6533b86efe1ef96bd12cb216

RESEARCH PRODUCT

Peptide based biosensors

Mohammad HasanzadehAyub KarimzadehMiguel De La GuardiaNasrin Shadjou

subject

Materials scienceSensing applications010401 analytical chemistryMicrofluidicsNanotechnology02 engineering and technology021001 nanoscience & nanotechnology01 natural sciences0104 chemical sciencesAnalytical ChemistryTumor BiomarkersElectrochemiluminescenceMultiplex0210 nano-technologyBiosensorSpectroscopy

description

Abstract This review provides an overview of the various types of (bio)sensors based on peptides for their analytical use, along with significant advances over the last several years in related technologies. So, it will be described: i) principles in biosensing using peptides ii) aspects of fabrication in the perspective of (bio)sensing applications iii) potential of electrochemical, electrochemiluminescence, photoelectrochemical, and optical (bio)sensors for the determination of target analytes within sub-nanomolar range also discussing the main problems in (bio)sensing iv) multiplex electrochemical and optical (bio)sensors, both with and without labels. v) Latest developments in the applications of (bio)sensors methods for detection of important analytes in real samples. vi) the application of nanotechnology and microfluidic technology on peptide based biosensing.

https://doi.org/10.1016/j.trac.2018.07.018