Search results for "106"
showing 10 items of 6128 documents
Oligonucleotide-capped nanoporous anodic alumina biosensor as diagnostic tool for rapid and accurate detection of Candida auris in clinical samples.
2021
[EN] Candida auris has arisen as an important multidrug-resistant fungus because of several nosocomial outbreaks and elevated rates of mortality. Accurate and rapid diagnosis of C. auris is highly desired; nevertheless, current methods often present severe limitations and produce misidentification. Herein a sensitive, selective, and time-competitive biosensor based on oligonucleotide-gated nanomaterials for effective detection of C. auris is presented. In the proposed design, a nanoporous anodic alumina scaffold is filled with the fluorescent indicator rhodamine B and the pores blocked with different oligonucleotides capable of specifically recognize C. auris genomic DNA. Gate opening modul…
Deadlock in corporate governance: Finding a common strategy for private telephone companies, 1978–1998
2017
This paper looks at how a group of small, incumbent private telephone companies complied with the international convergence of market structures. The existing research has mainly focused on large national incumbents, assuming a transition to multinational enterprise. This development process is often associated with privatisation policies and various institutional factors. The article tests these assumptions using a case study of the network of Finnish local telephone companies. It looks at the development of an interfirm network, its perspectives on the different phases of the deregulation process, and how the network tried to regenerate itself but failed to form a unified corporate struct…
Towards open access
2019
In accordance with the rotation principle of the Journal, our four-year term for editing the Scandinavian Economic History Review is coming to an end. It is time to pass the Journal on to the capab...
A novel intrinsically disordered outer membrane lipoprotein ofAggregatibacter actinomycetemcomitansbinds various cytokines and plays a role in biofil…
2017
Intrinsically disordered proteins (IDPs) do not have a well-defined and stable 3-dimensional fold. Some IDPs can function as either transient or permanent binders of other proteins and may interact with an array of ligands by adopting different conformations. A novel outer membrane lipoprotein, bacterial interleukin receptor I (BilRI) of the opportunistic oral pathogen Aggregatibacter actinomycetemcomitans binds a key gatekeeper proinflammatory cytokine interleukin (IL)-1b. Because the amino acid sequence of the novel lipoprotein resembles that of fibrinogen binder A of Haemophilus ducreyi, BilRI could have the potential to bind other proteins, such as host matrix proteins. However, from th…
Evolutionary Dynamics of Pathoadaptation Revealed by Three Independent Acquisitions of the VirB/D4 Type IV Secretion System in Bartonella
2017
The α-proteobacterial genus Bartonella comprises a group of ubiquitous mammalian pathogens that are studied as a model for the evolution of bacterial pathogenesis. Vast abundance of two particular phylogenetic lineages of Bartonella had been linked to enhanced host adaptability enabled by lineage-specific acquisition of a VirB/D4 type IV secretion system (T4SS) and parallel evolution of complex effector repertoires. However, the limited availability of genome sequences from one of those lineages as well as other, remote branches of Bartonella has so far hampered comprehensive understanding of how the VirB/D4 T4SS and its effectors called Beps have shaped Bartonella evolution. Here, we repor…
When earwig mothers do not care to share: Parent–offspring competition and the evolution of family life
2017
Kin competition often reduces – and sometimes entirely negates – the benefits of cooperation among family members. Surprisingly, the impact of kin competition on the fitness effects of family life only received close scrutiny in studies on sibling rivalry, whereas the possibility of parent–offspring competition has attracted much less attention. As a consequence, it remains unclear whether and how parent–offspring competition could have affected the early evolution of parental care and family life. Here, we examined the occurrence and consequences of parent–offspring competition over food access in the European earwig Forficula auricularia, an insect with facultative family life reminiscent…
The importance of psychological variables in the perceived exertion of young football players
2017
Las escalas para medir la percepción del esfuerzo están entre los métodos que han sido utilizados para el control y la evaluación de la carga interna del entrenamiento en deportes de equipo como el fútbol. Debido a su naturaleza psicofisiológica, su registro proporciona información proveniente tanto de indicadores fisiológicos como psicológicos del deportista. Dentro del marco de la Teoría de la Autodeterminación (SDT, Self Determination Theory; Deci & Ryan, 1985; Ryan & Deci, 2017) y de la Teoría de las Metas de Logro (AGT, Achievement Goal Theory; Ames, 1992; Nicholls, 1989), en esta tesis doctoral se estudian tanto las variables contextuales desadaptativas (dimensiones del clima motivaci…
La Aceptación Familiar y la Conducta Prosocial: el Rol de los Factores de Personalidad en Menores con Medidas de Internamiento Judicial
2021
espanolEn la presente investigacion se analiza la relacion entre el sentimiento de aceptacion familiar y las distintas dimensiones de la conducta prosocial en menores infractores en regimen de internamiento. El interes esta tambien en determinar el rol mediador y moderador que tienen los factores de personalidad (modelo de los “cinco grandes”) en la relacion entre el sentimiento de aceptacion familiar y la conducta prosocial. La muestra esta formada por 162 menores infractores con edades entre los 14 y los 22 anos (M = 17.10, DT = 1.41), con medida judicial de internamiento en centros de la Comunidad Autonoma de Madrid (Espana). Los resultados obtenidos indican que no hay una relacion direc…
Applying phenomenography in guidance and counselling research
2017
This paper examines phenomenography as a viable qualitative approach in guidance and counselling research. A phenomenographic study maps the qualitatively different ways in which people experience a specific phenomenon and helps researchers to describe the aspects that make one way of experiencing a certain phenomenon qualitatively distinct from another. This paper presents an overview of phenomenographic research, encompassing theoretical, methodological and practical considerations. The application of this approach in guidance and counselling studies is illustrated with examples. peerReviewed
Appraisal of Combined Applications of Trichoderma virens and a Biopolymer-Based Biostimulant on Lettuce Agronomical, Physiological, and Qualitative P…
2020
The current research elucidated the agronomical, physiological, qualitative characteristics and mineral composition of lettuce (Lactuca sativa L. var. longifolia) after treatments with a beneficial fungus Trichoderma virens (TG41) alone or in combination with a vegetal biopolymer-based biostimulant (VBP