Search results for " electricity"
showing 10 items of 197 documents
Succinobucol’s New Coat — Conjugation with Steroids to Alter Its Drug Effect and Bioavailability
2011
Synthesis, detailed structural characterization (X-ray, NMR, MS, IR, elemental analysis), and studies of toxicity, antioxidant activity and bioavailability of unique potent anti-atherosclerotic succinobucol-steroid conjugates are reported. The conjugates consist of, on one side, the therapeutically important drug succinobucol ([4-{2,6-di-tert-butyl-4-[(1-{[3-tert-butyl-4-hydroxy-5-(propan-2-yl)phenyl]sulfanyl}ethyl)sulfanyl]phenoxy}-4-oxo-butanoic acid]) possessing an antioxidant and anti-inflammatory activity, and on the other side, plant stanol/sterols (stigmastanol, β-sitosterol and stigmasterol) possessing an ability to lower the blood cholesterol level. A cholesterol-succinobucol prodr…
Pricing of electricity futures based on locational price differences : The case of Finland
2018
We find that the pricing of Finnish electricity market futures has been inefficient during the latest 10 years, when the trading volumes of Electricity Price Area Differentials (EPADs) have more than doubled. Even though the calculated futures premium on EPADs is related to some risk measures and the variables capturing the demand and supply conditions in the spot electricity markets, there has been a significant positive excess futures premium in the Finnish market, and financial market participants should have been able to utilize this also in economic terms. This finding is new and relevant for the participants of the Nordic electricity markets also in the future, because both the specul…
High-speed intensified video recordings of sprites and elves over the western Mediterranean Sea during winter thunderstorms
2010
We report the first intensified high‐speed video images of elves, sprites, and halos observed in Europe. All the events corresponded to winter season thunderstorms over the Mediterranean Sea. The observations comprise many elves generated by both cloud‐to‐ground lightning current polarities. In 8 of the 14 sprite observations we observed an elve previous to the sprite. In three cases we observed also an elve quickly followed by a halo and a sprite. In several observations we observed lightning light before the mesospheric transient luminous event. We present a case where the lightning from cloud tops was visible during the entire event. Thanks to the high‐speed videos and their resolution a…
Observationally Weak TGFs in the RHESSI Data
2019
Abstract Terrestrial gamma ray flashes (TGFs) are sub‐millisecond bursts of high energetic gamma radiation associated with intracloud flashes in thunderstorms. In this paper we use the simultaneity of lightning detections by World Wide Lightning Location Network to find TGFs in the Reuven Ramaty High Energy Solar Spectroscopic Imager (RHESSI) data that are too faint to be identified by standard search algorithms. A similar approach has been used in an earlier paper, but here we expand the data set to include all years of RHESSI + World Wide Lightning Location Network data and show that there is a population of observationally weak TGFs all the way down to 0.22 of the RHESSI detection thresh…
Observation of Terrestrial Gamma-Ray Flashes at Mid Latitude
2021
We present a sample of Terrestrial Gamma-ray Flashes (TGFs) observed at mid latitudes by the Atmosphere Space Interaction Monitor (ASIM). The events were detected between June 2018 and August 2020 in the latitude bands between 35° and 51° in both hemispheres, which we hereafter refer to as “mid latitudes.” The sample includes the first observations above urn:x-wiley:2169897X:media:jgrd57293:jgrd57293-math-0001 and consists of 14 events clustered in four geographical regions: north-west Atlantic and eastern USA; Mediterranean Sea; the ocean around South Africa; and north-eastern China and Siberia. We examine the characteristics of each event, both standalone and in the context of the global …
Radio emissions from double RHESSI TGFs
2016
Abstract A detailed analysis of Reuven Ramaty High Energy Solar Spectroscopic Imager (RHESSI) terrestrial gamma ray flashes (TGFs) is performed in association with World Wide Lightning Location Network (WWLLN) sources and very low frequency (VLF) sferics recorded at Duke University. RHESSI clock offset is evaluated and found to experience changes on the 5 August 2005 and 21 October 2013, based on the analysis of TGF‐WWLLN matches. The clock offsets were found for all three periods of observations with standard deviations less than 100 μs. This result opens the possibility for the precise comparative analyses of RHESSI TGFs with the other types of data (WWLLN, radio measurements, etc.) In ca…
Techno-economic evaluation of PV based institutional smart micro-grid under energy pricing dynamics
2020
Abstract The solar photovoltaic (PV) system with battery energy storage have a lot of potential to provide reliable and cost-effective electricity and to contribute in micro-grid operation. However, the operational performance of such type of micro-grid system depends on many factors (e.g. techno-economic sizing, energy management among the sources, market energy prices dynamics, energy dispatch strategies, etc.). In this paper, a typical Indian institutional energy system has considered for techno-economic performance evaluation for operating as a smart micro-grid under market energy pricing dynamics. The institutional energy system has integrated PV, battery storage and DG for operating a…
Design, characterization and in vitro evaluation of 5-aminosalicylic acid loaded N-succinyl-chitosan microparticles for colon specific delivery
2011
The objective of this study was to prepare NS-chitosan microparticles for the delivery of 5-aminosalicylic acid (5-ASA) to the colon. Microparticles can spread out over a large area of colon allowing a more effective local efficacy of 5-ASA. N-Succinyl-chitosan was chosen as carrier system because of its excellent pharmaceutical properties in colon drug targeting such as poor solubility in acid environment, biocompatibility, mucoadhesive properties, and low toxicity. It was prepared by introducing succinic group into chitosan N-terminals of the glucosamine units. 5-ASA loaded NS-chitosan microparticles were prepared using spray-drying. As a control, a matrix obtained by freeze-drying techni…
Molecular Dynamics Simulations of the Initial Adsorption Stages of Fibrinogen on Mica and Graphite Surfaces.
2015
Fibrinogen, a blood glycoprotein of vertebrates, plays an essential role in blood clotting by polymerizing into fibrin when activated. Upon adsorption on material surfaces, it also contributes to determine their biocompatibility and has been implicated in the onset of thrombosis and inflammation at medical implants. Here we present the first fully atomistic simulations of the initial stages of the adsorption process of fibrinogen on mica and graphite surfaces. The simulations reveal a weak adsorption on mica that allows frequent desorption and reorientation events. This adsorption is driven by electrostatic interactions between the protein and the silicate surface as well as the counterion …
Influence of Surface Charge and Polymer Coating on Internalization and Biodistribution of Polyethylene Glycol-Modified Iron Oxide Nanoparticles
2015
International audience; The aim of this study was to investigate the influence of the surface charge and coating of Superparamagnetic Iron Oxide Nanoparticles (SPIONs) on their in vitro and in vivo behaviors. Neutral and negatively-charged PEG-based SPIONs were synthesized and compared to Resovist (R), a carboxydextran-based SPION currently used in clinics. Their cytotoxicity, cell internalization, and potential as contrast agents for magnetic resonance imaging were assessed. Neutral pegylated SPIONs were internalized less readily by the reticuloendothelial system and showed a lower uptake by the liver, compared to negatively-charged SPIONs (with carboxydextran and PEG). These results sugge…