6533b872fe1ef96bd12d2e8e
RESEARCH PRODUCT
Nanovector formation by functionalization of TRAIL ligand on single-walled carbon nanotube: Experimental and theoretical evidences
Fabien PicaudEric DelabrousseXavier DevauxMicheau OlivierEric DuvergerAl Batoul ZakariaGuillaume HerlemTijani Gharbisubject
[SPI.ACOU]Engineering Sciences [physics]/Acoustics [physics.class-ph]Materials scienceLigandEnergy-dispersive X-ray spectroscopyStacking[ PHYS.COND.CM-MS ] Physics [physics]/Condensed Matter [cond-mat]/Materials Science [cond-mat.mtrl-sci]General Physics and AstronomyNanotechnologyCarbon nanotubePhotochemistrylaw.invention[SPI.MAT]Engineering Sciences [physics]/MaterialsX-ray photoelectron spectroscopylawScanning transmission electron microscopy[PHYS.COND.CM-MS]Physics [physics]/Condensed Matter [cond-mat]/Materials Science [cond-mat.mtrl-sci]Surface modificationPhysical and Theoretical Chemistry[SPI.NANO]Engineering Sciences [physics]/Micro and nanotechnologies/MicroelectronicsSpectroscopydescription
Équipe 104 : Nanomatériaux; International audience; The synthesis and the characterization of a novel nanovector based on oxidized single-walled carbon nanotubes (SWCNT) functionalized with tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) via noncovalent 1-pyrenebutanoic acid N-hydrosuccinimid ester (PSE) is described. Experimental noncovalent functionalized SWCNT by PSE are compared to full DFT theoretical predictions. For this, several experimental techniques are gathered to prove the well functionalization of oxidized SWCNT by pi-pi stacking such as micro Raman and XPS spectroscopy analysis coupled to full-DFT calculations. Scanning transmission electron microscopy (STEM) coupled to energy dispersive spectroscopy (EDS) underline the presence of TRAIL ligands on the nanovector.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2015-07-01 |