Search results for " concentration"

showing 10 items of 1684 documents

Effect of 3,4-dichloroaniline on the early life stages of the zebrafish (Brachydanio rerio): results of a comparative laboratory study.

1991

An early life-stage (ELS) test was conducted with the zebrafish and 3,4-dichloroaniline (3,4-DCA) in eight laboratories. Based on the results from all eight laboratories, an LOEC of 200 micrograms 3,4-dichloroaniline/liter applies for the early life stages of the zebrafish. Effects observed were reduction of the survival rate and malformations. If the 100 micrograms/liter concentration additionally tested by one laboratory is included in the assessment, an LOEC of 100 micrograms 3,4-DCA/liter is obtained for the survival rate and increase in length. The NOEC is 20 micrograms/liter. The present results of a comparative laboratory study with the zebrafish show that a 42-day ELS test can be co…

AgingAniline CompoundsbiologyHealth Toxicology and MutagenesisPublic Health Environmental and Occupational HealthTemperatureLiterGeneral MedicineHydrogen-Ion Concentrationbiology.organism_classificationPollutionEarly lifeAndrologyToxicologyExperimental animalchemistry.chemical_compoundInvestigation methodsFertilityMulticenter studychemistryAnimalsDichloroanilineZebrafishZebrafishEcotoxicology and environmental safety
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Biological responses of Rhynchophorus ferrugineus (Coleoptera: Curculionidae) to Steinernema carpocapsae (Nematoda: Steinernematidae).

2013

Rhynchophorus ferrugineus (Olivier 1790) (Coleoptera: Curculionidae) is becoming a serious problem in Mediterranean areas where it is well-adapted, and now is present even in the United States (California). The infestations are primarily in urban areas where chemical control is not advisable and million of Euros are spent to control it. The effects of the entomopathogenic nematode Steinernema carpocapsae (Nematoda: Steinernematidae) on mortality, growth, as well as the immune activity of R. ferrugineus larvae, were investigated. R. ferrugineus mortality exhibited a positive trend with the dosage and duration of exposure to S. carpocapsae. The median lethal dose and median lethal time, impor…

AgingImmunity CellularHemocytesNematodaSettore BIO/05 - ZoologiaMicrobial Sensitivity TestsSettore BIO/19 - Microbiologia GeneraleXenorhabdusImmunity HumoralMedian lethal dose median lethal time minimum inhibitory concentration total hemocyte count biological controlSettore AGR/11 - Entomologia Generale E ApplicataLarvaAnimalsWeevilsPest Control BiologicalJournal of economic entomology
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Relationships between oxygen concentration and patterns of energy metabolism in the rotifer Brachionus plicatilis

1992

Abstract 1. 1. Activities of 10 enzymes and accumulation of two metabolites under experimental hypoxia were investigated in the rotifer Brachionus plicatilis . 2. 2. Pyruvate kinase (PK), lactate dehydrogenase (LDH), malic enzyme (ME), phosphoenolpyruvate carboxykinase (PEPCK), malate dehydrogenase (MDH) and fumarase (FUM) activities showed great increase at low oxygen levels. Alcohol dehydrogenase (ADH) activity was not detected. 3. 3. Alanine concentration showed an increase with low oxygen concentrations, while alanine aminotransferase (GTP) showed a slight activity increase with oxygen levels. The high alanine concentration was interpreted as enhanced proteolysis. 4. 4. Our results show…

AlaninebiologyPhysiologyMalic enzymeGeneral MedicineBrachionusbiology.organism_classificationBiochemistryMalate dehydrogenasechemistry.chemical_compoundBiochemistrychemistryLactate dehydrogenasebiology.proteinLimiting oxygen concentrationMolecular BiologyPyruvate kinaseAlcohol dehydrogenaseComparative Biochemistry and Physiology Part B: Comparative Biochemistry
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Phase selection of calcium carbonate through the chirality of adsorbed amino acids.

2007

Alaninechemistry.chemical_classificationModels MolecularAlanineInorganic chemistryStereoisomerismStereoisomerismGeneral ChemistryHydrogen-Ion ConcentrationCatalysislaw.inventionAmino acidCalcium Carbonatechemistry.chemical_compoundCalcium carbonatechemistrylawMicroscopy Electron ScanningAdsorptionHomochiralityCrystallizationAmino AcidsChirality (chemistry)CrystallizationBiomineralizationAngewandte Chemie (International ed. in English)
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New Insight to the Chemistry of Polyaza[n]paracyclophanes. A 15N NMR Study

2001

AldehydesMagnetic Resonance SpectroscopyNitrogen IsotopesChemistryOrganic ChemistryTitrimetryHydrogen-Ion ConcentrationEthers CyclicMetalsCationsAlkanesPolyaminesOrganic chemistryChemistry (relationship)The Journal of Organic Chemistry
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Preferential localization of Lactococcus lactis cells entrapped in a caseinate/alginate phase separated system.

2013

International audience; This study aimed to entrap bioprotective lactic acid bacteria in a sodium caseinate/sodium alginate aqueous two-phase system. Phase diagram at pH = 7 showed that sodium alginate and sodium caseinate were not miscible when their concentrations exceeded 1% (w/w) and 6% (w/w), respectively. The stability of the caseinate/alginate two-phase system was also checked at pH values of 6.0 and 5.5. Lactococcus lactis subsp. lactis LAB3 cells were added in a 4% (w/w) caseinate/1.5% (w/w) alginate two-phase system at pH = 7. Fluorescence microscopy allowed to observe that the caseinate-rich phase formed droplets dispersed in a continuous alginate-rich phase. The distribution of …

Alginates02 engineering and technologyCell SeparationHydrophobic effectchemistry.chemical_compound0404 agricultural biotechnologyColloid and Surface ChemistryGlucuronic AcidPhase (matter)Fluorescence microscope[SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular BiologyPhysical and Theoretical ChemistryAqueous solutionChromatographybiologyHexuronic AcidsLactococcus lactisAqueous two-phase systemCaseins04 agricultural and veterinary sciencesSurfaces and InterfacesGeneral MedicineHydrogen-Ion Concentration021001 nanoscience & nanotechnologybiology.organism_classification040401 food scienceLactic acidPhase diagramLactococcus lactisSodium caseinateBiochemistrychemistryAqueous two-phase system0210 nano-technologySodium alginateBacteriaBacterial cells entrapmentBiotechnologyColloids and surfaces. B, Biointerfaces
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An improved cathode for alkaline fuel cells

2010

Abstract The use of nickel foam as an electrode substrate in alkaline fuel cells (AFCs) has been investigated for bipolar cells incorporating an electrically conducting gas diffusion layer (GDL). Improved performance, compared to a previous design, was obtained by adding an extra active layer (AL) composed of manganese (IV) oxide (MnO2) deposited onto carbon black. This new cathode design performed significantly better (130 mA cm−2 at 0.8 V and 25 °C) than the previous design (35 mA cm−2 under the same condition), especially at higher potential. It has been shown that the GDL is a key component of the gas diffusion electrode for both performance and durability, especially with liquid electr…

Alkaline fuel cellMaterials scienceGas diffusion electrodeRenewable Energy Sustainability and the EnvironmentAnalytical chemistryOxideEnergy Engineering and Power TechnologyElectrolyteCondensed Matter PhysicsCathodelaw.inventionDielectric spectroscopychemistry.chemical_compoundFuel TechnologyChemical engineeringchemistrylawElectrodeLimiting oxygen concentrationInternational Journal of Hydrogen Energy
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Characterization and quantitation of mixtures of alkyl ether sulfates and carboxylic acids by capillary electrophoresis with indirect photometric det…

2003

The separation, characterization, and determination of mixtures of alkyl ether sulfates (AES) and fatty acids (C10-C16) in background electrolytes (BGEs) containing acetonitrile (ACN)-water mixtures is addressed. Due to inhibition of the ionization of the carboxylate groups, the migration time and the resolution between the fatty acids decreased when the water content of the BGE was reduced, but efficiency and resolution between the AES oligomers improved. The migration times increased and resolution improved by substituting 5% ACN by an equivalent amount of dioxane. A complete separation of the two surfactant classes, up to the AES oligomers with 8 ethylene oxide units (EOs) with respect t…

Alkanesulfonateschemistry.chemical_classificationDetection limitMolar concentrationChromatographyEthylene oxideCalibration curveFatty AcidsClinical BiochemistryCarboxylic AcidsElectrophoresis CapillaryBiochemistryOligomerAnalytical ChemistryMolecular WeightSurface-Active Agentschemistry.chemical_compoundCapillary electrophoresischemistryCalibrationSolventsCarboxylateAlkylELECTROPHORESIS
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Synthesis and biological activities of a new class of heat shock protein 90 inhibitors, designed by energy-based pharmacophore virtual screening

2013

The design through energy-based pharmacophore virtual screening has led to aminocyanopyridine derivatives as efficacious new inhibitors of Hsp90. The synthesized compounds showed a good affinity for the Hsp90 ATP binding site in the competitive binding assay. Moreover, they showed an excellent antiproliferative activity against a large number of human tumor cell lines. Further biological studies on the derivative with the higher EC50 confirmed its specific influence on the cellular pathways involving Hsp90.

AminopyridinesInhibitory Concentration 50Structure-Activity RelationshipUser-Computer InterfaceHeat shock proteinCell Line TumorSettore BIO/10 - BiochimicaDrug DiscoveryHumansHSP90 Heat-Shock ProteinsBinding siteVirtual screeningheat shock protein 90 inhibitors energy-based pharmacophore virtual screening cell cycle antiproliferative activitybiologyChemistryHsp90Combinatorial chemistrySettore CHIM/08 - Chimica FarmaceuticaHuman tumorMolecular Docking SimulationCell cultureDrug DesignEnergy basedbiology.proteinMolecular MedicinePharmacophoreDrug Screening Assays Antitumor
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Determination of barbiturates in urine by micellar liquid chromatography and direct injection of sample.

2000

Abstract A liquid chromatographic procedure for the determination of six barbiturates (barbital, diallyl barbituric acid, phenobarbital, butabarbital, amobarbital and pentobarbital) in urine samples is described. The proposed system uses a Spherisorb octadecyl-silane ODS-2 C 18 analytical column and a guard column of similar characteristics. The UV detector was set at 240 nm. A study to select adequate composition of the micellar mobile phase for the separation of these compounds in urine samples is performed. Maximum resolution was achieved with a 0.07 M sodium dodecylsulphate-0.3% propanol at pH 7.4 eluent. Limits of detection at 240 nm were ranged between 0.13 μg ml −1 for diallyl barbit…

AmobarbitalClinical BiochemistryPharmaceutical Science1-PropanolBarbitalAnalytical Chemistrychemistry.chemical_compoundColumn chromatographyDrug DiscoverymedicineHumansSample preparationPentobarbitalSpectroscopyDetection limitBarbituric acidChromatographyButabarbitalHydrogen-Ion ConcentrationchemistryAlkanesulfonic AcidsMicellar liquid chromatographyBarbitalPhenobarbitalBarbituratesCalibrationAmobarbitalmedicine.drugChromatography LiquidJournal of pharmaceutical and biomedical analysis
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