6533b873fe1ef96bd12d59c2

RESEARCH PRODUCT

Separation of Nanoparticles by Gel Electrophoresis According to Size and Shape

Matthias HanauerInga ZinsAnd Alexander LotzCarsten SönnichsenSebastien Pierrat

subject

SilverMaterials scienceAnalytical chemistryNanoparticleBioengineeringengineering.materialSilver nanoparticleNanotechnologyComputer SimulationGeneral Materials ScienceParticle SizeSurface plasmon resonancechemistry.chemical_classificationGel electrophoresisMechanical EngineeringGeneral ChemistryPolymerCondensed Matter PhysicsNanostructuresModels ChemicalchemistryAgarose gel electrophoresisengineeringNoble metalComet AssayGoldParticle size

description

We demonstrate the separation of gold and silver nanoparticles according to their size and shape by agarose gel electrophoresis after coating them with a charged polymer layer. The separation is monitored optically using the size- and shape-dependent plasmon resonance of noble metal particles and confirmed by transmission electron microscopy (TEM). Electrophoretic mobilities are quantitatively explained by a model based on the Henry formula, providing a theoretical framework for predicting gel mobilities of polymer coated nanoparticles.

https://doi.org/10.1021/nl071615y