Search results for " Integra"

showing 10 items of 2527 documents

Vector Autoregressive Fractionally Integrated Models to Assess Multiscale Complexity in Cardiovascular and Respiratory Time Series

2020

Cardiovascular variability is the result of the activity of several physiological control mechanisms, which involve different variables and operate across multiple time scales encompassing short term dynamics and long range correlations. This study presents a new approach to assess the multiscale complexity of multivariate time series, based on linear parametric models incorporating autoregressive coefficients and fractional integration. The approach extends to the multivariate case recent works introducing a linear parametric representation of multiscale entropy, and is exploited to assess the complexity of cardiovascular and respiratory time series in healthy subjects studied during postu…

Multivariate statisticsvector autoregressive fractionally integrated (VARFI) modelComputer scienceQuantitative Biology::Tissues and OrgansPhysics::Medical Physicssystolic arterial pressure (SAP)Cardiovascular variabilitycomputer.software_genreCorrelationAutoregressive modelmultiscale entropy (MSE)heart period (HP)Settore ING-INF/06 - Bioingegneria Elettronica E InformaticaParametric modelMultiple timeEntropy (information theory)Data miningTime seriescomputerParametric statistics2020 11th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO)
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Mercosur entre mundialización y nacionalismos

2000

Versión corta e inédita del artículo "Mercosur y la otra mundialización" (en: El País, 5 de octubre de 2000) destinada a la Embajada de España en Paraguay.

MundializaciónMercado mundialMercosurVidal-Beneyto JoséMultinacionalesAlternativaAsociación Latinoamericana de IntegraciónEconomíaPublicaciones: Obra periodística: Columnas y artículos de opiniónLa otra mundializaciónUniformizaciónColegio de Altos Estudios EuropeosGlobalizaciónOMCLiberalizaciónOligopoliosFMIBanco MundialEmpresas transnacionalesTribunal SupremoPOLÍTICAOCDEForo Social MundialAbogadosG-7G-8ProgresoParadigma financieroPorto AlegreJUSTICIANuevas tecnologíasTeleinformaciónJueces
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Mercosur y la otra mundialización

2000

La versión publicada de este artículo aparece también en Cassen, Bernard, et al. (2002). Attac : contra la dictadura de los mercados : alternativas a la mundialización neoliberal (pp. 111-116). Barcelona: Icaria.

MundializaciónMercado mundialMercosurVidal-Beneyto JoséMultinacionalesAlternativaAsociación Latinoamericana de IntegraciónEconomíaPublicaciones: Obra periodística: Columnas y artículos de opiniónLa otra mundializaciónUniformizaciónColegio de Altos Estudios EuropeosGlobalizaciónOMCLiberalizaciónOligopoliosFMIBanco MundialEmpresas transnacionalesTribunal SupremoPOLÍTICAOCDEForo Social MundialAbogadosG-7G-8ProgresoParadigma financieroPorto AlegreJUSTICIANuevas tecnologíasTeleinformaciónJueces
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Drug connectivity mapping and functional analysis reveal therapeutic small molecules that differentially modulate myelination

2022

Disruption or loss of oligodendrocytes (OLs) and myelin has devastating effects on CNS function and integrity, which occur in diverse neurological disorders, including Multiple Sclerosis (MS), Alzheimer’s disease and neuropsychiatric disorders. Hence, there is a need to develop new therapies that promote oligodendrocyte regeneration and myelin repair. A promising approach is drug repurposing, but most agents have potentially contrasting biological actions depending on the cellular context and their dose-dependent effects on intracellular pathways. Here, we have used a combined systems biology and neurobiological approach to identify compounds that exert positive and negative effects on olig…

MyelinMiceMyelin SheathNSC Neural stem cellSystems BiologyOPC Oligodendrocyte progenitor cellHigh-Throughput Nucleotide SequencingLINCS The Library of Integrated Network-based Cellular SignaturesCell DifferentiationGeneral MedicineCNS Central Nervous SystemOligodendrogliamedicine.anatomical_structureOligodendrogenesisNFOL Newly formed oligodendrocyteOL OligodendrocyteSignal TransductionSubventricular zoneOptic nerveIn silicoSystems biologyMorpholinesSVZ subventricular zoneContext (language use)RM1-950BiologyArticlemedicinePharmacogenomics The Library of Integrated Network-Based Cellular Signatures/LINCSAnimalsH-LY29 High concentration of LY294002Computer SimulationPI3K/AKT/mTOR pathwayL-LY29 Low concentration of LY294002PharmacologyPI3K/AktTCN TriciribineDose-Response Relationship DrugRegeneration (biology)Multiple sclerosismedicine.diseaseOligodendrocyteOligodendrocyteiNSCs iPSC-derived NSCsTAPs Transiently amplifying progenitorsMice Inbred C57BLMS Multiple SclerosisiPCS induced Pluripotent Stem CellChromonesPharmacogeneticsTherapeutics. PharmacologyMOL Myelinating oligodendrocyteNeuroscienceBiomedicine & Pharmacotherapy
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Dendritic Ih selectively blocks temporal summation of unsynchronized distal inputs in CA1 pyramidal neurons.

2004

The active dendritic conductances shape the input-output properties of many principal neurons in different brain regions, and the various ways in which they regulate neuronal excitability need to be investigated to better understand their functional consequences. Using a realistic model of a hippocampal CA1 pyramidal neuron, we show a major role for the hyperpolarization-activated current, I-h, in regulating the spike probability of a neuron when independent synaptic inputs are activated with different degrees of synchronization and at different distances from the soma. The results allowed us to make the experimentally testable prediction that the I-h in these neurons is needed to reduce ne…

N-MethylaspartateTime FactorsComputer scienceCognitive NeuroscienceModels NeurologicalNeural ConductionHippocampal formationSummationHippocampusSynaptic TransmissionCA1Cellular and Molecular NeurosciencemedicineExcitatory Amino Acid AgonistsAnimalsComputer Simulationalpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic AcidI-hProbabilityCa1 pyramidal neuronPyramidal CellsExcitatory Postsynaptic PotentialsReproducibility of ResultsmodelingDendritesSensory Systemsdendritic integrationmedicine.anatomical_structurenervous systemSomaNeuronNeuroscience
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EVALUATION OF THE COMBINED EFFECT OF VEGETATION AND NATURAL VENTILATION IN NEARLY ZERO ENERGY MULTI-STOREY BUILDINGS – nZE(ms)B

2020

Cooling load is the main cause of high energy consumption for tall buildings in tropical climates while the construction of tall buildings is an unavoidable practice due to land scarcity in metropolitan cities. In this regard, the use of natural ventilation (NV) in tall buildings can help reducing the energy consumption. However, this solution can also bring the problem of polluted air that may enter the space to be ventilated. If the air is passed through a system that can absorb pollutants and add more oxygen to the air, the problem may almost be solved. Building integrated vegetation (BIV) systems can help solving this problem. So, if the air entering buildings passes through dense veget…

NEARLY ZERO ENERGY MULTI-STOREY BUILDINGSComputational DesignComputational Fluid DynamicBuilding Integrated VegetationNatural Ventilation
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Deformations of the seventh order Peregrine breather solutions of the NLS equation with twelve parameters.

2013

We study the solutions of the one dimensional focusing NLS equation. Here we construct new deformations of the Peregrine breather of order 7 with 12 real parameters. We obtain new families of quasi-rational solutions of the NLS equation. With this method, we construct new patterns of different types of rogue waves. We recover triangular configurations as well as rings isolated. As already seen in the previous studies, one sees appearing for certain values of the parameters, new configurations of concentric rings.

NLS equationAkhmediev's solutions.Nonlinear Sciences::Exactly Solvable and Integrable Systems[MATH.MATH-MP]Mathematics [math]/Mathematical Physics [math-ph]Peregrine breathers[ MATH.MATH-MP ] Mathematics [math]/Mathematical Physics [math-ph]Akhmediev's solutions[MATH.MATH-MP] Mathematics [math]/Mathematical Physics [math-ph]Nonlinear Sciences::Pattern Formation and Solitons
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Deformations of third order Peregrine breather solutions of the NLS equation with four parameters

2013

In this paper, we give new solutions of the focusing NLS equation as a quotient of two determinants. This formulation gives in the case of the order 3, new deformations of the Peregrine breather with four parameters. This gives a very efficient procedure to construct families of quasi-rational solutions of the NLS equation and to describe the apparition of multi rogue waves. With this method, we construct the analytical expressions of deformations of the Peregrine breather of order N=3 depending on $4$ real parameters and plot different types of rogue waves.

NLS equationAkhmediev's solutions.Nonlinear Sciences::Exactly Solvable and Integrable Systems[MATH.MATH-MP]Mathematics [math]/Mathematical Physics [math-ph]WronskiansPeregrine breathers[ MATH.MATH-MP ] Mathematics [math]/Mathematical Physics [math-ph]Riemann theta functionsAkhmediev's solutions[MATH.MATH-MP] Mathematics [math]/Mathematical Physics [math-ph]Nonlinear Sciences::Pattern Formation and SolitonsFredholm determinants
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Six-parameters deformations of fourth order Peregrine breather solutions of the NLS equation.

2013

We construct solutions of the focusing NLS equation as a quotient of two determinants. This formulation gives in the case of the order 4, new deformations of the Peregrine breather with 6 real parameters. We construct families of quasi-rational solutions of the NLS equation and describe the apparition of multi rogue waves. With this method, we construct the analytical expressions of deformations of the Peregrine breather of order 4 with 6 real parameters and plot different types of rogue waves.

NLS equationAkhmediev's solutions.Nonlinear Sciences::Exactly Solvable and Integrable Systemswronskians[MATH.MATH-MP]Mathematics [math]/Mathematical Physics [math-ph]Fredohlm determinantsPeregrine breathers[ MATH.MATH-MP ] Mathematics [math]/Mathematical Physics [math-ph]Riemann theta functionsAkhmediev's solutions[MATH.MATH-MP] Mathematics [math]/Mathematical Physics [math-ph]Nonlinear Sciences::Pattern Formation and Solitons
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Families of deformations of the thirteen peregrine breather solutions to the NLS equation depending on twenty four parameters

2017

International audience; We go on with the study of the solutions to the focusing one dimensional nonlinear Schrodinger equation (NLS). We construct here the thirteen's Peregrine breather (P13 breather) with its twenty four real parameters, creating deformation solutions to the NLS equation. New families of quasirational solutions to the NLS equation in terms of explicit ratios of polynomials of degree 182 in x and t multiplied by an exponential depending on t are obtained. We present characteristic patterns of the modulus of these solutions in the (x; t) plane, in function of the different parameters.

NLS equationNonlinear Sciences::Exactly Solvable and Integrable SystemsPeregrine breather[MATH.MATH-MP]Mathematics [math]/Mathematical Physics [math-ph]MSC: 35Q55 37K10Rogue waves[ MATH.MATH-MP ] Mathematics [math]/Mathematical Physics [math-ph][MATH.MATH-MP] Mathematics [math]/Mathematical Physics [math-ph]Nonlinear Sciences::Pattern Formation and Solitons
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