Chronic hydrogen peroxide intake and peroxide metabolizing enzyme activities in some tissues of mice and rats

6533b870fe1ef96bd12cfb6c

RESEARCH PRODUCT

Chronic hydrogen peroxide intake and peroxide metabolizing enzyme activities in some tissues of mice and rats

M. Kihlström Veikko Vihko A. Salminen

subject

Male Lipid Peroxides medicine.medical_specialty Antioxidant medicine.medical_treatment Kidney Mice Selenium Cellular and Molecular Neuroscience chemistry.chemical_compound Oral administration Internal medicine medicine Animals Hydrogen peroxide Molecular Biology Pharmacology chemistry.chemical_classification Glutathione Peroxidase Kidney Water Deprivation biology Muscles Myocardium Glutathione peroxidase Skeletal muscle Hydrogen Peroxide Cell Biology Catalase Endocrinology medicine.anatomical_structure Liver chemistry Catalase Toxicity biology.protein Molecular Medicine

description

Chronic daily intake of 0.5% H2O2 in drinking water decreased Se-dependent glutathione peroxidase (Se-GSHPx) activity in rat skeletal muscle, kidney and liver. Non-Se GSHPx activity decreased in kidney. Deprivation of drinking water decreased Se-GSHPx activity in kidney and non-Se GSHPx activity in kidney and liver. H2O2 intake decreased activity of catalase in rat skeletal muscle. H2O2 intake or water deprivation caused no changes in these enzyme activities in mice.

year	journal	country	edition	language
1986-09-15	Experientia

https://doi.org/10.1007/bf01940713

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