6533b86efe1ef96bd12cb260

RESEARCH PRODUCT

Stereoselective glycosylation of Alcohols and Silyl Ethers Using Glycosyl Fluorides and Boron Trifluoride Etherate

Wilfried SagerHorst Kunz

subject

inorganic chemicalschemistry.chemical_classificationanimal structuresGlycosylationSilylationChemistryOrganic ChemistryAlcoholEthermacromolecular substancesFuranoseBiochemistryCatalysiscarbohydrates (lipids)Inorganic Chemistrychemistry.chemical_compoundPyranoseDrug DiscoveryOrganic chemistrylipids (amino acids peptides and proteins)GlycosylPhysical and Theoretical ChemistryBoron trifluoride

description

The stereoselective glycosylation of alcohols and their silyl ethers has been achieved using O-alkyl-, O-acyl-, and acetal-protected glycosyl fluorides of the pyranose and furanose series and boron trifluoride etherate in CH2Cl2.

https://doi.org/10.1002/hlca.19850680134