Search results for " nuclear"

New Acyclic Cytotoxic Jasplakinolide Derivative from the Marine Sponge Jaspis splendens

2019

A new acylic jasplakinolide congener (2), another acyclic derivative requiring revision (4), together with two jasplakinolide derivatives including the parent compound jasplakinolide (1) were isolated from the Indonesian marine sponge Jaspis splendens. The chemical structures of the new and known compounds were unambiguously elucidated based on HRESIMS and exhaustive 1D and 2D NMR spectral analysis as well as a comparison of their NMR data with those of jasplakinolide (1). The isolated jasplakinolides inhibited the growth of mouse lymphoma (L5178Y) cells in vitro with IC50 values in the low micromolar to nanomolar range.

2021

Centaurothamnus maximus (family Asteraceae), is a leafy shrub indigenous to the southwestern Arabian Peninsula. With a paucity of phytochemical data on this species, we set out to chemically characterize the plant. From the aerial parts, two newly identified guaianolides were isolated: 3β-hydroxy-4α(acetoxy)-4β(hydroxymethyl)-8α-(4-hydroxy methacrylate)-1αH,5αH, 6αH-gual-10(14),11(13)-dien-6,12-olide (1) and 15-descarboxy picrolide A (2). Seven previously reported compounds were also isolated: 3β, 4α, 8α-trihydroxy-4-(hydroxymethyl)-lαH, 5αH, 6βH, 7αH-guai-10(14),11(13)-dien-6,12-olide (3), chlorohyssopifolin B (4), cynaropikrin (5), hydroxyjanerin (6), chlorojanerin (7), isorhamnetin (8), …

Evaluation of the shielding in a treatment room with an electronic brachytherapy unit.

2017

Esteya® (Elekta Brachytherapy, Veenendaal, The Netherlands) is an electronic brachytherapy (eBT) system based on a 69.5 kVp x-ray source and a set of collimators of 1 to 3 cm in diameter, used for treating non-melanoma skin cancer lesions. This study aims to estimate room shielding requirements for this unit. The non-primary (scattered and leakage) ambient dose equivalent rates were measured with a Berthold LB-133 monitor (Berthold Technologies, Bad Wildbad, Germany). The latter ranges from 17 mSv h-1 at 0.25 m distance from the x-ray source to 0.1 mSv h-1 at 2.5 m. The necessary room shielding was then estimated following US and some European guidelines. The room shielding for all barriers…

Triterpene saponins of the root bark of Olax obtusifolia De Wild

2018

Abstract Four undescribed triterpenoid saponins together with five known and oleanolic acid were isolated from root bark of Olax obtusifolia De Wild. Their structures were elucidated by spectroscopic methods including 1D and 2D NMR experiments, in combination with mass spectrometry as 3-O-α- l -rhamnopyranosyl-(1→4)-α- l -rhamnopyranosyl-(1→3)-β- d -glucuronopyranosyloleanolic acid, 3-O-α- l -rhamnopyranosyl-(1→4)-α- l -rhamnopyranosyl-(1→3)-β- d -glucuronopyranosyloleanolic acid 28-O-β- d -glucopyranosyl ester, 3-O-α- l -rhamnopyranosyl-(1→3)-β- d -glucopyranosyl-(1→2)-[β- d -glucopyranosyl-(1→3)]-β- d -glucuronopyranosyloleanolic acid and 3-O-α- l -rhamnopyranosyl-(1→3)-β- d -glucopyranos…

Adsorption equilibria of water vapor on cork.

2010

International audience; We report here for the first time a complete thermodynamic study of water vapor adsorption on crude cork powder and plate. Adsorption−desorption isotherms were accurately measured by thermogravimetry at 283, 298, and 313 K in a large range of relative pressure. Adsorption enthalpies were determined by calorimetry as a function of loading. Adsorption−desorption isotherms exhibit a hysteresis due to the swelling of the material. The influence of the presence of lenticels on the adsorption properties of cork is found to be negligible. A detailed analysis and interpretation of adsorption data allow proposal of an adsorption mechanism in two steps. (i) First, water adsorb…

Low-Power, Subthreshold Reference Circuits for the Space Environment : Evaluated with -rays, X-rays, Protons and Heavy Ions

2019

The radiation tolerance of subthreshold reference circuits for space microelectronics is presented. The assessment is supported by measured results of total ionization dose and single event transient radiation-induced effects under &gamma

Transition to turbulence in serpentine pipes

2017

Abstract The geometry considered in the present work (serpentine pipe) is a sequence of U-bends of alternate curvature. It is characterized by pipe diameter, d = 2a and bend diameter, D = 2c. The repeated curvature inversion forces the secondary flow pattern, typical of all flows in curved ducts, to switch between two mirror-like configurations. This causes (i) pressure drop and heat or mass transfer characteristics much different from those occurring either in a straight pipe or in a constant-curvature pipe, and (ii) an early loss of stability of the base steady-state flow. In the present work, four values of the curvature δ = a/c (0.2, 0.3, 0.4 and 0.5) were considered. For each value of …

Experimental Investigation into the Effect of Pyrolysis on Chemical Forms of Heavy Metals in Sewage Sludge Biochar (SSB), with Brief Ecological Risk …

2021

Experimental investigations were carried out to study the effect of pyrolysis temperature on the characteristics, structure and total heavy metal contents of sewage sludge biochar (SSB). The changes in chemical forms of the heavy metals (Zn, Cu, Cr, Ni, Pb and Cd) caused by pyrolysis were analyzed, and the potential ecological risk of heavy metals in biochar (SSB) was evaluated. The conversion of sewage sludge into biochar by pyrolysis reduced the H/C and O/C ratios considerably, resulting in stronger carbonization and a higher degree of aromatic condensation in biochar. Measurement results showed that the pH and specific surface area of biochar increased as the pyrolysis temperature increa…

Optimization of Vehicle-to-Vehicle Frontal Crash Model Based on Measured Data Using Genetic Algorithm

2017

In this paper, a mathematical model for vehicle-to-vehicle frontal crash is developed. The experimental data are taken from the National Highway Traffic Safety Administration. To model the crash scenario, the two vehicles are represented by two masses moving in opposite directions. The front structures of the vehicles are modeled by Kelvin elements, consisting of springs and dampers in parallel, and estimated as piecewise linear functions of displacements and velocities, respectively. To estimate and optimize the model parameters, a genetic algorithm approach is proposed. Finally, it is observed that the developed model can accurately reproduce the real kinematic results from the crash test…

Flow Control of Fluid in Pipelines Using PID Controller

2019

In this paper, a PID controller is utilized in order to control the flow rate of the heavy oil in pipelines by controlling the vibration in a motor pump. A torsional actuator is placed on the motor pump in order to control the vibration on a motor and consequently controlling the flow rates in pipelines. The necessary conditions for the asymptotic stability of the proposed controller are validated by implementing the Lyapunov stability theorem. The theoretical concepts are validated utilizing numerical simulations and analysis, which proves the effectiveness of the PID controller in the control of flow rates in pipelines.