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Diagnostic Accuracy of a New Antigen Test for SARS-CoV-2 Detection
2021
Background and aims: Quick and reliable diagnostic tools play an important role in controlling the spread of the SARS-Cov-2 pandemic. The aim of this study was to evaluate the diagnostic accuracy of a new cyto-salivary antigen test aimed at detecting the presence of antigens for SARS-CoV-2, as compared by the gold standard RT-PCR and a lateral flow test. Methods: A total of 433 healthy volunteers were enrolled in the study and the sensitivity and specificity of the new cyto-salivary antigen test were calculated, as compared to the RT-PCR nasopharyngeal swab and to the lateral flow test. Results: A total of 433 samples were collected and tested at the Mediterranean Fair in Palermo from Febru…
Could isotretinoin be a protective agent against COVID-19?: A dermatologist perspective.
2021
Being a "trending" unique treatment for moderate-to-severe acne, isotretinoin (13-cis retinoic acid) (ISO) is currently considered by experts the first line treatment even for mild acne, unless there is an absolute contraindication. ISO was identified, among other retinoids, to inhibit SARS-CoV-2 replication in Vero E6 cells. Shoemark et al.1.
COMEPA (COVID-19 Medicina Policlinico Palermo): a study in hospitalized patients
2021
Coronavirus disease 2019 (COVID-19) has dramatically changed our lives. In the past months, hospitals were saturated of patients; therefore, it is still important to have simple and standardized prognostic factors and to evaluate the efficacy and safety of medications commonly used for COVID-19. We aimed to collect data of the patients hospitalized in Internal Medicine and Geriatrics Wards at the University Hospital (Policlinico) ‘P. Giaccone’ in Palermo, Italy (COMEPA, COVID-19 Medicina Policlinico Palermo), with the main purpose of finding prognostic tools that can be easily used in clinical practice in order to identify patients hospitalized for/with COVID-19 at higher risk of negative o…
Livelli di rappresentazione del testo nell’edizione del De nomine di Orso Beneventano
2018
Viene presentato l’impianto metodologico e tecnologico dell’edizione critica digitale del De nominedi Orso Beneventano (http://www.unipa.it/paolo.monella/ursus), una proof of concept delle innovazioni metodologiche proposte da Tito Orlandi. Il modello qui sperimentato intende superare la dicotomia tra edizione diplomatica e critica grazie ad un ripensamento profondo, semioticamente fondato, dei livelli di trascrizione e di edizione di un testo. I livelli scelti per questa edizione sono: (1) Livello grafematico, le cui unità minime sono i grafemi, inclusi i segni paragrafematici e le brachilogie sistematiche. Tutti i grafemi individuati dall’editore sono elencati nella Graphemic Table of Sig…
Autobiografía y memoria en el diario de viajes del VI Conde de Fernán Núñez = Autobiography and Memory in the Travel Diary of the VI Count of Fernán …
2016
ResumenEl viaje fue una constante en la vida de don Carlos José Gutiérrez de los Ríos, VI conde de Fernán Núñez (1742-1795). A través de ellos pudo cumplir con su servicio al rey y con sus responsabilidades como cabeza del linaje. Asimismo pudo completar su formación y satisfacer anhelos más personales. De todos sus viajes, los realizados dentro y fuera de España, guardó memoria escrita en un diario de viajes, un documento que, en formato manuscrito, se conservó en su archivo familiar. En un periodo cronológico en el que el viaje y su relato adquirieron especial protagonismo, este trabajo analiza el papel que el viaje jugó en la vida y memoria del VI conde de Fernán Núñez y su impronta dent…
El Índice de la Felicidad Nacional Bruta como complemento ante las limitaciones de los modelos socio-económicos tradicionales: El caso del Reino de B…
2018
El siguiente ensayo tiene por objetivo repasar las limitaciones que presentan los modelos socio-económicos tradicionales, como el Producto Interno Bruto per cápita, para medir la calidad de vida y el bienestar en aquellas naciones con concepciones, en la economía y el consumo, distintas a las que se manejan en Occidente y en la economía ortodoxa. Se describirán, en qué sentido, los estudios cualitativos, de carácter subjetivos enfocados principalmente en la felicidad, complementan a los modelos clásicos que se vinieron utilizando en el siglo anterior. En este marco se da cuenta del Índice de Felicidad Nacional Bruta, ideado e implementado en el Reino de Bután, pequeño estado budista locali…
Silmitön ja väkivaltainen : erään mielisairaalapotilaan ura 1900-luvulla
2018
Artikkelissa tarkastellaan yhden pitkäaikaisen potilaan, ”Katrin”, potilaskertomuksen kautta mielisairauteen liitettyjen kriteerien muuttumista, diagnostiikan ja sairastuneiden lääketieteellisen hallinnan kehitystä sekä mielisairaanhoidon muuttumista psykiatriaksi. Artikkelissa kysytään, millä perusteella mielisairaalapotilas lähetettiin hoitolaitokseen, millaisia hoitokäytänteitä häneen sovellettiin ja miksi ja auttoivatko ne. Kysymyksiin vastaamiseen tarvitaan kontekstin, suomalaisen psykiatrian, tuntemista. Katrin yhteenlaskettu hoitoaika piirimielisairaalassa kesti yli 40 vuotta, ja tuo ajanjakso sisältää miltei kaikki 1900-luvulla käytetyt hoitomuodot. Sairauskertomuksen lääketieteelli…
De la fundación de un país al muro fronterizo: una perspectiva social e histórica de la migración en Estados Unidos de Norteamérica
2019
El discurso del actual presidente norteamericano, Donald Trump, que ha reivindicado la construccion de un muro en la frontera de ese pais con Mexico; ha manejado cifras que superaban la estimacion existente de extranjeros no autorizados residiendo en el pais y cuya disputa con el partido democrata llevo al shutdown del gobierno mas extenso de la historia del pais, conducen a pensar que el tema de la inmigracion ilegal en los Estados Unidos es creciente. Sin embargo, esa cifra no solamente no aumento sino que descendio (Warren, 2016), en el marco de un contexto que puede dar cuenta de discriminacion y barreras para la integracion plena de los migrantes. El texto considera brevemente el panor…
Continuous subcutaneous Insulin infusion leads to immediate, table, and long-term changes in metabolic control
2008
Background: Evaluations of continuous subcutaneous insulin infusion (CSII) usually focus on one pre- and one post-CSII measurement to assess metabolic therapy outcome. Aim: Extending this research, the aim of the present study was to provide a more fine-grained analysis of achieved glycaemic control. Methods: In 52 patients with type 1 diabetes (mean age of 37.85 years at CSII begin; s.d. ± 12.41), haemoglobin A1c (HbA1c) levels were assessed every 3 months over a period of 5 years (1 year before and 4 years after the introduction of CSII). Mixed models were utilized to describe changes in glycaemic control. Results: The pre–post course showed that already in the first quarter, a statis…
Fear of COVID-19 as a buffer in the relationship between perceived stress and life satisfaction in the Polish population at the beginning of the glob…
2020
BackgroundCOVID-19 is a significant threat to human life and health. It makes people experience fear, stress, anxiety and mood disor-ders, which have a negative impact on their psychological well-being. The aim of the study was to determine the relation-ship between fear of COVID-19, perceived stress, and life satisfaction during the coronavirus pandemic.Participants and procedure907 Polish people (522 women and 385 men) participated in this study. The Perceived Stress Scale (PSS-10), the Fear of COVID-19 Scale (FOC-6) and the Satisfaction with Life Scale (SWLS) were used in the study.ResultsFear of COVID-19 and perceived stress were positively correlated with each other and both negatively…