planar distribution of those values. The proposed methodology was tested clinically with 13 basal cell carcinoma and 1 atypical nevus. Several clinical cases and potential future applications of the smartphone-based technique are discussed.

https://doi.org/10.1117/1.jbo.20.12.120502