6533b862fe1ef96bd12c60bd
RESEARCH PRODUCT
Kinetische Analyse der Calcium-Kompartimente im Meerschweinchenherzen unter Kontrollbedingungen und Strophanthineinwirkung
W. KlausW. KlausR. Krebssubject
Pharmacologymedicine.medical_specialtyChromatographyChemistryPharmacology toxicologyGeneral MedicineHeart musclesOuabainGuinea pigEndocrinologyInternal medicinemedicineQuantitative analysis (chemistry)Isovolumetric contractionmedicine.drugdescription
A quantitative analysis of myocardial Ca-metabolism was carried out on isolated, isovolumetric (10 ml/min) perfused guinea pig hearts by combined determinations of the total Ca-content and kinetics of 45Ca-efflux (collecting period 60 min) (Fig. 1). The kinetics of 45Ca-uptake was estimated by extrapolating 45Ca-efflux curves of heart muscles isotopically loaded for different times (2, 5, 10, 30 60 min) to the end of the loading-period (Fig. 2).
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1974-01-01 | Naunyn-Schmiedeberg's Archives of Pharmacology |