6533b871fe1ef96bd12d2624

RESEARCH PRODUCT

Infection of the upper extremity by Mycobacterium marinum in a 3-year-old boy--diagnosis by 16S-rDNA analysis.

S. BhakdiM. HusmannDaniel JonasJ. KunkelV. EngelA. Feddersen

subject

Microbiology (medical)DNA BacterialMalePathologymedicine.medical_specialtyDNA RibosomalMycobacteriumAgar plateClarithromycinRNA Ribosomal 16SmedicineHumansMycobacterium marinumMycobacterium Infectionsbiologybusiness.industryNodule (medicine)General Medicinebiology.organism_classificationInfectious DiseasesChild PreschoolArmmedicine.symptombusinessCefuroximeRifampicin16s rdna analysismedicine.drugMycobacterium

description

A 3-year-old boy developed several subcutaneous nodular lesions on his right arm. Based on the histological examination of one of these nodules furunculosis was suspected and cefuroxime was tentatively given. However, acid-fast bacilli were then detected in the tissue specimen and a few colonies of acid fast, gram-positive rods grew on blood agar. Definitive species diagnosis (Mycobacterium marinum) was rapidly achieved by automated sequencing of amplified 16S-rDNA and antimicrobial therapy was adjusted according to the available literature. After 3 weeks of treatment with clarithromycin, rifampicin and protionamid regression of the nodular lesions was evident.

yearjournalcountryeditionlanguage
1996-01-01Infection
10.1007/bf01780651https://pubmed.ncbi.nlm.nih.gov/8852464