Search results for " LAB"
showing 10 items of 2393 documents
Comparison between Rapid Intraoperative and Central Laboratory Parathormone Dosage in 12 Kidney Transplant Candidates
2016
Abstract Background The rapid intraoperative parathormone (PTH) and at central laboratory PTH dosage gives similar results. The central laboratory provides results in longer times and higher costs. Intraoperative measurement can reduce time and costs during parathyroidectomy. Methods Twelve patients undergoing parathyroidectomy for hyperparathyroidism renal transplant candidates were included. Diagnosis was made by laboratory tests (serum calcium, PTH) and imaging techniques (ultrasonography and scintigraphy). All patients presented PTH levels of >400 pg/mL (the limit value to be maintained in list for kidney transplantation) and resistant to medical therapy. For each patient, 2 blood sampl…
Vidusskolēnu interpunkcijas un ortogrāfijas prasmes: problēmas un risinājuma iespējas
2019
Praksē vērojams, ka daudzu vidusskolēnu pareizrakstības prasmes ir nepilnīgas, kas liecina, ka pamatskolā nav attīstītas nepieciešamās iemaņas. Spilgti izpaužas tas, ka vidusskolēniem trūkst prasmes analizēt un izkopt rakstveida runu. Lingvodidaktikā relatīvi maz pētītas vidusskolēnu pareizrakstības prasmju pilnveidošanas iespējas, tādēļ maģistra darba mērķis ir izpētīt vidusskolēnu interpunkcijas un ortogrāfijas prasmi un piedāvāt paņēmienus tās pilnveidošanai. Tika veikts gadījuma pētījums un izmantotas datu vākšanas metodes – vidusskolēnu tekstveides darbu analīze, skolotāju intervijas un skolēnu pašvērtējumu analīze. Pētījumā noskaidrotas vidusskolēnu tipiskās pareizrakstības kļūdas, ef…
Beneficial Read-Through of aUSH1CNonsense Mutation by Designed Aminoglycoside NB30 in the Retina
2010
PURPOSE. The human Usher syndrome (USH) is the most frequent cause of inherited combined deaf-blindness. USH is clinically and genetically heterogeneous, assigned to three clinical types. The most severe type is USH1, characterized by profound inner ear defects and retinitis pigmentosa. Thus far, no effective treatment for the ophthalmic component of USH exists. The p.R31X nonsense mutation in USH1C leads to a disease causing premature termination of gene translation. Here, we investigated the capability of the novel synthetic aminoglycoside NB30 for the translational read-through of the USH1C-p.R31X nonsense mutation as a retinal therapy option. METHODS. Read-through of p.R31X by three com…
Processi partecipativi,pratiche urbane e progett-azione
2011
Una delle più interessanti esperienze di partecipazione ai processi di trasformazione urbanistica degli ultimi anni in Italia è quella condotta a Roma in occasione della presentazione del nuovo PRG nel 2003. Le associazioni del centro storico, ed in particolare quelle del Rione dei Monti, avviarono un processo di discussione e di informazione-azione che coinvolgeva cittadini, università, tecnici, enti locali e vari altri protagonisti dello scenario urbano. Il professore Carlo Cellamare, docente di urbanistica presso la facoltà di ingegneria dell'Università "La Sapienza" di Roma, è stato uno dei promotori di tale iniziativa, ed ha trattato i temi ad essa correlati nel seminario tenuto al Dip…
Next Generation Search for Axion and ALP Dark Matter with the International Axion Observatory
2018
International audience; More than 80 years after the postulation of dark matter, its nature remains one of the fundamental questions in cosmology. Axions are currently one of the leading candidates for the hypothetical, non-baryonic dark matter that is expected to account for about 25% of the energy density of the Universe. Especially in the light of the Large Hadron Collider at CERN slowly closing in on Weakly-Interacting Massive Particle (WIMP) searches, axions and axion-like particles (ALPs) provide a viable alternative approach to solving the dark matter problem. The fact that makes them particularly appealing is that they were initially introduced to solve a long-standing problem in qu…
Rosenbluth Separation of the π^{0} Electroproduction Cross Section.
2016
We present deeply virtual $\pi^0$ electroproduction cross-section measurements at $x_B$=0.36 and three different $Q^2$--values ranging from 1.5 to 2 GeV$^2$, obtained from experiment E07-007 that ran in the Hall A at Jefferson Lab. The Rosenbluth technique was used to separate the longitudinal and transverse responses. Results demonstrate that the cross section is dominated by its transverse component, and thus is far from the asymptotic limit predicted by perturbative Quantum Chromodynamics. An indication of a non-zero longitudinal contribution is provided by the interference term $\sigma_{LT}$ also measured. Results are compared with several models based on the leading twist approach of G…
First measurement of the muon neutrino charged current single pion production cross section on water with the T2K near detector
2017
The T2K off-axis near detector, ND280, is used to make the first differential cross section measurements of muon neutrino charged current single positive pion production on a water target at energies ∼0.8 GeV. The differential measurements are presented as a function of the muon and pion kinematics, in the restricted phase space defined by pπ+>200 MeV/c, pμ>200 MeV/c, cos(θπ+)>0.3 and cos(θμ)>0.3. The total flux integrated νμ charged current single positive pion production cross section on water in the restricted phase space is measured to be ⟨σ⟩ϕ=4.25±0.48(stat)±1.56(syst)×10-40 cm2/nucleon. The total cross section is consistent with the NEUT prediction (5.03×10-40 cm2/nucleon) and 2σ…
“Super p53” Mice Display Retinal Astroglial Changes
2013
Tumour-suppressor genes, such as the p53 gene, produce proteins that inhibit cell division under adverse conditions, as in the case of DNA damage, radiation, hypoxia, or oxidative stress (OS). The p53 gene can arrest proliferation and trigger death by apoptosis subsequent to several factors. In astrocytes, p53 promotes cell-cycle arrest and is involved in oxidative stress-mediated astrocyte cell death. Increasingly, astrocytic p53 is proving fundamental in orchestrating neurodegenerative disease pathogenesis. In terms of ocular disease, p53 may play a role in hypoxia due to ischaemia and may be involved in the retinal response to oxidative stress (OS). We studied the influence of the p53 ge…
Endoscopic surveillance in ulcerative colitis: smart biopsies do it better.
2007
Patients with ulcerative colitis (UC) have a significantly higher risk for the development of colitisassociated colorectal cancer. Endoscopic surveillance is recommended. The growth pattern of dysplastic tissue is often multifocal and flat. Thus, significant lesions might be overlooked. Multiple random biopsies are recommended, but cannot eliminate the possibility of missed cancers with severe consequences for the patient. Chromoendoscopy with methylene blue or indigo carmine can unmask flat lesions and may solve this problem. In addition, confocal laser endomicroscopy enables in vivo histology with subcellular resolution during ongoing colonoscopy and leads to highly selected mucosal biops…
Infarct Size Measurement by Triphenyltetrazolium Chloride StainingVersus In VivoInjection of Propidium Iodide
1997
Infarct size delineation by triphenyltetrazolium chloride (TTC) staining is dependent on sufficient reperfusion. We therefore evaluated the possibility of using propidium iodide (PI), a reagent conventionally used in flow cytometry to fluorescently stain dead cells, for infarct size analysis after short periods of reperfusion. Forty-five rabbits were subjected to either 15 min, 2 h or 4.5 h of coronary artery occlusion without reperfusion, or to 15 min, 30 min and 2 h of coronary artery occlusion followed by 30 min, 1 h and 3 h of reperfusion. Fifteen min before terminating the experiment, PI was injected into the left atrium. Patent blue violet was used to delineate the area at risk. Follo…