Search results for " α"

showing 10 items of 85 documents

Catalytic Enantioselective Addition of Me2Zn to Isatins

2017

Chiral α-hydroxyamide L5 derived from (S)-(+)-mandelic acid catalyzes the enantioselective addition of dimethylzinc to isatins affording the corresponding chiral 3-hydroxy-3-methyl-2-oxindoles with good yields and er up to 90:10. Furthermore, several chemical transformations were performed with the 3-hydroxy-2-oxindoles obtained.

Dimethylzincchemistry.chemical_elementZinc010402 general chemistrylcsh:Chemical technology01 natural sciencesisatinCatalysisCatalysislcsh:Chemistrychemistry.chemical_compoundchiral α-hydroxyamide3-hydroxyoxindoleCatàlisilcsh:TP1-1185Physical and Theoretical Chemistry010405 organic chemistryChemistryIsatinzincEnantioselective synthesisasymmetric catalysisCombinatorial chemistry0104 chemical scienceslcsh:QD1-999mandelamidesQuímica orgànica
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The effect of the comonomer on the copolymerization of ethylene with long chain α-olefins using Ziegler–Natta catalysts supported on MgCl2(THF)2

2000

Abstract The effect of the type of the comonomer (1-pentene, 1-hexene, 1-octene, 1-decene and 1-dodecene) on the copolymerization of ethylene with α-olefin over vanadium (VOCl3 and VCl4) and titanium (TiCl4) catalysts supported on MgCl2(THF)2 and activated by Et2AlCl was studied. The results show that the introduction of a longer α-olefin in the ethylene polymerization feed depresses the catalytic activity of all investigated catalysts. The catalyst activity does not depend on the type of the comonomer applied but changes with the comonomer concentration in the feed. The incorporation of α-olefin in the polymer chain was found to be dependent on the type and concentration of the comonomer i…

EthyleneMaterials scienceCopolymerization of ethylene with α-olefinPolymers and PlasticsComonomerOrganic ChemistryCatalysischemistry.chemical_compoundCrystallinityVanadium catalystPolymerizationchemistryPolymer chemistryMaterials ChemistryCopolymerZiegler–Natta catalystOcteneTitanium catalystPolymer
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Prédiction de la réponse aux traitements de fond antirhumatismaux (DMARD) dans la polyarthrite rhumatoïde

2010

Resume Objectif Examiner les facteurs potentiels predictifs de la reponse aux traitements de fond (DMARD) classiques dans la polyarthrite rhumatoide (PR). Methodes (1) design de l’etude : etude prospective sur six mois de suivi. Participants  : patients avec une PR active ; (2) intervention et suivi : introduction d’un DMARD. Reponse au traitement evaluee a six mois (criteres ACR20) ; (3) analyse : facteurs potentiels predictifs de la reponse : criteres demographiques, activite de la maladie, pourcentages de sous-populations de cellules mononucleees du sang peripherique (CMSP) exprimant la glycoproteine P, taux d’interleukine 1 beta (IL-1β) serique, IL-6, IL-8, IL-10, IL-12 et de facteur de…

Gynecologymedicine.medical_specialtyRheumatologybusiness.industryMedicinebusinessTumor necrosis factor αRevue du Rhumatisme
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Interferon-α for HBeAg-positive chronic hepatitis B

2004

HBEAG POSITIVEHepatologybusiness.industrymedicine.medical_treatmentInterferon-alphaAlpha interferonImmunotherapyHepatitis Bmedicine.diseaseAntiviral AgentsVirologyHepatitis B ChronicChronic hepatitisInterferon αImmunologyHumansMedicineHepatitis B e AntigensViral diseasebusinessInterferon alfamedicine.drug
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PRELIMINARY STUDY ON QUANTIFICATION OF aS1-CASEIN VARIANTS IN GIRGENTANA GOAT BREED BY DIRECT CHROMATOGRAPHIC ANALYSIS OF MILK

2012

Goat αs1-casein is a highly polymorphic protein, coded by CSN1S1 gene. Nowadays, several alleles were identified and associated with different levels of αs1-casein in goat milk. Polymorphisms at αs1-casein locus have been shown to affect not only the quantity of this casein in goat milk, but also the structural and nutritional characteristics (hypoallergenic properties) and technological properties of the milk (1). The aim of this work was to separate and quantify the most common allelic variants of αs1-casein in milk of Girgentana goat breed, a Sicilian autochthonous breed, and to evaluate the effect of αs1-casein polymorphisms on casein content. The CSN1S1 A/01, B/E, F, and N alleles were…

HPLC genetic variants αs1-casein goat’s milk
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Effects of tumor necrosis factor-alpha on tumor blood flow and hyperthermic treatment.

1989

The impact of recombinant human tumor necrosis factor-alpha (rhTNF-alpha), given alone or in combination with local hyperthermia, on perfusion and growth of a moderately rhTNF-alpha-sensitive rat tumor (DS-carcinosarcoma) was investigated. DS-carcinosarcomas were implanted into the hind foot dorsum of Sprague-Dawley rats. Tumor blood flow (TBF) was measured with the krypton-85 clearance technique. Treatment with either tumor necrosis factor-alpha (0.1-1.0 mg/kg) or hyperthermia (43.3 and 44.3 degrees C, 40 min) can decrease the perfusion of malignant tumors. The TBF reduction was fully established 2 h after rhTNF-alpha injection and lasted for at least 4 h. The application of local hyperthe…

HyperthermiaCancer ResearchNecrosisSoft Tissue NeoplasmsPharmacologyCarcinosarcomaTumor perfusionmedicineAnimalsTumor growthTumor necrosis factor αbusiness.industryTumor Necrosis Factor-alphaRats Inbred StrainsHematologyBlood flowHyperthermia Inducedmedicine.diseaseCombined Modality TherapyRecombinant ProteinsRatsOncologyRegional Blood FlowImmunologyTumor necrosis factor alphamedicine.symptombusinessPerfusionCell DivisionNeoplasm TransplantationOnkologie
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Interferon-α as an Antagonist to Proinflammatory and Hematopoietic Cytokines

1994

Inflammationbusiness.industryImmunologyAntagonistInterferon-alphaBone Marrow CellsHematopoietic Stem CellsProinflammatory cytokineHaematopoiesisBone MarrowVirologyInterferon αImmunologyCytokinesHumansMedicineStromal CellsbusinessJournal of Interferon Research
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Document Word Clouds: Visualising Web Documents as Tag Clouds to Aid Users in Relevance Decisions

2009

Περιέχει το πλήρες κείμενο Information Retrieval systems spend a great effort on determining the significant terms in a document. When, instead, a user is looking at a document he cannot benefit from such information. He has to read the text to understand which words are important. In this paper we take a look at the idea of enhancing the perception of web documents with visualisation techniques borrowed from the tag clouds of Web 2.0. Highlighting the important words in a document by using a larger font size allows to get a quick impression of the relevant concepts in a text. As this process does not depend on a user query it can also be used for explorative search. A user study showed, th…

Information retrievalProcess (engineering)Computer sciencemedia_common.quotation_subjectDocument clusteringUser requirements documentWorld Wide WebPerceptionRelevance (information retrieval)Tag cloudtf–idfΤεχνικές υπηρεσίες σε βιβλιοθήκες αρχεία και μουσείαTechnical services in libraries archives and museumsWord (computer architecture)media_common
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Abnormalities in serum concentrations of interleukin-2, interferon-alpha and interferon-gamma in schizophrenia not detected.

1992

The hypothesis of an immunological defect in schizophrenia has been supported by reports on abnormal production of interleukin-2 (IL-2) and interferons (IFNs) in schizophrenic patients. In the present study we determined the serum concentrations of IL-2, IFN-alpha and IFN-gamma in 10 first onset, neuroleptic-naive schizophrenics, in 6 pretreated patients who were drug free (1 week to 2 years) at the time of the investigation and in 15 matched healthy controls. No IFN-alpha was detected in schizophrenics' and in control sera. No differences were found in IL-2 and IFN-gamma levels between schizophrenics and controls. Thus the present study failed to support the hypothesis of an immunological …

Interleukin 2AdultMalePsychosisAlpha interferonInterferon-gammaReference ValuesInterferon αmedicineImmune ToleranceHumansInterferon gammaBiological PsychiatryInterferon alfaPsychiatric Status Rating ScalesSchizophrenia Paranoidbusiness.industryInterferon-alphaSerum concentrationmedicine.diseasePsychiatry and Mental healthSchizophreniaImmunologySchizophreniaInterleukin-2FemaleSchizophrenic Psychologybusinessmedicine.drugSchizophrenia research
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Development of oil cysts after subcutaneous injection of interferon-α and interleukin-2

2006

Interleukin 2Pathologymedicine.medical_specialtybusiness.industryAlpha interferonDermatologyInterleukine 2Subcutaneous injectionInterferon αToxicityMedicinebusinessInterferon alfamedicine.drugBritish Journal of Dermatology
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