6533b872fe1ef96bd12d3a91
RESEARCH PRODUCT
Vitamin D in pediatric age: consensus of the Italian Pediatric Society and the Italian Society of Preventive and Social Pediatrics, jointly with the Italian Federation of Pediatricians.
Irene CetinGiuseppe Di MauroFrancesco VierucciRino AgostinianiDaniele Giovanni GhiglioniFabio CardinaleDomenico CaredduFlavia ProdamDiego PeroniLuigi TerraccianoGiuseppe SaggeseElena ChiappiniGiovanni CorselloMichele Miraglia Del GiudiceMaddalena MassariGian Luigi De' AngelisEmanuele Miraglia Del GiudiceGianni Bonasubject
Pediatricsmedicine.medical_specialtyConsensusAdolescentSupplementationConsensu030209 endocrinology & metabolismReviewAdolescentsVitaminvitamin D deficiencylaw.inventionNutritional Rickets03 medical and health sciences0302 clinical medicineRandomized controlled triallaw030225 pediatricsVitamin D and neurologymedicineMusculoskeletal healthHumansVitamin DChildPathologicalChildrenSocieties MedicalDietary Supplementvitamin D childrenVitamin d supplementationbusiness.industrylcsh:RJ1-570Infant NewbornInfantHypovitaminosis Dlcsh:PediatricsPediatric ageGeneral MedicineVitaminsmedicine.diseaseVitamin D DeficiencyItalyChild PreschoolPediatrics Perinatology and Child HealthDietary SupplementsDeficiencybusinessHumandescription
Abstract Vitamin D plays a pivotal role in the regulation of calcium-phosphorus metabolism, particularly during pediatric age when nutritional rickets and impaired bone mass acquisition may occur. Besides its historical skeletal functions, in the last years it has been demonstrated that vitamin D directly or indirectly regulates up to 1250 genes, playing so-called extraskeletal actions. Indeed, recent data suggest a possible role of vitamin D in the pathogenesis of several pathological conditions, including infectious, allergic and autoimmune diseases. Thus, vitamin D deficiency may affect not only musculoskeletal health but also a potentially wide range of acute and chronic conditions. At present, the prevalence of vitamin D deficiency is high in Italian children and adolescents, and national recommendations on vitamin D supplementation during pediatric age are lacking. An expert panel of the Italian Society of Preventive and Social Pediatrics reviewed available literature focusing on randomized controlled trials of vitamin D supplementation to provide a practical approach to vitamin D supplementation for infants, children and adolescents.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2018-01-01 | Italian journal of pediatrics |