6533b86cfe1ef96bd12c89c4

RESEARCH PRODUCT

Associated arterial and venous cerebral manifestations in Behçet's disease

Yannick BéjotJean François BesancenotH DevilliersM. GiroudCéline BrenièreBenoit DelpontP. BielefeldMaxime SamsonChristelle Blanc

subject

Cerebral veinsmedicine.medical_specialtymedicine.diagnostic_testbusiness.industryBehcet's disease030204 cardiovascular system & hematologymedicine.diseaseeye diseasesstomatognathic diseases03 medical and health sciencesVenous thrombosis0302 clinical medicineIntracranial ThrombosisNeurologyInternal medicineEtiologymedicineCardiologyNeurology (clinical)Vasculitisbusiness030217 neurology & neurosurgeryFibrinolytic agentCerebral angiography

description

Behcet's disease is a rare multisystemic vasculitis with an etiology that is still unknown. Neurological manifestations may be seen in approximately 5-15% of patients, and both parenchymal and extraparenchymal neurological involvement has been described. When cerebral venous thrombosis (CVT) is the main extraparenchymal manifestation of Behcet's disease, the condition is then dubbed "angio-Behcet's syndrome". However, arterial involvement is extremely rare, with only one reported case of vasculo-neuro-Behcet's disease, characterized by both venous and intracranial arterial involvement - until now. This report is of two patients diagnosed with Behcet's disease characterized by the concomitant presence of both cerebral arterial manifestations and CVT.

https://doi.org/10.1016/j.neurol.2017.06.031