Search results for " Left ventricular hypertrophy."

showing 10 items of 20 documents

Association of central and peripheral pulse pressure with intermediate cardiovascular phenoytpes

2012

Objective: We assessed the relationship between pulse pressure and intermediate cardiovascular phenotypes in a middle-aged cohort with high prevalence of hypertension. Background: It has been suggested that central pulse pressure (cPP) is a better predictor of cardiovascular outcome than peripheral pulse pressure (pPP), particularly in the elderly. Yet, it is unclear if cPP provides additional prognostic information to pPP in younger individuals. Methods: In 535 individuals we assessed cPP and pPP as well as the intermediate cardiovascular phenotypes pulse wave velocity (PWV; SphygmoCor, Complior, PulsePen), carotid intima-media thickness (C-IMT; carotid ultrasound), left-ventricular mass i…

MalePhysiologyintermediate cardiovascular phenotypesBlood Pressure030204 cardiovascular system & hematologysurrogate markersCohort Studiespressure0302 clinical medicineHeart Ratepulse wave analysis030212 general & internal medicinerisk-factorsstage renal-diseasePulse wave velocitypulse wave analysiMiddle AgedPhenotypePeripheralPulse pressureleft ventricular hypertrophyarterial stiffnessPhenotypeaortic pressureAortic pressureCardiologyall-cause mortalityFemaleCardiology and Cardiovascular MedicineHumanAdultmedicine.medical_specialtyMean arterial pressurehypertensioncollaborative trial acctpulse wave velocityhypertension; intermediate cardiovascular phenotypes; intimamedia thickness; left ventricular hypertrophy; pressure; pulse wave analysis; pulse wave velocity; Adult; Cohort Studies; Female; Humans; Hypertension; Male; Middle Aged; Phenotype; Blood Pressure; Heart Rate; Internal Medicine; Physiology; Cardiology and Cardiovascular Medicinebrachial blood-pressurewave reflectionsteady component03 medical and health sciencesintermediate cardiovascular phenotypeInternal medicineHeart ratemedicineInternal MedicineHumansintima-media thicknessintimamedia thicknebusiness.industrymedicine.diseaseintimamedia thicknessBlood pressureIntima-media thicknessArterial stiffnessCohort Studiebusiness
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Hypoadiponectinemia, cardiometabolic comorbidities and left ventricular hypertrophy

2014

This study was designed to evaluate the prevalence of cardiometabolic comorbidities and the changes in left ventricular geometry and function in 135 subjects subgrouped according to low or normal total adiponectin plasma (ADPN) levels. Left ventricular (LV) internal diameter/height, total LV mass (LVM) and LVM index (LVMI), relative wall thickness (RWT), LV ejection fraction by echocardiography and diastolic parameters by pulsed-wave Doppler were calculated. Body mass index (BMI) (p < 0.0001), waist-to-hip ratio (p < 0.03), triglycerides (p < 0,001), prevalence of obesity (p < 0.005), visceral obesity (p < 0.003), left ventricular hypertrophy (LVH) (p < 0.001), metabolic syndrome (p < 0.000…

Malemedicine.medical_specialtySettore MED/09 - Medicina InternaDiastoleBlood PressureComorbidityLeft ventricular hypertrophyBody Mass IndexCoronary artery diseaseMetabolic DiseasesInternal medicineInternal MedicinemedicineHumansObesityAgedAged 80 and overEjection fractionAdiponectinbusiness.industrymedicine.diseaseAdiponectin Cardiometabolic comorbidities Left ventricular hypertrophyBlood pressureCardiovascular DiseasesEmergency MedicineCardiologyFemaleHypertrophy Left VentricularAdiponectinMetabolic syndromebusinessBody mass indexMetabolism Inborn Errors
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Association between biomarkers of inflammation and left ventricular hypertrophy in moderate chronic kidney disease.

2007

Aims: Left ventricular hyper- trophy (LVH) is a predictor for cardiovascu- lar mortality, and it is considered to be a surro- gate marker of preclinical cardiovascular dis- ease. This study aimed at evaluating whether fetuin-A plasma levels are decreased in pa- tients with moderate chronic kidney disease (CKD) and their linkage to plasma concentra- tions of hs-C-reactive protein (CRP), cardio- trophyn-1 (CT-1), tumor necrosis factor- (TNF-), propeptide of collagen Type I (PIP) and to LVH. Material and methods: We enrolled 64 moderate CKD and 55 essential hypertensives (EH) with normal renal func- tion as controls. All the patients underwent an echocardiographic examination; plasma sam- ples…

NephrologyAdultMalePhosphopeptidesmedicine.medical_specialtyInflammationEnzyme-Linked Immunosorbent AssayLeft ventricular hypertrophyMuscle hypertrophyinflammation left ventricular hypertrophy chronic kidney diseaseStatistical significanceInternal medicineMedicineHumansMass indexcardiovascular diseasesInflammationAnalysis of Variancebusiness.industryTumor Necrosis Factor-alphaCase-control studyGeneral MedicineMiddle Agedmedicine.diseaseEndocrinologyC-Reactive ProteinNephrologyEchocardiographyCase-Control StudiesCardiologyCytokinesKidney Failure ChronicRegression AnalysisFemaleHypertrophy Left Ventricularalpha-Fetoproteinsmedicine.symptombusinessBiomarkersProcollagenKidney diseaseClinical nephrology
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Frequency of Left Ventricular Hypertrophy in Non-Valvular Atrial Fibrillation

2015

Left ventricular hypertrophy (LVH) is significantly related to adverse clinical outcomes in patients at high risk of cardiovascular events. In patients with atrial fibrillation (AF), data on LVH, that is, prevalence and determinants, are inconsistent mainly because of different definitions and heterogeneity of study populations. We determined echocardiographic-based LVH prevalence and clinical factors independently associated with its development in a prospective cohort of patients with non-valvular (NV) AF. From the "Atrial Fibrillation Registry for Ankle-brachial Index Prevalence Assessment: Collaborative Italian Study" (ARAPACIS) population, 1,184 patients with NVAF (mean age 72 ± 11 yea…

RegistrieMaleCross-sectional studyMyocardial InfarctionLongitudinal StudieLeft ventricular hypertrophyCohort Studiesnon-valvular atrial fibrillationAtrial Fibrillation80 and overPrevalenceechocardiographyMyocardial infarctionLongitudinal StudiesProspective StudiesRegistriesProspective cohort studyUltrasonographyAged 80 and overeducation.field_of_studyMedicine (all)Atrial fibrillationDiabetes MellituMiddle AgedLeft Ventricularleft ventricular hypertrophyItalyHypertensionCardiologyAge Distribution; Aged; Aged 80 and over; Ankle Brachial Index; Atrial Fibrillation; Cohort Studies; Cross-Sectional Studies; Diabetes Mellitus; Female; Humans; Hypertension; Hypertrophy Left Ventricular; Italy; Logistic Models; Longitudinal Studies; Male; Middle Aged; Myocardial Infarction; Peripheral Arterial Disease; Prevalence; Prospective Studies; Ultrasonography; Registries; Cardiology and Cardiovascular Medicine; Medicine (all)Hypertrophy Left VentricularFemaleCardiology and Cardiovascular MedicineHumanmedicine.medical_specialtyLogistic ModelPopulationConcentric hypertrophySocio-culturalenon-valvular atrial fibrillation left ventricular hypertrophy echocardiography cardiovascular diseasesPeripheral Arterial DiseaseAge DistributionInternal medicinemedicineDiabetes MellitusHumansAnkle Brachial Indexcardiovascular diseaseseducationAgedCross-Sectional Studiebusiness.industryAge Distribution; Aged; Aged 80 and over; Ankle Brachial Index; Atrial Fibrillation; Cohort Studies; Cross-Sectional Studies; Diabetes Mellitus; Female; Humans; Hypertension; Hypertrophy Left Ventricular; Italy; Logistic Models; Longitudinal Studies; Male; Middle Aged; Myocardial Infarction; Peripheral Arterial Disease; Prevalence; Prospective Studies; Ultrasonography; Registries; Cardiology and Cardiovascular MedicineOdds ratioHypertrophymedicine.diseasecardiovascular diseasesProspective StudieCross-Sectional StudiesLogistic ModelsCohort StudiebusinessAge Distribution; Aged; Aged 80 and over; Ankle Brachial Index; Atrial Fibrillation; Cohort Studies; Cross-Sectional Studies; Diabetes Mellitus; Female; Humans; Hypertension; Hypertrophy Left Ventricular; Italy; Logistic Models; Longitudinal Studies; Male; Middle Aged; Myocardial Infarction; Peripheral Arterial Disease; Prevalence; Prospective Studies; Ultrasonography; Registries
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Ventricular-vascular coupling in hypertension: methodological considerations and clinical implications.

2014

The present review is addressed to analyse the complex interplay between left ventricle and arterial tree in hypertension. The different methodological approaches to the analysis of ventricular vascular coupling in the time and frequency domain are discussed. Moreover, the role of hypertension-related changes of arterial structure and function (stiffness and wave reflection) on arterial load and how ventricular-vascular coupling modulates the process of left ventricular adaptation to hypertension are analysed.The different interplay between vascular bed and left ventricle emerges as the pathophysiological basis for the development of the multiple patterns of ventricular structural adaptatio…

Ventricular-vascular couplingmedicine.medical_specialtyWave reflectionHeart VentriclesLeftDiastoleBlood PressureLeft ventricular hypertrophyPulse wave analysisVentricular Function LeftInput impedanceVascular StiffnessEffective arterial elastanceInternal medicinemedicineVentricular FunctionHumansArterial stiffness; Effective arterial elastance; Hypertension; Input impedance; Left ventricular hypertrophy; Pulse wave analysis; Therapy; Ventricular-vascular coupling; Wave reflection; Aorta; Arteries; Blood Pressure; Elasticity; Heart Ventricles; Humans; Hypertension; Vascular Stiffness; Ventricular Function Left; Cardiology and Cardiovascular Medicine; Medicine (all)AortaArterial structureVentricular functionbusiness.industryMedicine (all)Left ventricular hypertrophyarterial stiffness effective arterial elastance hypertension input impedance left ventricular hypertrophy pulse wave analysis therapy ventricular–vascular coupling wave reflectionGeneral MedicineArteriesmedicine.diseaseArterial stiffnessSettore MED/11 - Malattie Dell'Apparato CardiovascolareArterial treeElasticitymedicine.anatomical_structureVentricleHypertensionCardiologyTherapybusinessCardiology and Cardiovascular MedicineVentricular vascular couplingJournal of cardiovascular medicine (Hagerstown, Md.)
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Cardiovascular risk assessment beyond Systemic Coronary Risk Estimation: A role for organ damage markers

2012

BACKGROUND: Cardiovascular risk assessment in the clinical practice is mostly based on risk charts, such as Framingham risk score and Systemic Coronary Risk Estimation (SCORE). These enable clinicians to estimate the impact of cardiovascular risk factors and assess individual cardiovascular risk profile. Risk charts, however, do not take into account subclinical organ damage, which exerts independent influence on risk and may amplify the estimated risk profile. Inclusion of organ damage markers in the assessment may thus contribute to improve this process. OBJECTIVE: Our aim was to evaluate the influence of implementation of SCORE charts with widely available indexes of organ damage, with t…

cardiovascular riskmedicine.medical_specialtyestimated glomerular filtration ratemicroalbuminuriaPhysiologyCardiovascular risk organ damage markersCoronary DiseaseLeft ventricular hypertrophyRisk Assessmentmetabolic syndromecardiovascular risk; estimated glomerular filtration rate; left ventricular hypertrophy; metabolic syndrome; microalbuminuria; prevention; score; target organ damagepreventiontarget organ damageSCOREInternal MedicineMedicineHumansAlbuminuriaRisk factorIntensive care medicineEstimationFramingham Risk Scorebusiness.industryMetabolic Syndrome XBiomarkermedicine.diseaseSurgeryleft ventricular hypertrophyAlbuminuriaMicroalbuminuriamedicine.symptomMetabolic syndromebusinessRisk assessmentCardiology and Cardiovascular MedicineBiomarkersGlomerular Filtration RateHuman
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Influence of chronic renal insufficiency on left ventricular diastolic function in hypertensives without left ventricular hypertrophy

2007

chronic renal insufficiencydiastolic function hypertension left ventricular hypertrophy.
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Cardiorenal syndrome type 4: From chronic kidney disease to cardiovascular impairment

2016

Cardiorenal syndrome type 4 (CRS type 4), or chronic renocardiac syndrome, has been defined as "chronic abnormalities in renal function leading to cardiac disease" and recognizes the extreme burden of cardiovascular disease (CVD) risk in patients with chronic kidney disease (CKD). CKD is common and increasingly recognized as a risk factor for CVD. Even though the treatment for CVD has dramatically improved over the past decades, it still takes responsibility for up to 50% of deaths in CKD patients. For this reason, patients with CKD should be thoroughly evaluated for cardiovascular risk factors that require careful management, given the significant burden of CRS type 4 on the healthcare sys…

medicine.medical_specialty030232 urology & nephrologyRenal functionCardiorenal syndromeDisease030204 cardiovascular system & hematologyurologic and male genital diseasesLeft ventricular hypertrophyAtherosclerosis; Cardiorenal syndrome type 4; Cardiovascular risk; Chronic kidney disease; Hypertension; Left ventricular hypertrophy; Atherosclerosis; Cardio-Renal Syndrome; Disease Progression; Humans; Hypertension; Hypertrophy Left Ventricular; Renal Dialysis; Renal Insufficiency Chronic; Risk Factors; Internal Medicine03 medical and health sciences0302 clinical medicineRenal DialysisRisk FactorsInternal medicineChronic kidney diseaseCardiorenal syndrome type 4medicineInternal MedicineHumansIn patientRenal InsufficiencyRenal Insufficiency ChronicRisk factorChronicIntensive care medicineCardio-Renal Syndromebusiness.industryLeft ventricular hypertrophyHypertrophymedicine.diseaseAtherosclerosisCardiovascular riskAtherosclerosis; Cardiorenal syndrome type 4; Cardiovascular riskLeft VentricularRenocardiac SyndromeAtherosclerosiHypertensionCardiologyDisease ProgressionHypertrophy Left VentricularbusinessKidney disease
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Long-term effectiveness of agalsidase alfa enzyme replacement in Fabry disease: A Fabry Outcome Survey analysis

2015

Outcomes from 5 years of treatment with agalsidase alfa enzyme replacement therapy (ERT) for Fabry disease in patients enrolled in the Fabry Outcome Survey (FOS) were compared with published findings for untreated patients with Fabry disease. Data were extracted from FOS, a Shire-sponsored database, for comparison with data from three published studies. Outcomes evaluated were the annualized rate of change in estimated glomerular filtration rate (eGFR) and left ventricular mass indexed to height (LVMI) as well as time to and ages at a composite morbidity endpoint and at death. FOS data were extracted for 740 treated patients who were followed for a median of ~ 5 years. Compared with no trea…

medicine.medical_specialtyEndocrinology Diabetes and MetabolismUrologyCardiomyopathyRenal functionSE Standard errorLeft ventricular hypertrophyBiochemistryLVH Left ventricular hypertrophyLong-term effectivenessEndocrinologyGeneticsMedicineMDRD Modification of Diet in Renal Diseaselcsh:QH301-705.5Molecular BiologyAgalsidase alfaeGFR Estimated glomerular filtration rateFabry diseaselcsh:R5-920CI Confidence intervalbusiness.industryEnzyme replacement therapymedicine.diseaseEgfr Estimated glomerular filtration rateFabry diseaseSurgeryARB Angiotensin receptor blockerSEM Standard error of the meanStandard errorlcsh:Biology (General)SI:TherapyEnzyme replacement therapyCohortFOS Fabry Outcome SurveyLVMI Left ventricular mass indexed to heightlcsh:Medicine (General)businessACEI Angiotensin-converting enzyme inhibitorAgalsidase alfaERT Enzyme replacement therapyMolecular Genetics and Metabolism Reports
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[OP.7B.08] INFLUENCE OF GENDER ON THE RELATIONSHIPS BETWEEN NEW INDICES OF ADIPOSITY AND LEFT VENTRICULAR MASS AND HYPERTROPHY IN HYPERTENSIVE PATIEN…

2016

OBJECTIVE: The unfavourable effects of the association of obesity with hypertension on cardiac structure and function have been extensively studied. However, controversy still exists about the influence of gender on the relationship between obesity and left ventricular mass (LVM) and hypertrophy (LVH). Even if body mass index (BMI) and waist circumference (WC) are widely used as anthropometric predictors for cardiovascular diseases (CVD), their validity has been questioned. Recently, Body Shape Index (ABSI) and Body Roundness Index (BRI) were proposed as alternative measures of adiposity that may better reflect health status (1-2).Our study was aimed to assess the ability of ABSI and BRI in…

medicine.medical_specialtySettore MED/09 - Medicina InternaPhysiologybusiness.industrySettore MED/11 - Malattie Dell'Apparato CardiovascolareMuscle hypertrophyLeft ventricular massEndocrinologyInternal medicineobesity - arterial hypertension - left ventricular hypertrophyInternal MedicinemedicineCardiologyCardiology and Cardiovascular Medicinebusiness
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