Search results for " guida"

French Endocrine Society Guidance on endocrine side effects of immunotherapy.

2018

The management of cancer patients has changed due to the considerably more frequent use of immune checkpoint inhibitors (ICPIs). However, the use of ICPI has a risk of side effects, particularly endocrine toxicity. Since the indications for ICPI are constantly expanding due to their efficacy, it is important that endocrinologists and oncologists know how to look for this type of toxicity and how to treat it when it arises. In view of this, the French Endocrine Society initiated the formulation of a consensus document on ICPI-related endocrine toxicity. In this paper, we will introduce data on the general pathophysiology of endocrine toxicity, and we will then outline expert opinion focusing…

Interactive Guidance Intervention to Address Sustained Social Withdrawal in Preterm Infants in Chile: Protocol for a Randomized Controlled Trial

2020

Background Preterm newborns can be exposed early to significant perinatal stress, and this stress can increase the risk of altered socioemotional development. Sustained social withdrawal in infants is an early indicator of emotional distress which is expressed by low reactivity to the environment, and if persistent, is frequently associated with altered psychological development. Infants born prematurely have a higher probability of developing sustained social withdrawal (adjusted odds ratio 1.84, 95% CI 1.04-3.26) than infants born full term, and there is a correlation between weight at birth and sustained social withdrawal at 12 months of age. Objective The aims of this study are to comp…

Aderenza alle linee guida sulla profilassi antibiotica delle infezioni della ferita chirurgica nel Policlinico Universitario "P. Giaccone" di Palermo

2014

Decreased Proliferation in the Neurogenic Niche, Disorganized Neuroblast Migration, and Increased Oligodendrogenesis in Adult Netrin-5-Deficient Mice.

2020

In the adult mouse brain, neurogenesis mainly occurs in the ventricular-subventricular zone (V-SVZ) and the subgranular zone of the hippocampal dentate gyrus. Neuroblasts generated in the V-SVZ migrate to the olfactory bulb via the rostral migratory stream in response to guidance molecules, such as netrin-1. We previously showed that the related netrin-5 (NTN5) is expressed in Mash1-positive transit-amplifying cells and doublecortin-positive neuroblasts in the granule cell layer of the olfactory bulb, the rostral migratory stream, and the subgranular zone of the adult mouse brain. However, the precise role of NTN5 in adult neurogenesis has not been investigated. In this study, we show that …

: Contextuel influence in choosing curriculum pathways in secondary schools : the school effect.

2004

The results of this research highlight the inequal nature of the process of choosing school careers upper secondary schools according to the school attended by the pupils, notably according to the social background within the school. If important social and academic differences appear in the pupils' study choice, they are mainly ratified by the staff (who tend even sometimes to emphasize them). Thus, the choice appears to be an internal process which come under the policy teach school, which consists in part in managing the social background of the pupils by allocating the later more or less equally between the different tracks available.

: Influence of tenth graders' personal school experiences on their achievement and curriculum choices

2005

This study shows that various dimensions of students' school experiences (namely academic self-evaluation and their attitude towards certain subjects) have a significant influence on their academic achievement (French and Mathematics), as well as on their curriculum choices. The results should encourage teachers and counsellors to take into account students' personal biases when helping them to either construct academic projects or to avoid academic failure.

L'école des filles : Quelle formation pour quels rôles sociaux ? Nouvelle édition revue et actualisée

2004

04071; Si filles et garçons font des scolarités différentes, n'est-ce pas, in fine parce qu'ils sont différents ? Pourtant, les recherches accumulées sur ces questions depuis trente ans convainquent de ce qu'on fait face, non pas à de simples différences, mais bien à de véritables inégalités. Certes des évolutions prennent place, notamment dans la société, qui se répercutent dans l'école. Il fallait donc actualiser "L'école des filles" paru en 1990, et présenter à la fois un bilan actuel de ces inégalités indissociablement scolaires et sociales, et dessiner les tendances qui augurent des évolutions à venir.

Marte Meo as a port of entry to parental sensitivity - a three–case study

2019

Abstract Background Early parent- child relations play an important role in children’s development. Therapeutic intervention towards infants and toddlers at high-risk intends to prevent mental health problems. In this work, the parent-child-dyad is crucial. The video interaction guidance method, Marte Meo, is one among different methods used in attachment-based treatment in an outpatient infant mental health clinic. Parental sensitivity towards infants and toddlers needs is considered significant in developing secure attachment. Secure attachment is further considered decisive for mental health and the extent to which children are at risk of developing mental health problems. Different trea…

The Effects of the Use of Serious Game in Eco-Driving Training

2016

International audience; Serious games present a promising approach to training and learning. The player is engaged in a virtual environment for a purpose beyond pure entertainment, all while having fun. In this paper, we investigate the effects of the use of serious game in eco-driving training. An approach has been developed in order to improve players’ practical skills in terms of eco-driving. This approach is based on the development of a driving simulation based on a serious game, integrating a multisensorial guidance system with metaphors including visual messages (information on fuel consumption, ideal speed area, gearbox management, etc.) and sounds (spatialized sounds, voice message…

Parking Pricing for a Sustainable Transport System

2014

Abstract The purpose of this study has been the develop of a model for designing an efficient parking pricing policy. The aim is an intelligent control and management system of parking pricing integrated with a redefinition of the circulation scheme for a limited traffic zone in the Central Business District (CBD) of Palermo. The transport demand over the entire area of the town has been studied in order to design various parking pricing scenarios with the application of an additional cost on parking inside the selected area of the CBD. This area attracts most of the private vehicular traffic and it is characterized by university faculties, schools, hospitals, offices and commercial areas. …