Search results for " response"
showing 10 items of 2127 documents
A methodology for evaluating the flexibility potential of domestic air-conditioning systems
2020
The paper presents a methodology for quantifying the electrical flexibility potential of air-conditioning systems (ACS) installed in residential buildings according to the building envelope characteristics and the ACS performance. In order to provide a thorough analysis of the issue, the ACS baseline consumption referred to the indoor temperature of 24°C has been computed for three typical residential buildings built in the South of Italy over different periods. The baseline consumption was used as a reference to estimate the effect of the set point temperature change on the ACS power profile. The results showed that increasing the set-point temperature of ACS by 2°C and 4°C leads to a redu…
A Fractional-Order Control Approach to Ramp Tracking with Memory-Efficient Implementation
2020
We investigate the fractional-order (FO) control of arbitrary order LTI systems. We show that, for ramp tracking or input disturbance rejection, it is advantageous to include an FO integrator to the open-loop if we have to increase the order of integration further than one. With the lower phase-loss of the FO integrator it is easier to guarantee a desired phase margin. Furthermore the flat phase response around the crossover-frequency (iso-damping property) can be achieved for a wider frequency range such that the closed-loop is more robust wrt. amplitude and phase margins. The drawback of the FO approach is the increased implementation effort and the algebraic decay, which slows down the t…
Enhancing Disaster Response for Hazardous Materials Using Emerging Technologies: The Role of AI and a Research Agenda
2019
Despite all efforts like the introduction of new training methods and personal protective equipment, the need to reduce the number of First Responders (FRs) fatalities and injuries remains. Reports show that advances in technology have not yet resulted in protecting FRs from injuries, health impacts, and odorless toxic gases effectively. Currently, there are emerging technologies that can be exploited and applied in emergency management settings to improve FRs protection. The aim of this paper is threefold: First, to conduct scenario analysis and situations that currently threat the first responders. Second, to conduct gap analysis concerning the new technology needs in relations to the pro…
Dynamic Response of a Rigital Displacement Motor Operating with Various Displacement Strategies
2019
Digital displacement technology has the potential of revolutionizing the performance of hydraulic piston pumps and motors. Instead of connecting each cylinder chamber to high and low pressure in conjunction with the shaft position, two electrically-controlled on/off valves are connected to each chamber. This allows for individual cylinder chamber control. Variable displacement can be achieved by using different displacement strategies, like for example the full stroke, partial stroke, or sequential partial stroke displacement strategy. Each displacement strategy has its transient and steady-state characteristics. This paper provides a detailed simulation analysis of the transient and steady…
Frequency-domain experimental setup for mechatronic and suspension system components
2021
This paper presents a frequency-domain experimental setup for modal analysis of mechatronic and suspension system components. Design, instrumentation and dynamic behavior of the one degree-of-freedom (DOF) system, capable of providing both, periodic and application-specific, excitation forces is described. The excitation is realized by an electromagnetic modal shaker with additional assembly and interface components designed and instrumented for frequency -domain analysis of vertical dynamics. Frequency response functions (FRFs) of the implemented system are experimentally measured and the associated basic model parameters are calculated, correspondingly identified. Accurate fit between the…
Digital Volunteers in Disaster Response: Accessibility Challenges
2019
The emergence of the Digital Humanitarian Volunteer (DHV) movements when disaster strikes have drawn the attention of researchers and practitioners in the emergency management and humanitarian domain. While there are established players in this rapidly developing field, there are still unresolved challenges, including accessibility of their digital tools and platforms. The purposes of this paper are twofold. First, it describes the background, impact and future potential of the DHV movement, and discusses the importance of universal design for the digital tools and platforms used for crowdsourcing of crisis information. Second, this paper shows how lack of concern for universal design and a…
Measuring the quality of humanitarian information products: Insights from the 2015 Nepal earthquake
2018
Information plays a critical role in humanitarian assistance. It has become a product that is shared for multiple purposes such as situational awareness, decision-making, coordination, reporting, and attracting funding. In the aftermath of sudden onset disasters, humanitarians are constrained with huge workload, time pressure, and uncertainties and thus, information products are often criticized with respect to quality issues. In this paper, we aim at developing an empirically grounded framework that can measure the quality of information products through accuracy, objectivity, completeness, and consistency. We validate the framework with the help of practitioners and apply it to the inform…
Immunosuppressive profiles in liquid biopsy at diagnosis predict response to neoadjuvant chemotherapy in triple-negative breast cancer.
2020
Background: Triple-negative breast cancer (TNBC) is characterised by high pathological complete response to neoadjuvant chemotherapy (NAC). However, refractory and poor NAC responders still face very poor outcome, emphasising the urgent need for tools that facilitate identification of these patients, so that surgery or alternatives to NAC are considered early in the treatment protocol. Materials and methods: We combined metabolomics, exosome circulating miRNAs and flow cytometry experimental approaches in TNBC patients at diagnosis with immunohistochemistry in needle biopsy tumours to generate NAC-response predictive models. We also co-cultured and studied crosstalk between isolated patient…
Detecting differences with magnetoencephalography of somatosensory processing after tactile and electrical stimuli.
2018
Abstract Background Deviant stimuli within a standard, frequent stimulus train induce a cortical somatosensory mismatch response (SMMR). The SMMR reflects the brain’s automatic mechanism for the detection of change in a somatosensory domain. It is usually elicited by electrical stimulation, which activates nerve fibers and receptors in superficial and deep skin layers, whereas tactile stimulation is closer to natural stimulation and activates uniform fiber types. We recorded SMMRs after electrical and tactile stimuli. Method 306-channel magnetoencephalography recordings were made with 16 healthy adults under two conditions: electrical (eSMMR) and tactile (tSMMR) stimulations. The SMMR proto…
Cortical network fingerprints predict deep brain stimulation outcome in dystonia.
2018
AbstractBackgroundDeep brain stimulation (DBS) is an effective evidence-based therapy for dystonia. However, no unequivocal predictors of therapy responses exist. We investigate whether patients optimally responding to DBS present distinct brain network organization and structural patterns.MethodsBased on a German multicentre cohort of eighty-two dystonia patients with segmental and generalized dystonia, who received DBS implantation in the globus pallidus internus patients were classified based on the clinical response 36 months after DBS, as superior-outcome group or moderate-outcome group, as above or below 70% motor improvement, respectively. Fifty-one patients met MRI-quality and treat…