Search results for " Interference"
showing 10 items of 340 documents
The Dorsocross T-box transcription factors promote tissue morphogenesis in the Drosophila wing imaginal disc.
2012
The Drosophila wing imaginal disc is subdivided into notum, hinge and blade territories during the third larval instar by formation of several deep apical folds. The molecular mechanisms of these subdivisions and the subsequent initiation of morphogenic processes during metamorphosis are poorly understood. Here, we demonstrate that the Dorsocross (Doc) T-box genes promote the progression of epithelial folds that not only separate the hinge and blade regions of the wing disc but also contribute to metamorphic development by changing cell shapes and bending the wing disc. We found that Doc expression was restricted by two inhibitors, Vestigial and Homothorax, leading to two narrow Doc stripes…
Secondary users selection and sparse narrow-band interference mitigation in cognitive radio networks
2018
Spectrum scarcity is a critical problem that may reduce the effectiveness of wireless technologies and services. To address this problem, different spectrum management techniques have been proposed in the literature such as overlay cognitive radio (CR) where the unlicensed users can share the same spectrum with the licensed users. The main challenges in overlay CR networks are the identification and detection of the Primary User (PU) signals in a multi-source narrow-band interference (NBI) scenario. Therefore, in this paper, we investigate the performance of an orthogonal frequency division multiplexing (OFDM) overlay CR network with Secondary Users (SUs) and subcarriers selection schemes. …
Filtering out intersymbol interference in spread-spectrum communication systems
1979
In this letter the transfer characteristic of the optimum filter suitable for eliminating intersymbol interference in pseudo-noise spread-spectrum communication systems is determined. Such a characteristic is independent of the code sequence employed.
Demo abstract: Cross-technology TDMA synchronization using energy pattern beacons
2017
When different technologies use the same frequency bands in close proximity, the resulting interference typically results in performance degradation. Coexistence methods exist, but these are often technology specific and require technology specific interference detection methods. To remove the root cause of the performance degradation, devices should be able to negotiate medium access even when using different technologies. To this end, an architecture that allows cross-technology medium access by means of a Time Division Multiple Access (TDMA) scheme was devised. In order to achieve cross-technology synchronization, which is required for the TDMA solution, an energy pattern beacon is trans…
Cigarette smoke increases BLT2 receptor functions in bronchial epithelial cells: in vitro and ex vivo evidence
2013
Summary Leukotriene B4 (LTB4) is a neutrophil chemotactic molecule with important involvement in the inflammatory responses of chronic obstructive pulmonary disease (COPD). Airway epithelium is emerging as a regulator of innate immune responses to a variety of insults including cigarette smoke, the major risk factor for COPD. In this study we have explored whether cigarette smoke extracts (CSE) or soluble mediators present in distal lung fluid samples (mini-bronchoalveolar lavages) from smokers alter the expression of the LTB4 receptor 2 (BLT2) and peroxisome proliferator-activated receptor-α (PPAR-α) in bronchial epithelial cells. We also evaluated the effects of CSE on the expression of i…
HSP27 controls GATA-1 protein level during erythroid cell differentiation.
2010
AbstractHeat shock protein 27 (HSP27) is a chaperone whose cellular expression increases in response to various stresses and protects the cell either by inhibiting apoptotic cell death or by promoting the ubiquitination and proteasomal degradation of specific proteins. Here, we show that globin transcription factor 1 (GATA-1) is a client protein of HSP27. In 2 models of erythroid differentiation; that is, in the human erythroleukemia cell line, K562 induced to differentiate into erythroid cells on hemin exposure and CD34+ human cells ex vivo driven to erythroid differentiation in liquid culture, depletion of HSP27 provokes an accumulation of GATA-1 and impairs terminal maturation. More spec…
eNOS S-nitrosylates β-actin on Cys374 and regulates PKC-θ at the immune synapse by impairing actin binding to profilin-1.
2017
The actin cytoskeleton coordinates the organization of signaling microclusters at the immune synapse (IS); however, the mechanisms involved remain poorly understood. We show here that nitric oxide (NO) generated by endothelial nitric oxide synthase (eNOS) controls the coalescence of protein kinase C-¿ (PKC-¿) at the central supramolecular activation cluster (c-SMAC) of the IS. eNOS translocated with the Golgi to the IS and partially colocalized with F-actin around the c-SMAC. This resulted in reduced actin polymerization and centripetal retrograde flow of ß-actin and PKC-¿ from the lamellipodium-like distal (d)-SMAC, promoting PKC-¿ activation. Furthermore, eNOS-derived NO S-nitrosylated ß-…
New circuital models of grounding systems and PDS for EMI analysis during a lightning strike
2005
In this paper circuital models of a Power Drive System (PDS) and of grounding systems are proposed in order to analyse Electromagnetic Interferences (EMI) induced in a PDS when a lightning current flows in the grounding system. The models have been developed adopting the network approach with lumped parameters and have been implemented using the software MATLAB. A High Frequency (HF) model suitable to simulate the impulse response of a PDS is described and a generalized method in order to calculate the lumped parameters values of grounding system models is presented. The new method takes into account the burial depth of electrodes as regards their length. The validation results of this new …
Resveratrol decreases the levels of miR-155 by upregulating miR-663, a microRNA targeting JunB and JunD.
2010
An inflammatory component is present in the microenvironment of most neoplastic tissues, including those not causally related to an obvious inflammatory process. Several microRNAs, and especially miR-155, play an essential role in both the innate and adaptative immune response. Resveratrol (trans-3,4#,5-trihydroxystilbene) is a natural antioxidant with anti-inflammatory properties that is currently at the stage of preclinical studies for human cancer prevention. Here, we establish that, in human THP-1 monocytic cells as well as in human blood monocytes, resveratrol upregulates miR- 663, a microRNA potentially targeting multiple genes implicated in the immune response. In THP-1 cells, miR-66…
Impact of LoRa Imperfect Orthogonality: Analysis of Link-Level Performance
2018
In this letter, we focus on the evaluation of link-level performance of LoRa technology, in the usual network scenario with a central gateway and high-density deployment of end-devices. LoRa technology achieves wide coverage areas, low power consumption and robustness to interference thanks to a chirp spread-spectrum modulation, in which chirps modulated with different spreading factors (SFs) are quasi-orthogonal. We focus on the performance analysis of a single receiver in presence of collisions. First, we analyze LoRa modulation numerically and show that collisions between packets modulated with different SFs can indeed cause packet loss if the interference power received is strong enough…