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La Seconda Vita dell'Ambiente Costruito

2021

Il contributo inquadra i saggi, gli studi, le ricerche e progetti pubblicati sul numero 9 di AGATHÓN su ‘La Seconda Vita dell’Ambiente Costruito’, tema di interesse per il mondo accademico, delle professioni e dell’industria. Cambiamenti climatici, eccessivo consumo di suolo e di risorse non rinnovabili, produzione sempre crescente di rifiuti, emergenza pandemica e crisi socio-economica globale sono entrati di fatto nel nostro quotidiano: seppur drammatiche, per certi versi, tali questioni possono essere colte come un’opportunità per ripensare il modo e il mondo in cui viviamo. In questo contesto di ‘rivoluzione’(Floridi, 2020) e di ‘policrisi’ (Losasso, 2020), e con riferimento specifico a…

The contribution frames the essays studies research and projects published in issue 9 of AGATHÓN on ‘The SecondLife of the Built Environment’ an interesting topic for universities businesses and industry. Climate changes excessive use of soil renewable resources ever-increasing production of waste the current pandemic emergency and the global socio-economic crisis have in fact entered our daily life. Even if these are tragic issues they can be somehow seized as an opportunity to rethink the way we live and our world. In this ‘revolutionary’ (Floridi 2020) and ‘polycrisis’ (Losasso 2020) context specifically referring to the building industry the Academy the Research and Industry worlds are called to give answers – based on sustainability and the principles of the Green Deal but also and mostly of the new Bauhaus – that can encourage reconsiderations and re-orientations of processes and products new projects on places buildings objects and materials able to positively affect the governance of the global change that our planet and humanity need able to give a ‘new life’ to the built and/or transformed environment at any scaleSettore ICAR/12 - Tecnologia Dell'Architettura
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Boundedness and compactness of operators related to time-frequency analysis

2018

En esta tesis, estudiamos diferentes aspectos de los operadores relacionados con el análisis tiempo-frecuencia. Cada operador lineal y continuo de la clase de Schwartz en su dual, el espacio de distribuciones temperadas, se puede escribir como un operador integral con núcleo K, o también como un operador integral de Fourier (de hecho, pseudodiferencial). Las diferentes condiciones en el núcleo o el símbolo y la fase (en el caso de los operadores integrales de Fourier) permiten extender el operador a varios espacios de funciones y distribuciones. A continuación detallamos los contenidos de la memoria. En el primer capítulo presentamos la notación, las definiciones de algunos espacios, de suc…

Time-frequency analysisFourier integral operatorsGabor Frames:MATEMÁTICAS::Análisis y análisis funcional [UNESCO]UNESCO::MATEMÁTICAS::Análisis y análisis funcional
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Molecular characterization of an inducible p-coumaric acid decarboxylase from Lactobacillus plantarum: gene cloning, transcriptional analysis, overex…

1997

By using degenerate primers designed from the first 19 N-terminal amino acids of Lactobacillus plantarum p-coumaric acid decarboxylase (PDC), a 56-bp fragment was amplified from L. plantarum in PCRs and used as a probe for screening an L. plantarum genomic bank. Of the 2,880 clones in the genomic bank, one was isolated by colony hybridization and contained a 519-bp open reading frame (pdc gene) followed by a putative terminator structure. The pdc gene is expressed on a monocistronic transcriptional unit, which is transcribed from promoter sequences homologous to Lactococcus promoter sequences. No mRNA from pdc and no PDC activity were detected in uninduced cell extracts, indicating that the…

Transcription GeneticCarboxy-LyasesMolecular Sequence Datamacromolecular substancesMolecular cloningmedicine.disease_causePolymerase Chain ReactionApplied Microbiology and BiotechnologyOpen Reading FramesLactococcusGene expressionEscherichia colimedicineGenomic libraryAmino Acid SequenceCloning MolecularPromoter Regions GeneticEscherichia coliGeneGene LibraryRecombination GeneticElectronic Data ProcessingBase SequenceEcologybiologyNucleic acid sequenceChromosome MappingNucleic Acid Hybridizationhemic and immune systemsGene Expression Regulation BacterialBlotting Northernbiology.organism_classificationMolecular biologyRecombinant ProteinsBlotting SouthernLactobacillusRNA BacterialTerminator (genetics)BiochemistryEnzyme InductionElectrophoresis Polyacrylamide GelLactobacillus plantarumResearch ArticleFood ScienceBiotechnologyApplied and Environmental Microbiology
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TheSCH9 protein kinase mRNA contains a long 5′ leader with a small open reading frame

1993

The SCH9 yeast gene, that was previously identified as a suppressor of cdc25 and ras1- ras2-ts temperature-sensitive mutants, encodes a putative protein kinase that positively regulates the progression of yeast cells through the G1 phase of the cell cycle. We have determined the structure of the SCH9 transcription unit, using primer extension and S1 mapping techniques. The corresponding mRNA included an unusually long 5' region of more than 600 nucleotides preceding the major open reading frame (ORF). While the latter corresponded to a protein of 824 amino acids, an upstream open reading frame (uORF) within the 5' leader could potentially encode a 54 amino acid peptide. To investigate the r…

Transcription GeneticFive prime untranslated regionMolecular Sequence DataSaccharomyces cerevisiaeBioengineeringSaccharomyces cerevisiaeBiologyApplied Microbiology and BiotechnologyBiochemistryOpen Reading FramesGene Expression Regulation FungalUpstream open reading frameGeneticsAmino Acid SequenceRNA MessengerGenes SuppressorAllelesGeneticsMessenger RNABase SequenceG1 PhaseNucleic acid sequenceRNA Fungalbiology.organism_classificationFusion proteinOpen reading frameRegulatory sequenceMutationProtein KinasesBiotechnologyYeast
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The dnaK operon of Streptomyces coelicolor encodes a novel heat-shock protein which binds to the promoter region of the operon

1995

Transcriptional studies have demonstrated that the dnaK gene of Streptomyces coelicolor A3(2) is contained within a 4.3 kb operon. The operon is transcribed from a single (transiently) heat-inducible promoter, dnaKp, that resembles the typical vegetative (sigma 70-recognized) eubacterial consensus promoter sequence. dnaK transcription was found to be heat-inducible at all stages of development in surface-grown cultures. In addition, at the normal growth temperature of 30 degrees C, dnaK transcript levels were shown to vary at different stages of development, being more abundant in young germinating cultures and in mycelium undergoing sporogenesis. The nucleotide sequence of the dnaK operon …

Transcription GeneticOperonMolecular Sequence Datalac operonRepressorMicrobiologytrp operonOpen Reading FramesOperonEscherichia coligal operonHSP70 Heat-Shock ProteinsAmino Acid SequencePromoter Regions GeneticMolecular BiologyHeat-Shock ProteinsGeneticsBinding SitesBase SequenceSequence Homology Amino AcidbiologyEscherichia coli ProteinsStreptomyces coelicolorCell DifferentiationPromoterGene Expression Regulation BacterialBlotting Northernbiology.organism_classificationMolecular biologyRecombinant ProteinsStreptomycesGenes BacterialbacteriaL-arabinose operonHeat-Shock ResponseProtein BindingMolecular Microbiology
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A new glucose-repressible gene identified from the analysis of chromatin structure in deletion mutants of yeast SUC2 locus.

1991

We have previously shown that some changes occur in the chromatin structure of the 3' flank of the yeast SUC2 gene in going from a repressed to an active state. In an attempt to find out the causes of these changes, we have carried out experiments in which mutant copies of SUC2 locus lacking either 5' or 3' flanks have been analysed for their transcriptional activity and chromatin structure. These experiments allowed us to discard any relationship between SUC2 transcription and chromatin changes within its 3'flank. Sequencing of this flank and mRNA analysis, however, resulted in the location of a putative peroxisomal 3-oxoacyl-CoA thiolase gene (POT1), which is repressible by glucose. The d…

Transcription GeneticSaccharomyces cerevisiaeMutantGenes FungalMolecular Sequence DataBioengineeringLocus (genetics)Saccharomyces cerevisiaeApplied Microbiology and BiotechnologyBiochemistryOpen Reading FramesGene Expression Regulation FungalGeneticsAmino Acid SequenceDNA FungalGeneChIA-PETRegulation of gene expressionGeneticsbiologyBase SequenceNucleic acid sequencebiology.organism_classificationAcetyl-CoA C-AcyltransferaseBlotting NorthernChromatinChromatinGlucoseMutagenesisBiotechnologyPlasmidsYeast (Chichester, England)
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Annotation of microsporidian genomes using transcriptional signals

2012

EA GenoSol CT3; International audience; High-quality annotation of microsporidian genomes is essential for understanding the biological processes that govern the development of these parasites. Here we present an improved structural annotation method using transcriptional DNA signals. We apply this method to re-annotate four previously annotated genomes, which allow us to detect annotation errors and identify a significant number of unpredicted genes. We then annotate the newly sequenced genome of Anncaliia algerae. A comparative genomic analysis of A. algerae permits the identification of not only microsporidian core genes, but also potentially highly expressed genes encoding membrane-asso…

Transcription Geneticgenome annotationMESH : Molecular Sequence AnnotationGeneral Physics and AstronomyMESH: PhosphotransferasesGenometranscriptional signalMESH : Protein TransportMESH : Fungal ProteinsDNA FungalConserved SequenceComputingMilieux_MISCELLANEOUSGenetics0303 health sciencesFungal proteinMESH: Conserved SequenceMultidisciplinaryMESH: Genomics030302 biochemistry & molecular biologyGenomicsGenome projectProtein TransportMolecular Sequence Annotation[ SDV.BBM.GTP ] Life Sciences [q-bio]/Biochemistry Molecular Biology/Genomics [q-bio.GN]MESH: Genome FungalMESH: Fungal ProteinsMESH : PhosphotransferasesGenome FungalTransposable elementMESH: Protein TransportGenes FungalGenomicsMESH: Molecular Sequence AnnotationMESH : MicrosporidiaMESH : Open Reading FramesComputational biologyBiologyGeneral Biochemistry Genetics and Molecular BiologyFungal ProteinsOpen Reading Frames03 medical and health sciencesMESH : Conserved Sequence[SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry Molecular Biology/Genomics [q-bio.GN]Anncaliia algeraeparasitic diseasesGene030304 developmental biologybioinformaticMESH: Transcription GeneticMESH : Genome FungalPhosphotransferasesstructural annotationMESH : GenomicsfungiMESH : Transcription GeneticMolecular Sequence AnnotationGeneral ChemistryMESH: Open Reading FramesMESH: MicrosporidiaMESH: DNA FungalmicrosporidiaMESH : Genes Fungal[INFO.INFO-BI]Computer Science [cs]/Bioinformatics [q-bio.QM]MESH : DNA FungalMESH: Genes FungalNature Communications
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Structural and evolutionary analysis of the copia-like elements in the Arabidopsis thaliana genome.

2001

The analysis of 460 kb of genomic sequence of Arabidopsis thaliana chromosome III allowed us to identify two new transposable elements named AtC1 and AtC2. AtC1 shows identical long terminal repeats (LTRs) and all the structural features characteristic of the copia-like active elements. AtC2 is also a full copia-like element, but a putative stop codon in the open reading frame (ORF) would produce a truncated protein. In order to identify the copia-like fraction of the A. thaliana genome, a careful computer-based analysis of the available sequences (which correspond to 92% of the genome) was performed. Approximately 300 nonredundant copia-like sequences homologous to AtC1 and AtC2 were detec…

Transposable elementDatabases FactualArabidopsisSequence HomologyRetrotransposonBiologyGenomeEvolution MolecularMagnoliopsidaOpen Reading FramesGeneticsArabidopsis thalianaAmino Acid SequenceMolecular BiologyEcology Evolution Behavior and SystematicsPhylogenyExpressed Sequence TagsPhylogenetic treeModels GeneticfungiTerminal Repeat SequencesSequence Analysis DNAModels Theoreticalbiology.organism_classificationStop codonLong terminal repeatOpen reading frameGenesEvolutionary biologyDNA Transposable ElementsSequence AlignmentGenome PlantSoftwareMolecular biology and evolution
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Tirant is a new member of the gypsy family of retrotransposons in Drosophila melanogaster.

2000

In this paper, we propose a consensus sequence for a putative complete Tirant retrotransposon. Several defective copies, as well as relevant sequences available in databases have been analyzed. The putative complete Tirant element is 8533 bp long, and presents all the structural features of a retroviruslike transposable element of the gypsy family. It contains three ORFs (open reading frames) that encode putative products resembling the retroviral Gag, Pol, and Env proteins. Southern blot analyses show that complete and defective Tirant elements are widespread in Drosophila melanogaster. The different hybridization patterns observed in several natural populations of this species suggest tha…

Transposable elementRetroelementsvirusesRetrotransposonGenes envOpen Reading FramesPhylogeneticsConsensus SequenceGeneticsConsensus sequenceAnimalsORFSMolecular BiologyPhylogenySouthern blotGeneticsbiologyBase SequenceTerminal Repeat SequencesGeneral Medicinebiology.organism_classificationGenes gagGenes polOpen reading frameDrosophila melanogasterDrosophila melanogasterSequence AlignmentBiotechnologyGenome
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Drosophila melanogaster histone H2B retropseudogene is inserted into a region rich in transposable elements.

1998

We have isolated and characterized the genomic sequence of a Drosophila melanogaster histone H2B pseudogene that is localized outside of the cluster of the replication-dependent histone genes and has all the properties of a retropseudogene. It is highly homologous to the transcribed region of the D. melanogaster histone H2B gene, but not to its flanking regions, and is surrounded by short direct repeats. The pseudogene contains several point mutations that preclude its translation. The sequence of the 3' region of this pseudogene is compatible with the hypothesis that the 3' terminal stem-loop structure of the histone H2B mRNA has served as a primer for the reverse transcription event from …

Transposable elementanimal structuresPseudogeneMolecular Sequence DataLocus (genetics)HistonesOpen Reading FramesGeneticsHistone H2BMelanogasterDirect repeatAnimalsAmino Acid SequenceRNA MessengerMolecular BiologyGeneticsbiologyBase SequenceGeneral MedicineDNAbiology.organism_classificationHistoneDrosophila melanogasterbiology.proteinDNA Transposable ElementsDrosophila melanogasterPseudogenesBiotechnologyGenome
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