Search results for " VAS"
showing 10 items of 1524 documents
A new species of Isatis (Brassicaceae) from the Pollino National Park (Basilicata, S Italy)
2015
A new species, Isatis raimondoi (Brassicaceae) is described from Mt Alpi in the Pollino National Park (Basilicata, Southern Italy). Its relationships with the other species of Isatis occurring in Italy are examined.
Aging Successfully: The Role of Genetics and Environment in the Era of the Aging-Boom. Potential Therapeutic Implications
2019
Aging is one of the main health-related challenges in the world. The average life expectancy of the global population at birth is increasing up to 72 years, in 2016 and it increases about two years every decade. The healthcare costs in many countries are very high because of the increased number of unhealthy populations, and the consequent increase of severe age-related disabilities [1]. Therefore, the goal of the future should be the achievement of the so-called “health-span” (healthy-life-span), more than the treatment of age-related disease to prevent the collapse of the health system. In order to achieve this objective, it is necessary to identify new targets and biomarkers and to addre…
Validation study of the Italian Addenbrooke’s Cognitive Examination Revised in a young-old and old-old population
2011
<i>Aims:</i> The main aims of the study were the translation and the subsequent validation in Italian of the Addenbrooke’s Cognitive Examination Revised (ACE-R), and the evaluation of its usefulness in discriminating cognitively normal subjects from patients with mild dementia in an elderly population. <i>Methods:</i> The ACE-R was translated and adapted into Italian. The Italian ACE-R was administered to a group of 179 elderly subjects (72 cognitively healthy and 107 subjects with mild dementia, mean age 75.4 ± 6.4 years). The group was stratified into two subsamples according to age, i.e. a young-old (<75 years) and an old-old (≧75 years) group, in order to eval…
COMMENTARY TO THE LETTER TO THE EDITOR
2011
mrh.2011.0274 Auteur(s) : Mario Barbagallo mabar@unipa.it, Ligia J Dominguez Geriatric Unit, Dept. of Internal Medicine and Emergent Pathologies, University of Palermo, Italy Correspondence: M. Barbagallo Dear Editor, We thank Dr Kisters for his comments; we agree with the potentiality of magnesium supplementation in the management of hypertension. However, although our data show the effectiveness of magnesium supplementation to improve endothelial vascular function [1], we would be more [...]
Giorgio Vasta, Spaesamento
2012
Si tratta di una recensione multimediale dedicata al romanzo di Giorgio Vasta intitolato "Spaesamento"
GDF15: an emerging modulator of immunity and a strategy in COVID-19 in association with iron metabolism
2021
International audience; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a pandemic of respiratory and cardiovascular diseases, known as coronavirus disease 2019 (COVID-19). SARS-CoV-2 encodes the structural proteins spike (S), envelope (E), membrane (M), and nucleocapsid (N). The receptor-binding domain on the surface subunit S1 is responsible for attachment of the virus to angiotensin (Ang)-converting enzyme 2 (ACE2), which is highly expressed in host cells. The cytokine storm observed in patients with COVID-19 contributes to the endothelial vascular dysfunction, which can lead to acute respiratory distress syndrome, multiorgan failure, alteration in iron homeostasi…
Caratteri biogeografici della flora vascolare della Sicilia
2011
Biogeographia vol. XXX - 2011 (Pubblicato il 23 dicembre 2011) La Biogeografla della Sicilia Caratteri biogeografici della flora Vascolare della Sicilia FRANCESCO M. RAIMONDO, VIVIENNE SPADARO Uniz/ersita di Palermo - Dzjmrtimmto di Biologia Am/aientale e Biodizxersita, via Arc/airafi 38, I—90]23 Palermo (Italy); e—maz'[.-fiancesco. raimondo @am]ga.z't Key words: chorology, endemism, vascular flora, Sicily. SUMMARY According to a recent catalogue and other new contributions, the vascular flora of Sicily consists of more than 3,250 specific and intraspecific taxa. Among them endemic taxa, including those very local and threatened, amount to 16%. Noteworthy are both adventitious and naturaliz…
Considerazioni biogeografiche sulla presenza di specie aliene nella flora vascolare del Mediterraneo
2011
Biogeographia vol. XXX - 2011 (Pubblicato il 23 dicembre 2011) La Biogeografia della Sicilia Considerazioni biogeografiche sulla presenza di specie aliene nella flora Vascolare del Mediterraneo GIANNIANTONIO DOMINA, PIETRO MAZZOLA Dipartimento di Biologia Ameientale e Biodiversita, Universita a’egli Studi di Palermo, via Arc/airafi 38, 90123 Palermo (Italy) Key words: alien vascular flora, islands, Mediterranean, statistics. SUMMARY Relations between the occurrence of aliens and biogeographic Features of some territories in the Mediterranean are analysed. Mediterranean islands host a higher percentage of aliens in comparison with the mainland. The most ‘ important relations have been observed be…
Establishment of a quantitative RT-pCR for detection of vascular cell adhesion molecule-1 transcripts in endothelial cells after stimulation with adv…
1998
Advanced glycation endproducts (AGE) are supposed to increase endothelial expression of adhesion molecules like vascular cell adhesion molecule-1 (VCAM-1) by inducing an intracellular stress with subsequent activation of nuclear transcription factor NF-kappa-B. Quantitative analysis of VCAM-1-transcription has not been demonstrated concerning this topic. Thus, the aim of this study was to establish quantitative reverse transcription polymerase chain reaction (RT-PCR) assays using a spacer gene in order to measure the amounts of specific mRNA for VCAM-1 in human umbilical vein endothelial cells (HUVEC) which were stimulated with AGE-albumin (AGE-BSA). A recombinant RNA-standard was synthesiz…
The influence of advanced glycation endproducts (AGE) on the expression of human endothelial adhesion molecules.
1998
Advanced glycation endproducts (AGEs) possibly play a dominant role in the pathogenesis of macrovascular disease in diabetes. Recent studies could demonstrate that glycated albumin (AGE-BSA) was able to stimulate vascular cell adhesion molecule-1 (VCAM.1) on endothelial cells. The aim of this study was to find out if AGE-BSA was not only able to enhance the expression of vascular cell adhesion molecule-1, but also of intercellular adhesion molecule-1 (ICAM-1) and E-Selectin on human endothelial cells. Stimulation of endothelial cells with AGE-BSA for six hours predominantly increased the expression of VCAM-1, but ICAM-1 and E-Selectin were also upregulated as shown by immunoilluminometric a…