6533b874fe1ef96bd12d6445

RESEARCH PRODUCT

Communication and ethical considerations for fertility preservation for patients with childhood, adolescent, and young adult cancer

Riccardo HauptClarisa R. GraciaGabriele CalaminusJacqueline J. LoonenIsabelle DemeestereKirsi JahnukainenLeontien C. M. KremerBarbara A. LockartHanneke M Van SantenKaren BurnsKaren BurnsWim J. E. TissingRichard N. YuEva Maria TinnerLouis S. ConstineThorsten LangerOgechukwu A AsogwaW. Hamish B. WallaceSebastian J C M M NeggersErik A. H. LoeffenMarianne D. Van De WeteringSarah E HunterMargreet A. VeeningLisa B. KenneyJulianne ByrneClaire BergerJoanne Frankel KelvinNatascia Di IorgiRoderick SkinnerRoderick SkinnerAns M M Van PeltDaniel M. GreenRichard A AndersonHolly R. HoefgenMarij Dinkelman-smitHerman TournayeEveline Stutz-grunderMarleen Van De BergAndreas RanftChris M VerhaakChristian DenzerAndrica De VriesKenny A. Rodriguez-wallbergKenny A. Rodriguez-wallbergMichelle PeateLillian R. MeachamJoop S.e. LavenRenée L. MulderRejin KebudiCornelis B. LambalkAnna Font-gonzalezNorbert W PaulJennifer LevineRod T. MitchellCatharyn SternEline Van Dulmen-den BroederTamara DieschJames L. KloskyAntoinette AnazodoAntoinette AnazodoArmando LorenzoAnnelies M E BosDesiree GrabowWendy Van DorpAndreas MeissnerUta DirksenGwendolyn P. QuinnMelissa M. HudsonBob PhillipsDamon R. ReedAleksander GiwercmanJulia InthornMarry M. Van Den Heuvel-eibrinkJ. D. BeckLeena NahataAlexandra BrownsdonPeter KaatschAnke BarnbrockJill P. Ginsberg

subject

InfertilityAdultMalemedicine.medical_specialtyAdolescentfertility preservationmedia_common.quotation_subjectMEDLINEMedizinFertilityGuidelines as Topic03 medical and health sciences0302 clinical medicineCancer SurvivorsSDG 3 - Good Health and Well-beingNeoplasmsMedicineHumansgonadotoxic therapiesFertility preservationYoung adultGrading (education)Childmedia_commonchildhoodCancer030219 obstetrics & reproductive medicinebusiness.industryCancerGuidelinemedicine.diseaseOncology030220 oncology & carcinogenesisFamily medicineDisease Progressionyoung adultFemalebusinessinfertilityreproductive medicine

description

Patients with childhood, adolescent, and young adult cancer who will be treated with gonadotoxic therapies are at increased risk for infertility. Many patients and their families desire biological children but effective communication about treatment-related infertility risk and procedures for fertility preservation does not always happen. The PanCareLIFE Consortium and the International Late Effects of Childhood Cancer Guideline Harmonization Group reviewed the literature and developed a clinical practice guideline that provides recommendations for ongoing communication methods for fertility preservation for patients who were diagnosed with childhood, adolescent, and young adult cancer at age 25 years or younger and their families. Moreover, the guideline panel formulated considerations of the ethical implications that are associated with these procedures. Grading of Recommendations Assessment, Development and Evaluation methodology was used to grade the evidence and recommendations. In this clinical practice guideline, existing evidence and international expertise are combined to develop transparent recommendations that are easy to use to facilitate ongoing communication between health-care providers and patients with childhood, adolescent, and young adult cancer who might be at high risk for fertility impairment and their families.

10.1016/s1470-2045(20)30595-7http://www.scopus.com/inward/record.url?scp=85100094498&partnerID=8YFLogxK