Inflammation et maladies métaboliques : analyse par imagerie du métabolisme des lipoprotéines et lipopolysaccharides au cours de l’inflammation

2021

LPS (lipopolysaccharides) are endotoxins originating from Gram-negative bacteria. They have been extensively described for their ability to interact with and disrupt the intestinal barrier. These toxins are able to cross the gut barrier and to pass into the blood (endotoxemia), leading tolow-grade metabolic inflammation or to a severe inflammatory syndrome (SIRS). Fortunately, some circulating proteins such as PLTP (Phospholipid Transfer Protein) are able to transfer LPS to plasma lipoproteins in order to inactivate and detoxify them.The main goals of this study were to investigate the metabolic fate of LPS from the gut and peritoneal cavity but also the influence of PLTP on these toxins in…

Pulp sensibility tests responses in patients with anxiety and depression

2021

In view of the importance of pulp sensibility tests in clinical decision-making and the impact of psychological factors on test results, we evaluated in this study dental pulp responses to pulp sensibility tests (ie, cold and electric) in patients with anxiety and depression.A number of 90 people age 20 to 30 participated in the study, including 30 healthy and 60 with anxiety and depression, whose disorder was approved by a psychiatrist based on the Symptom Checklist 90-R questionnaire. Pulp sensibility tests included electric and cold ones were performed on lateral mandibular teeth. The cold test results were recorded based on the visual analogue scale (VAS) pain scoring (0 no response, 10…

Intrinsic Point Defects in Silica for Fiber Optics Applications

2021

Due to its unique properties, amorphous silicon dioxide (a-SiO2) or silica is a key material in many technological fields, such as high-power laser systems, telecommunications, and fiber optics. In recent years, major efforts have been made in the development of highly transparent glasses, able to resist ionizing and non-ionizing radiation. However the widespread application of many silica-based technologies, particularly silica optical fibers, is still limited by the radiation-induced formation of point defects, which decrease their durability and transmission efficiency. Although this aspect has been widely investigated, the optical properties of certain defects and the correlation betwee…

Renato Guttuso and Sicily. For awidespread museum of the master of Bagheria

2021

Il contributo propone un approfondimento sulla figura di Renato Guttuso, artista siciliano che occupa un posto di rilievo nel panorama della pittura europea del XX secolo, attraverso ladisamina delle sue opere presenti in Sicilia,svolta alla luce dei più aggiornati studi sul legame dell’artista con la sua terra d’origine. Oltre al Museo Guttuso, fondato a Bagheria grazie a un lascito dell’artista, e al Complesso Monumentale dello Steridi Palermo, dove recentemente il suo capolavoro internazionalmente noto La Vucciriaè stato oggetto di un nuovo allestimento, si contano numerose sul territori siciliano le testimonianze della sua ricerca multiforme, grazie alla presenza di diverse realtà istit…

Lessons From COVID-19: Physical Exercise Can Improve and Optimize Health Status

2021

The outbreak of Coronavirus Disease 2019 (COVID-19) has caused increasing challenges for healthcare systems globally. The disease spread rapidly from Wuhan to the rest of the world, involving more than 400 million individuals and including more than 5 million deaths. In dealing with the pandemic, China and other countries took protective measures such as promoting social distancing, canceling public gatherings, closing schools, quarantining, and imposing lockdowns. All these measures lead to physical inactivity. Being physically inactive has significant repercussions on the status of physical and mental wellbeing, and it is associated with anxiety, stress, increased chronic disease risk, an…

Employment status and occupational positions of childhood cancer survivors from Denmark, Finland and Sweden: A Nordic register-based cohort study fro…

2021

Background: A childhood cancer diagnosis and late effects of treatment may affect survivors' possibilities of employment or highly skilled occupations later in life. In this study, we compared the employment and occupational status of childhood cancer survivors with population comparisons and siblings.Methods: In a cohort study based on Nordic registers, we identified 10 461 survivors of childhood cancer diagnosed before age 20 years in Denmark, Finland and Sweden since 1971. Survivors were compared with 48 928 population comparisons matched to survivors by age, sex and geographical region and 12 605 siblings of survivors. Annual outcome information on employment, unemployment, health-relat…

Uniformization of metric surfaces using isothermal coordinates

2021

We establish a uniformization result for metric surfaces - metric spaces that are topological surfaces with locally finite Hausdorff 2-measure. Using the geometric definition of quasiconformality, we show that a metric surface that can be covered by quasiconformal images of Euclidean domains is quasiconformally equivalent to a Riemannian surface. To prove this, we construct suitable isothermal coordinates.

Typification of 14 names in the Dianthus virgineus group (Caryophyllaceae)

2021

The nomenclature of 14 taxa from Central and Southern Europe within the Dianthus virgineus group is discussed. Dianthus aggericola Jord., D. collivagus Jord., D. consimilis Jord., D. orophilus Jord., D. saxicola Jord., D. juratensis Jord. are here lectotypified by specimens from the Jordan herbarium in LY, while D. godronianus Jord. by a specimen in P. Dianthus subacaulis Vill. is neotypified by a specimen collected on Mont Ventoux (S. France) and housed in MPU. For D. sylvestris Wulfen, a lectotype is here designated and its previous neotypification is discussed. Dianthus caryophyllus var. tenuifolius Moris, D. caryophyllus f. minor Moris and D. sylvestris var. garganicus Ten. are lectotyp…

Neuroendoscopic Navigated One-Step Removal of Crossed Ventricular Catheter Fragments: Technical Note

2021

Abstract Introduction Neuroendoscopy plays an important role in minimally invasive neurosurgery. The authors reported an interesting case of a pediatric patient with multiple ventriculoperitoneal shunt (VPS) revision surgeries, presenting with VPS infection and with two crossed intraventricular floating catheter fragments, successfully removed through a neuroendoscopic navigated one-step procedure. A literature review regarding this exceedingly rare condition has also been discussed. Case Description An 11-year-old female patient with a history of congenital hydrocephalus was admitted to the emergency department with symptoms of intracranial hypertension, psychomotor agitation, and tetrapar…

Pasquali, P. - Héritocratie. Les élites, les grandes écoles et les mésaventures du mérite

2021

« L’héritocratie n’est pas une méritocratie dégénérée, ou une technocratie aux bases élargies ; ce concept désigne l’ensemble des capacités d’agir, individuelles ou collectives, que les grandes écoles et, plus largement, les filières d’élite mettent en œuvre à chaque période pour conserver ou accroître leurs privilèges et leur légitimité face aux crises, critiques ou réformes susceptibles d’aller contre leurs intérêts. Plus précisément, il renvoie aux stratégies de résistance et de promotion ...

Robust Antigen-Specific T Cell Activation within Injectable 3D Synthetic Nanovaccine Depots

2021

Contains fulltext : 244693.pdf (Publisher’s version ) (Open Access) Synthetic cancer vaccines may boost anticancer immune responses by co-delivering tumor antigens and adjuvants to dendritic cells (DCs). The accessibility of cancer vaccines to DCs and thereby the delivery efficiency of antigenic material greatly depends on the vaccine platform that is used. Three-dimensional scaffolds have been developed to deliver antigens and adjuvants locally in an immunostimulatory environment to DCs to enable sustained availability. However, current systems have little control over the release profiles of the cargo that is incorporated and are often characterized by an initial high-burst release. Here,…

Dynamical learning of a photonics quantum-state engineering process

2021

Abstract. Experimental engineering of high-dimensional quantum states is a crucial task for several quantum information protocols. However, a high degree of precision in the characterization of the noisy experimental apparatus is required to apply existing quantum-state engineering protocols. This is often lacking in practical scenarios, affecting the quality of the engineered states. We implement, experimentally, an automated adaptive optimization protocol to engineer photonic orbital angular momentum (OAM) states. The protocol, given a target output state, performs an online estimation of the quality of the currently produced states, relying on output measurement statistics, and determine…

Positron Annihilation Lifetime Spectroscopy Insight on Free Volume Conversion of Nanostructured MgAl2O4 Ceramics

2021

H.K. and A.I.P. are grateful for the support from the COST Action CA17126. H.K. was also supported by the Ministry of Education and Science of Ukraine (project for young researchers No. 0119U100435). In addition, I.K. and H.K. were also supported by the National Research Foundation of Ukraine via project 2020.02/0217, while the research of A.I.P. was funded by the Latvian research council via the Latvian National Research Program under the topic ?High-Energy Physics and Accelerator Technologies?, Agreement No: VPP-IZM-CERN-2020/1-0002. In addition, the research of A.I.P. has been supported by the Latvian-Ukrainian Grant LV-UA/2021/5. The Institute of Solid State Physics, University of Latvi…

WhatsApp Messenger use in oncology: a narrative review on pros and contras of a flexible and practical, non-specific communication tool.

2021

The spread of instant messenger systems provides an excellent opportunity and a helpful tool to healthcare professionals. WhatsApp instant messenger use is widely prevalent among health professionals, cancer patients, caregivers and the general population. It is a quick and easy communication tool that may also be used on personal computers and business purposes. WhatsApp instant messenger and other similar tools may be a very useful complement for e-medicine. Instant messaging systems may be helpful, especially in rural areas, in medium- or low-income countries, or to avoid unnecessary travels, improve knowledge and awareness of cancer, monitor home care and support the delivery of home ca…

Maddalena Opioid Switching Score in patients with cancer pain

2021

Evaluation of opioid switching (OS) for cancer pain has not been properly assessed. The aim of this study was to assess an integrated score (Maddalena Opioid Switching Score) as a simple and repeatable tool to evaluate the outcomes of OS, facilitating the interpretation and comparison of studies, and information exchange among researchers. The integrated score took into account pain intensity, intensity of opioid-related symptoms, and cognitive function by using an author's formula. Physical and psychological symptoms were evaluated by the Edmonton Symptom Assessment Scale and Patient Global Impression (PGI) by the minimal clinically important difference. One hundred six patients were analy…

Wages, Work, and the Catholic Social Teaching

2021

The Catholic Social Teaching is a rich and relevant source for studying contemporary problems in society. In this paper, I investigate the question about equal pay in light of the social teaching. During the last decade, there has been an increasing interest in equal pay and related concepts like universal basic income. By equal pay we mean that everyone in society receives the same remuneration regardless of the type of work, level of effort, or unemployed or not. From an economic point of view, there are large negative incentive effects with such an arrangement. The reason is that the principle of ‘equal pay for all’ breaks the relationship between the workers’ effort and the payment asso…

The relationships among motivational climate, perceived competence, physical performance, and affects during physical education fitness testing lesso…

2021

Despite the prominence of fitness testing in school physical education (PE), there is a sparsity of research examining the antecedents of students’ affective experiences during fitness testing lessons. This study aimed to investigate the associations among task- and ego-involving motivational climates, perceived physical competence, physical performance, enjoyment, and anxiety during two different types of PE fitness testing lessons. Altogether, 645 Finnish students from Grade 5 (50% boys, Mage = 11.2, SD = 0.36) and Grade 8 (47% boys, Mage = 14.2, SD = 0.35) participated in two fitness testing lessons with different content (lesson 1: 20-meter shuttle run test and a test of flexibility; l…

Geodynamic Modeling with Uncertain Initial Geometries

2021

Mediterranean, DASH, and MIND dietary patterns and cognitive function: The 2-year longitudinal changes in an older Spanish cohort

2021

Wu, L., and Sun, D. (2017). Adherence to Mediterranean diet and risk of developing cognitive disorders: an updated systematic review and meta-analysis of prospective cohort studies. Sci. Rep. 7:41317. doi: 10.1038/srep41317 Wu, Z., Phyo, A. Z. Z., Al-harbi, T., Woods, R. L., and Ryan, J. (2020). Distinct cognitive trajectories in late life and associated predictors and outcomes: a systematic review. J. Alzheimer’s Dis. Rep. 4, 459–478. doi: 10.3233/ADR-200232 Conflict of Interest: SKN was a volunteer member of the not-for profit group Plant Based Canada. JS-S reported receiving research support from the Instituto de Salud Carlos III, Ministerio de Educación y Ciencia, Departament de Salut P…

Negative responses to strategic innovation, a case study of record labels facing streaming

2021

Record labels are organizations in charge of phonographic production at the interface between musicians and the audience. Since the arrival of digital technologies such as the mp3 and the Internet, record labels have had to adapt to several changes: wider distribution channels, dematerialized competitors, customers’ demands for free music, more ephemeral cooperation. Specifically, streaming platforms like Spotify brought a major change known as a strategic innovation. A strategic innovation is a strong change that overturns all previously established values in the sector (renewal of values attached to the product, values attached to the customer relationship and power relations). However, f…

Testing effects of Lorentz invariance violation in the propagation of astroparticles with the Pierre Auger Observatory

2021

The successful installation, commissioning, and operation of the Pierre Auger Observatory would not have been possible without the strong commitment and effort from the technical and administrative staff in Malargüe. We are very grateful to the following agencies and organizations for financial support: Argentina — Comisión Nacional de Energía Atómica; Agencia Nacional de Promoción Científica y Tecnológica (ANPCyT); Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET); Gobierno de la Provincia de Mendoza; Municipalidad de Malargüe; NDM Holdings and Valle Las Leñas; in gratitude for their continuing cooperation over land access; Australia — the Australian Research Council; Be…

Magnomechanics in suspended magnetic beams

2021

Cavity optomechanical systems have become a popular playground for studies of controllable nonlinear interactions between light and motion. Owing to the large speed of light, realizing cavity optomechanics in the microwave frequency range requires cavities up to several mm in size, hence making it hard to embed several of them on the same chip. An alternative scheme with much smaller footprint is provided by magnomechanics, where the electromagnetic cavity is replaced by a magnet undergoing ferromagnetic resonance, and the optomechanical coupling originates from magnetic shape anisotropy. Here, we consider the magnomechanical interaction occurring in a suspended magnetic beam -- a scheme in…

Developing a programme theory for the Systemic Practice Model in children's social care : Key informants' perspectives

2021

Vague programme descriptions are known to impede implementation and evaluation. Yet social work change programmes often fail to describe in detail how they aim to provide better outcomes for children and families. This study focused on the Systemic Practice Model (SPM), which is a Finnish adaptation of Reclaiming Social Work, a practice model developed in England. The SPM aims to deliver systemic practice in children's social care and has recently been widely disseminated across Finland. However, research has found both considerable variation in its delivery and a lack of clarity about what it is. This study, applying realist evaluation, aimed to formulate a programme theory based on the pe…

Gastromania on italian tv

2021

By turning on the TV, at any time of the day or night, one can comeacross programs in which food is the undisputed protagonist. Actually, thepresence of food on TV is not a contemporary phenomenon, but it goesback to the origins of television. Over time, the way of narrating food hasbeen transformed, as well as the role attributed to it and the values (gastronomicand social) associated to it.In this paper, after having traced a historical overview of Italian foodtelevision programming, we focus on the analysis of four recent programs.The objective is to understand how settings, rhythmic and temporal scansion,and the distribution of roles among the various actors involved configurenarratives…

Subduction Polarity Reversal Triggered by Oceanic Plateau Accretion: Implications for Induced Subduction Initiation

2021

Aproximación al estudio de la negligencia parental y sus efectos en la infancia y adolescencia

2021

El presente trabajo recoge una aproximación conceptual del término negligencia, su incidencia, etiología y consecuencias en el neurodesarrollo,  así como el estudio con una muestra de 176  niños, niñas y adolescentes en situación de riesgo derivados desde los Servicios Sociales de Base a un recurso especializado de atención a la infancia y adolescencia en situación de vulnerabilidad, en Declaración de Riesgo o con Medida Jurídica de Protección. El propósito general fue profundizar en el estudio de la Negligencia Familiar. A tal fin y con una metodología descriptiva y exploratoria se procedió al uso de pruebas autoinformadas, evaluación de la familia y evaluación del tutor/a desde el área es…

Effect of Space charge accumulation inside the thermoplastic insulation of a loaded HVDC model cable

2021

The space charge accumulation phenomenon represents one of the main degradation factors for the dielectrics employed in the field of the HVDC transmission. For this reason, the recommendation IEEE Std 1732-2017 has been proposed. In that standard, due to the importance attributed at the space charge phenomenon, the experts suggest the introduction of the space charge measurement in HVDC cables during the prequalification or type tests, by means of the PEA method. However, despite for tests in flat specimens the PEA technique is well consolidated, for cable specimens difficulties are still present. In particular, the PEA cell output signal is strongly conditioned by the arranged measurement …

Birth weight, adult weight, and cardiovascular biomarkers : Evidence from the Cardiovascular Young Finns Study

2021

This study quantifies the causal effect of birth weight on cardiovascular biomarkers in adulthood using the Cardiovascular Risk in Young Finns Study (YFS). We apply a multivariable Mendelian randomization (MVMR) method that provides a novel approach to improve inference in causal analysis based on a mediation framework. The results show that birth weight is linked to triglyceride levels (β = −0.294; 95% CI [−0.591, 0.003]) but not to low-density lipoprotein (LDL) cholesterol levels (β = 0.007; 95% CI [−0.168, 0.183]). The total effect of birth weight on triglyceride levels is partly offset by a mediation pathway linking birth weight to adult BMI (β = 0.111; 95% CI [−0.013, 0.234]). The nega…

Partial discharges characteristics during load transients in an HVDC model cable

2021

The occurrence of Partial Discharges (PD) in HVAC cables is widespread considered as one of the most important concerns for the stability of the insulation. To date, the role of PD in the ageing and definitive fault of HVDC cables has been poorly investigated. This is mainly due to some practical difficulties in the performing of the measurements. Compared to the PDs occurring under AC stress, the higher inception voltages and the lower repetition rates, obtainable under DC voltage, make the exclusion of the measurement noise more difficult. This paper is focused on the study of the characteristics of the PDs occurring in an artificial defect located in proximity of the outer dielectric' su…

Scleral Buckling: A Review of Clinical Aspects and Current Concepts

2021

Scleral buckling represents a valuable treatment option for rhegmatogenous retinal detachment repair. The surgery is based on two main principles: the closure of retinal breaks and the creation of a long-lasting chorioretinal adhesion. Buckles are placed onto the sclera with the purpose of sealing retinal breaks. Cryopexy is usually performed to ensure a long-lasting chorioretinal adhesion. Clinical outcomes of scleral buckling have been shown to be more favorable in phakic eyes with uncomplicated or medium complexity retinal detachment, yielding better anatomical and functional results compared with vitrectomy. Several complications have been described following scleral buckling surgery, s…

Rational solutions to the KdV equation depending on multi-parameters

2021

We construct multi-parametric rational solutions to the KdV equation. For this, we use solutions in terms of exponentials depending on several parameters and take a limit when one of these parameters goes to 0. Here we present degenerate rational solutions and give a result without the presence of a limit as a quotient of polynomials depending on 3N parameters. We give the explicit expressions of some of these rational solutions.

Transient frailty induced by cell division. Observation, reasons and implications

2021

We know that stress-factors, e.g. X-rays, have an effect on cells that is more lethal in rapid exponential growth than in stationary phase. It is this effect which makes radiotherapy effective in cancer treatment. This stress effect can be explained in two ways: (a) more vulnerability in the growth phase, (b) improved protection capacity and repair mechanisms in the stationary phase. Although the two explanations do not exclude each other, they are very different in the sense that (a) is a general mechanism whereas (b) is strain and stress-factor dependent. In this paper we explore major facets of (a). Firstly, we emphasize that (a) can account for known experimental stress-factor evidence.…

Multi-proxy analysis suggests Late Pleistocene affinities of human skeletal remains attributed to Balzi Rossi

2021

: In two publications from 1967 and 1971, M. Masali described human skeletal remains presumed to have been found in the Balzi Rossi caves (Ventimiglia, Italy), based on a signed note dated to 1908. Since then, the remains - dubbed "Conio's Finds" and preserved at the University of Torino - had not been further studied. We performed a multidisciplinary investigation aimed at clarifying the geographical and chronological attribution of these specimens. Collagen extraction for AMS dating was unsuccessful, but we obtained two direct dates on the best- preserved crania via 231Pa/235U direct gamma-ray spectrometry (10,500±2,000 years BP and 12,500±2,500 years BP). We analyzed the metrics and morp…

Tuffarsi nel visivo/Recensione Alla soglia dell’immagine di Andrea Pinotti

2021

Recensione al libro di Andrea Pinotti, "Alla soglia dell’immagine" (Einaudi). Attraversando una vasta costellazione di casi che dalla cultura visuale antica arriva ai contemporanei dispositivi immersivi di realtà virtuale, Pinotti propone un’analisi critica di quelle immagini che si caratterizzano per il fatto di negare il loro stesso statuto iconico. Un’an-iconologia, dunque, che intrecciandosi con l’archeologia dei media si pone il problema di quale sia l’effetto di questo duplice movimento del nostro ingresso nel mondo virtuale dell’immagine e di esondazione di elementi del mondo iconico in quello reale.

A new Framework for the Spectral Information Decomposition of Multivariate Gaussian Processes

2021

: Different information-theoretic measures are available in the literature for the study of pairwise and higher-order interactions in multivariate dynamical systems. While these measures operate in the time domain, several physiological and non-physiological systems exhibit a rich oscillatory content that is typically analyzed in the frequency domain through spectral and cross-spectral approaches. For Gaussian systems, the relation between information and spectral measures has been established considering coupling and causality measures, but not for higher-order interactions. To fill this gap, in this work we introduce an information-theoretic framework in the frequency domain to quantify t…

« Stadien-Namen in der Sponsoring-Ära: ein patternbasierter Ansatz zur Analyse von Stadien-Namen in vier europäischen Sprachen »

2021

International audience