6533b861fe1ef96bd12c59ab
RESEARCH PRODUCT
A survey of seroprevalence of human papillomavirus types 16, 18 and 33 among children.
Carina EklundJoakim DillnerLena DillnerVeronika Af GeijersstamJohn T. SchillerMartin SappZhaohui Wangsubject
Cancer Researchmedicine.medical_specialtyAdolescentvirusesAntibodies ViralSerologyCapsidInternal medicineEpidemiologymedicineSeroprevalenceHumansChildPapillomaviridaeSwedenbusiness.industryPublic healthPapillomavirus InfectionsHPV infectionInfant Newbornvirus diseasesInfantmedicine.diseasefemale genital diseases and pregnancy complicationsNatural historyTumor Virus InfectionsOncologyEl NiñoChild PreschoolImmunologyFemaleViral diseasebusinessdescription
The importance and natural history of HPV infections in childhood is incompletely understood. We performed a survey for presence of serum antibodies to HPV capsids among 1031 children aged 0 to 13 years, resident in Stockholm, Sweden. The HPV seroprevalence among these children was 3.0% for HPV16, 0.6% for HPV18 and 2.7% for HPV33. By comparison, among simultaneously analyzed positive control panels comprising women with CIN or healthy women with type-specific cervical HPV DNA, seroprevalence of HPV 16, 18 and 33 was 69%, 58% and 63% respectively. The results suggest that HPV infection in childhood is not common.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1999-02-09 | International journal of cancer |