Search results for "410"
showing 10 items of 567 documents
Exploration of stationary time-series’ network properties : Visibility-and Horizontal visibility graph of Gaussian white noise, AR (1), MA (1) and AR…
2019
Master's thesis Business Administration BE501 - University of Agder 2019 We haverecordedthe network properties ofstochastic processes’whitenoise,푀퐴(1), 퐴푅(1)and 퐴푅푀퐴(1,1)bymeansof visibility-and horizontal visibility algorithms. The sample series of the stochastic processeswere artificially generated and used in simulationswith multiple repetitions. We examined six global network properties:mean degree, normalized degree centrality, degree distribution, transitivity, assortativity and average geodesic pathtodiscover how theyreflect the structure of the series. These properties were also used to disclose change in behavior due to variation in the series length.Our contribution to the literat…
HBV kapsīdu savākšanās inhibīcija ar mazmolekulāriem savienojumiem
2016
Hepatīta B vīrusa (HBV) infekcija hroniskā formā ir viena no bīstamākajām mūsdienu saslimšanām, tāpēc aktīvi tiek meklētas iedarbīgas zāles infekcijas ārstēšanai. Ar mērķi atrast efektīvu un netoksisku HBV nukleokapsīdu inhibitoru, ir veikta plaši pētīta Bay-41-4109 inhibitora un tā analogu pārbaude zīdītāju šūnās. Šajā darbā HBV kapsīdas proteīna (HBc) sintēze BHK-21 šūnās nodrošināta, izmantojot rekombinantu alfavīrusa replikonu. Ir pārbaudīta Bay-41-4109 un tā analogu citotoksicitāte šūnās. Izmantojot natīvās agarozes un SDS-PAA gēla elektroforēzes un imunoblota metodes tika salīdzināta inhibitoru ietekme uz HBc proteīna ekspresiju un nukleokapsīdu veidošanos šūnās. Atrasts, ka viens no …
Heteroarildihidropirimidīnu ietekmes uz HBV kapsīdu savākšanos pētījumi zīdītāju šūnu kultūrās
2018
Tiek lēsts, ka 257 miljoniem cilvēku ir hroniska Hepatīta B vīrusa (HBV) infekcija un līdzšinējā terapija nevar nodrošināt pilnīgu vīrusa izskaušanu. Darbs veltīts jaunu pretvīrusu savienojumu - kapsīdu savākšanās efektoru - atlasei un raksturošanai zīdītāju šūnu kultūrās. Efektīvai HBV kapsīdas sintēzei šūnās izmantoja rekombinanto alfavīrusa replikonu. Ar natīvās agarozes gela elektroforēzi un imunoblotu tika izvērtēta kapsīdu veidošanās šūnās astoņu jauno savienojumu klātbūtnē. Atrasts, ka četri savienojumi -AS-M-II, AS-M-III, V4-93 un V4-84-s, ietekmē kapsīdu savākšanos. Atlasīto vielu antivīrusa efektu tālāk analizēja HBV producējošās HepG2.2.15 šūnās salīdzinot virionu DNS daudzumu ba…
“Questa donna dal viso netto e gioioso”: Simone de Beauvoir e la stampa italiana
2018
Proseguiamo la riscoperta di Simone de Beauvoir iniziata nel numero precedente: questa volta ripresentiamo due sue interviste dimenticate uscite nel 1959 e nel 1961 sul “Giorno” e su “Paese Sera”.
On Science Museums, Science Capital, and the Public Understanding of Mathematical Modelling
2020
Students’ opportunities to learn informally (e.g. by watching documentaries, visiting museums) explain socio-economic inequities in school performances. To explore informal learning about mathematical modelling, I studied two science museums, as these are environments typically visited by middle-class families. I framed the study by using the notions science capital and the public understanding of mathematical modelling (PUMM) and explored how these are mediated in science museums. The research method entailed observations of displays, artefacts, and visitors. One science museum completely detached mathematics from its use value, whereas the other offered histories of how people used mathem…
Anomaly detection in dynamic systems using weak estimators
2011
Accepted version of an article from the journal: ACM transactions on internet technology. Published version available from the ACM: http://dx.doi.org/10.1145/1993083.1993086 Anomaly detection involves identifying observations that deviate from the normal behavior of a system. One of the ways to achieve this is by identifying the phenomena that characterize “normal” observations. Subsequently, based on the characteristics of data learned from the “normal” observations, new observations are classified as being either “normal” or not. Most state-of-the-art approaches, especially those which belong to the family of parameterized statistical schemes, work under the assumption that the underlying…
Carboxylated-xyloglucan and peptide amphiphile co-assembly in wound healing.
2021
Abstract Hydrogel wound dressings can play critical roles in wound healing protecting the wound from trauma or contamination and providing an ideal environment to support the growth of endogenous cells and promote wound closure. This work presents a self-assembling hydrogel dressing that can assist the wound repair process mimicking the hierarchical structure of skin extracellular matrix. To this aim, the co-assembly behaviour of a carboxylated variant of xyloglucan (CXG) with a peptide amphiphile (PA-H3) has been investigated to generate hierarchical constructs with tuneable molecular composition, structure, and properties. Transmission electron microscopy and circular dichroism at a low c…
State-feedback sampled-data control design for nonlinear systems via passive theory
2013
Published version of an article in the journal: Mathematical Problems in Engineering. Also available from the publisher at: http://dx.doi.org/10.1155/2013/230413 Open Access This paper investigates the problem of passive controller design for a class of nonlinear systems under variable sampling. The Takagi-Sugeno (T-S) fuzzy modeling method is utilized to represent the nonlinear systems. Attention is focused on the design of passive controller for the T-S fuzzy systems via sampled-data control approach. Under the concept of very-strict passivity, a novel time-dependent Lyapunov functional is constructed to develop passive analysis criteria and passive controller synthesis conditions. A new …
Oscillatory Behavior of Second-Order Nonlinear Neutral Differential Equations
2014
Published version of an article in the journal: Abstract and Applied Analysis. Also available from the publisher at: http://dx.doi.org/10.1155/2014/143614 Open Access We study oscillatory behavior of solutions to a class of second-order nonlinear neutral differential equations under the assumptions that allow applications to differential equations with delayed and advanced arguments. New theorems do not need several restrictive assumptions required in related results reported in the literature. Several examples are provided to show that the results obtained are sharp even for second-order ordinary differential equations and improve related contributions to the subject.
Asymptotic Behavior of Higher-Order Quasilinear Neutral Differential Equations
2014
Published version of an article in the journal: Abstract and Applied Analysis. Also available from the publisher at: http://dx.doi.org/10.1155/2014/395368 Open Access We study asymptotic behavior of solutions to a class of higher-order quasilinear neutral differential equations under the assumptions that allow applications to even- and odd-order differential equations with delayed and advanced arguments, as well as to functional differential equations with more complex arguments that may, for instance, alternate indefinitely between delayed and advanced types. New theorems extend a number of results reported in the literature. Illustrative examples are presented.