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RESEARCH PRODUCT
Maternal coffee drinking in pregnancy and risk of small for gestational age birth
Francesca ChiaffarinoFabio ParazziniFabio ParazziniSonia CiprianiLiliane ChatenoudVito ChianteraLuca TozziLuigi Fedelesubject
Adultmedicine.medical_specialtyAdolescentEpidemiologyPregnancy Trimester ThirdMedicine (miscellaneous)CoffeeRisk FactorsPregnancyEpidemiologyOdds RatioHumansMedicineRisk factorPregnancyNutrition and DieteticsDose-Response Relationship Drugbusiness.industryObstetricsRisk FactorConfoundingInfant NewbornPregnancy Outcomemedicine.diseaseConfidence intervalDietSmall for gestational age birthPregnancy Trimester FirstCase-Control StudiesPregnancy Trimester SecondInfant Small for Gestational AgeGestationSmall for gestational ageTerm BirthDiet; Epidemiology; Small for gestational age birthFemaleCase-Control StudiebusinessHumanFood Sciencedescription
Objective: We have analysed the association between coffee drinking before and during the three trimesters of pregnancy and risk of small for gestational age (SGA) birth. Methods: Cases were 555 women who delivered SGA births (ie <10th percentile according Italian standard). The controls included 1966 women who gave birth at term (≥37 weeks of gestation) to healthy infants of normal weight. Results: In comparison with nondrinkers, the ORs for SGA birth were 1.3 (95% confidence interval, CI, 0.9–1.9) for consumption of four or more cups of coffee/day before pregnancy, and 1.2 (95% CI 0.8–1.8), 1.2 (95% CI 0.8–1.8) and 0.9 (95% CI 0.6–1.4) for consumption of three or more cups of coffee/day during the first, second and third trimester of pregnancy, respectively. Conclusion: These findings were consistent in women who delivered preterm and at term births and were not affected by potential confounding such as smoking. Sponsorship: Partly supported by the Commission of the European Communities (Contract No. QLK1-CT-2000-00069).
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2005-01-01 |