6533b861fe1ef96bd12c43a9
RESEARCH PRODUCT
Efficient Self-Assembly of Di-, Tri-, Tetra-, and Hexavalent Hosts with Predefined Geometries for the Investigation of Multivalency
Igor LinderStefan LeiseringRakesh PuttreddyChristoph A. SchalleyNadine RadesKari Rissanensubject
chemistry.chemical_classificationStereochemistrycrown ethersOrganic ChemistrySupramolecular chemistrychemistry.chemical_elementIsothermal titration calorimetryGeneral ChemistrymultivalencyCombinatorial chemistrysupramolecular chemistryCatalysisRutheniumCoordination complexBipyridinechemistry.chemical_compoundstomatognathic systemchemistrycoordination chemistryMoleculeSelf-assemblyTerpyridineta116pseudorotaxanesdescription
Coordination-driven self-assembly of differently shaped di- to hexavalent crown-ether host molecules is described. A series of [21]crown-7- and [24]crown-8-substituted bipyridine and terpyridine ligands was synthetized in a "toolbox" approach. Subsequent coordination to 3d transition metal and ruthenium(II) ions provides an easy and fast access to host assemblies with variable valency and pre-defined orientations of the crown-ether moieties. Preliminary isothermal calorimetry (ITC) titrations provided promising results, which indicated the host complexes under study to be suitable for the future investigation of multivalent and cooperative binding. The hosts described herein will also be suitable for the construction of various multiply threaded mechanically interlocked molecules.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2015-07-21 | Chemistry - A European Journal |