Search results for " MS"
showing 10 items of 169 documents
Advances in the analysis of legal and illegal drugs in the aquatic environment
2013
We review the current methods developed for the analysis of legal and illegal drugs (LIDs) and their metabolites in environmental samples. We discuss the advantages and the pitfalls of multi-class methods with emphasis on new strategies for sample preparation and recent technical developments. Finally, we present the applicability of these methods to the analysis of LIDs in protected environmental areas.
Analysis of enniatins and beauvericin by LC-MS/MS in wheat-based products
2017
Due to the matrix complexity for wheat-based products, a comparative study of different rapid extraction procedures was performed for the extraction of enniatins (ENA, ENA1, ENB, ENB1) and beauvericin in flour, pasta, breakfast cereals, and biscuits. Three different approaches were studied during the extraction and purification steps (shaker, Ultra-Turrax, and QuEChERS) for each matrix. Liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) with electrospray source working in a positive mode was used. For the analysis of the five mycotoxins, the three methods were tested in terms of recovery, matrix effect, and sensibility, concluding that Ultra-Turrax extraction was the most …
Forensic comparison of PVC tape backings using time resolved LA-ICP-MS analysis
2019
Abstract Adhesive tapes are common tools for criminal acts such as the construction of improvised explosive devices. Hence, tape samples can be used as evidence to link a suspect to a scene of crime or different crime scenes to each other. A set of 87 black electrical tapes was the subject of a study evaluating a LA-ICP-MS method for the characterization of tape backings regarding their elemental composition in a forensic context. LA-ICP-MS is a powerful tool in forensic investigations due to fast, quasi nondestructive analysis of small samples and detection or determination of elements up to the ultra-trace range. In this study, the development of a semiquantitative LA-ICP-MS method for fo…
DETERMINATION AND ANALYSIS OF HEAD AND CHEST PARAMETERS BY SIMULATION OF VEHICLE-TEENAGER IMPACT
2013
This paper reports the results of multi-body numerical simulation of a vehicle crash with a teenager pedestrian. A previous technique utilized for adult pedestrian impact is applied. The work starts with the determination of the masses for the various segments of the body of a teenager with a total mass of 45 kg and then switches to the construction of the dummy and the middle-class vehicle in the Visual Nastran environment. Simulations are performed for both frontal impacts and lateral impacts, when the vehicle is travelling at a constant speed and when the vehicle is braking, following the Euro NCAP rules on the subject. The results are analysed by calculating the values of the head inju…
An optimal dimensioning method of a green wall structure for noise pollution reduction
2021
International audience; This paper concern the optimization of a multilayered green wall structure including substrate and foliage in order to reduce as much as possible backward noise reflection and forward transmission from the wall. Each component involved in the wall structure is fully characterized experimentally to get its transfer matrix. Simulation demonstrated that foliage layer superimposed to substrate layer doesn’t affect the transmission losses but contributes greatly to the increase of return losses of the green wall structure. To achieve the best performances in terms of return and forward losses as well as frequency bandwidth, the methods of optimization are discussed inclu…
Experimental investigation of the effects of efficiency promoters in a MSF lab-scale unit
2006
Liquid chromatography-mass spectrometry in food safety.
2010
Abstract The use of powerful mass spectrometric detectors in combination with liquid chromatography has played a vital role to solve many problems related to food safety. Since this technique is especially well suited for, but not restricted to the analysis of food contaminants within the food safety area, this review is focused on providing an insight into this field. The basic legislation in different parts of the world is discussed with a focus on the situation within the European Union (EU) and why it favors the use of liquid chromatography–mass spectrometry (LC–MS). Main attention in this review is on the achievements that have been possible because of the latest advances and novelties…
La revisione del palinsesto veronese delle Istituzioni di Gaio e le schede di Bluhme
2014
In the light of unpublished material this paper reconstructs the history of the deciphering of Gaius’ palimpsest of the Capitular Library of Verona (BCapVr, Cod. XV) by Friedrich Bluhme. It deals for the first time with other copies of Bluhme’s transcriptions preserved at the Bonn University Library (ULB, S 675f; ULB, S 1440) and with their relationship to the ones at the Berlin State Library – Prussian Cultural Heritage (SBB-PK, Ms. lat. fol. 308, K. 2, Beil. 2, Fasz. 1).
EFFECT OF DELETERIOUS MUTATION-ACCUMULATION ON THE FITNESS OF RNA BACTERIOPHAGE MS2
2000
RNA viruses show the highest mutation rate in nature. It has been extensively demonstrated that, in the absence of purifying selection, RNA viruses accumulate deleterious mutations at a high rate. However, the parameters describing this accumulation are, in general, poorly understood. The present study reports evidences for fitness declines by the accumulation of deleterious mutations in the bacteriophage MS2. We estimated the rate of fitness decline to be as high as 16% per bottleneck transfer. In addition, our results agree with an additive model of fitness effects.
Rapid evolution of translational control mechanisms in RNA genomes
1997
We have introduced 13 base substitutions into the coat protein gene of RNA bacteriophage MS2. The mutations, which are clustered ahead of the overlapping lysis cistron, do not change the amino acid sequence of the coat protein, but they disrupt a local hairpin, which is needed to control translation of the lysis gene. The mutations decreased the phage titer by four orders of magnitude but, upon passaging, the virus accumulated suppressor mutations that raised the fitness to almost wild-type level. Analysis of the pseudorevertants showed that the disruption of the local hairpin, controlling expression of the lysis gene, had apparently been so complete that its restoration by chance mutations…