Search results for " essential"
showing 10 items of 219 documents
Bioactive Constituents of Juniperus turbinata Guss. from La Maddalena Archipelago.
2018
A comprehensive phytochemical study of Juniperus turbinata (Cupressaceae) collected from La Maddalena Archipelago (Sardinia, Italy) is reported. Both the essential oil and the ethanolic extract obtained from the aerial parts were analyzed. The essential oil appears to belong to a new chemotype compared to other Mediterranean juniper accessions, as it was favored by geographic isolation of the isles. It showed a low content of monoterpene hydrocarbons and -terpineol, ent-manoyl oxide, 1,10-di-epi-cubenol as the major constituents. The ethanolic fraction contained mainly diterpenoids. Among these, 15-formyloxyimbricatolic acid (7) is a new natural product since it has hitherto been obtained o…
Phytochemical Analysis and Cytotoxicity Towards Multidrug-Resistant Leukemia Cells of Essential Oils Derived from Lebanese Medicinal Plants
2012
Juniperus excelsa fruit essential oil as well as J. oxycedrus, Cedrus libani, and Pinus pinea wood essential oils have been obtained with yields between 2.2 ± 0.3 % to 3.4 ± 0.5 % and analyzed by gas chromatography. Sesquiterpenes mainly characterized C. libani and J. oxycedrus essential oils, while in P. pinea and J. excelsa, monoterpenes were the most abundant compounds. In J. oxycedrus, cis-calamenene (7.8 %), cuparene (3.8 %), and cis-thujopsenal (2.0 %) have been detected for the first time. The cytotoxic activity of these essential oils against drug-sensitive CCRF-CEM and multidrug-resistant P-glycoprotein-expressing CEM/ADR5000 leukemia cells has been investigated (IC₅₀ values: 29.46…
Multilocus Sequence Analysis of the redefined clade Scophthalmi in the genus Vibrio.
2015
A Multilocus Sequence Analysis (MLSA) was performed on members of the Scophthalmi clade in the genus Vibrio, including type and reference strains of the species V. scophthalmi, V. ichthyoenteri, and 39 strains phenotypically identified as Vibrio ichthyoenteri-like, with the aim of better defining boundaries between these two closely related, fish-associated species. The type strain of V. ponticus, recently added to the clade Scophthalmi, was also included. The study was based on partial sequences of the protein-coding housekeeping genes rpoD, mreB, recA, ftsZ, and gyrB, and the 16S rRNA. While the 16S rRNA gene-based trees were unable to pull apart members of V. scophthalmi or V. ichthyoent…
La portada de la iglesia de las Escuelas Pías de Gandía. Su proceso constructivo y modulación arquitectónico-musical
2020
The facade of the church of the Pious Schools of Gandia has not attracted the attention of researchers. However, its conception has a great architectural culture and constitutes an essential work to understand its context, fundamentally, that of the theoretical treatises of the Renaissance. From this study it is wanted to value its architecture and that it is considered as an outstanding ingredient to know its period of construction in general and jesuit architecture in particular. For its understanding, its interpretation in the culture of contemporary architecture treaties and, especially, in the architectural-musical theory of Leon Battista Alberti will be necessary.. La portada de la ig…
Extremal problems of approximation theory in fuzzy context
1999
Abstract The problem of approximation of a fuzzy subset of a normed space is considered. We study the error of approximation, which in this case is characterized by an L -fuzzy number. In order to do this we define the supremum of an L -fuzzy set of real numbers as well as the supremum and the infimum of a crisp set of L -fuzzy numbers. The introduced concepts allow us to investigate the best approximation and the optimal linear approximation. In particular, we consider approximation of a fuzzy subset in the space L p m of differentiable functions in the L q -metric. We prove the fuzzy counterparts of duality theorems, which in crisp case allows effectively to solve extremal problems of the…
Effects of Cucumber mosaic virus and Aster yellows phytoplasma (16SrI-B) on the quality of Echinacea purpurea essential oil.
2011
Echinacea purpurea Moench (L.), known as purple coneflower, is one of the most important medicinal plants, used worldwide for its immunostimulant, bacteriostatic and anti-inflammatory properties, as natural drug and/or food supplement (as infusion). In a previous study carried out in 2002 in Italy to verify possible influence of viral infectious on the plant oil composition, the oil from plants (grown at the Herb Garden of Casola Valsenio, Emilia Romagna region) infected by Cucumber mosaic virus (CMV) was compared to the one from healthy plant by combined gas chromatography mass spectrometry (GC/MS) analyses. Significant quantitative variations in their compositions were verified; the infec…
Standard Essential Patents e licenze a condizioni FRAND nel diritto della UE: equità e ragionevolezza tra antitrust e regolazione
2021
L’articolo affronta la controversa questione della determinazione delle condizioni per la concessione di licenze su brevetti essenziali per l’applicazione di uno standard, evidenziando come si sia rivelata inefficiente la scelta della Commissione UE di affidarla esclusivamente alla privata negoziazione dei termini degli impegni FRAND. Tale sistema ha generato un rilevante contenzioso, spesso affrontato con l’applicazione dell’art. 102 TFUE. Scarso aiuto hanno fornito le indicazioni fornite dalla stessa Commissione con diverse comunicazioni, il cui contenuto viene criticamente esaminato, e la pronuncia della Corte di giustizia sul caso ZTE/Huawei. L’autore è dell’idea che sia venuto il momen…
Delta 5-desaturation of dihomogammalinolenic acid (20:3(n-6)) into arachidonic acid (20:4(n-6)) by rat liver microsomes and incorporation of fatty ac…
1991
Abstract Liver microsomes of rats fed an essential fatty acid (EFA)-deficient diet or a commercial balanced diet were used to study the effect of incubation time on the Δ 5 -desaturation of [ 14 C] dihomogammalinolenic acid (20:3( n −6)) into arachidonic acid (20:4( n −6)) and incorporation of the two acids into microsomal phospholipids. The EFA-deficient diet highly increased the desaturation rate of 20:3( n −6). Incorporation of the formed 20:4( n −6) into microsomal phospholipids was also increased but at saturating concentration of substrate only. At early times of incubation, the precursor 20:3( n −6) was rapidly incorporated into phospholipids. Formation and incorporation of 20:4( n −…
Psychosocial stress, catecholamines, and essential fatty acid metabolism in rats.
1994
To examine the effects of psychosocial stress and the "stress hormone," epinephrine, on essential fatty acid metabolism in rats, two studies were conducted. In the first, the effects of four weeks of (i) social isolation and (ii) group housing (control) on liver microsomal delta 6 and delta 5 n-6 desaturase activity were studied in group-reared male normotensive (Wistar Kyoto) and spontaneously hypertensive (SHR) rats (n = 5/group). The second study examined the effects of acute ip epinephrine (0.0, 1.0, 2.0, and 4.0 mg/kg) 6 hr prior to and following an ig dose (4 g/kg) of safflower oil (rich in 18:2n-6, LA) on plasma and liver LA, 20:4n-6 (AA), and LA/AA ratios in adult essential fatty ac…
Secondary metabolites from Pinus mugo Turra subsp. mugo growing in the Majella National Park (Central Apennines, Italy).
2013
In this study, we examined the composition regarding secondary metabolites of P. mugo Turra ssp. mugo growing in the protected area of Majella National Park, which is the southernmost station of the habitat of this species. Both the nonpolar and polar fractions were considered. In particular, the essential-oil composition showed a high variety of compounds, and 109 compounds were detected, and 101 were identified, among which abietane-type compounds have a taxonomic relevance. Abietanes were also isolated from the polar fraction, together with an acylated flavonol and a remarkably high amount of shikimic acid.