Search results for "53"
showing 10 items of 2908 documents
Tumor protein 53-induced nuclear protein 1 expression is repressed by miR-155, and its restoration inhibits pancreatic tumor development.
2007
Pancreatic cancer is a disease with an extremely poor prognosis. Tumor protein 53-induced nuclear protein 1 ( TP53INP1 ) is a proapoptotic stress-induced p53 target gene. In this article, we show by immunohistochemical analysis that TP53INP1 expression is dramatically reduced in pancreatic ductal adenocarcinoma (PDAC) and this decrease occurs early during pancreatic cancer development. TP53INP1 reexpression in the pancreatic cancer-derived cell line MiaPaCa2 strongly reduced its capacity to form s.c., i.p., and intrapancreatic tumors in nude mice. This anti-tumoral capacity is, at least in part, due to the induction of caspase 3-mediated apoptosis. In addition, TP53INP1 −/− mouse embryonic…
Observation of a $\gamma$-decaying millisecond isomeric state in $^{128}$Cd$_{80}$
2017
A. Jungclaus et al. -- 6 pags., 5 figs., 2 tabs. -- Open Access funded by Creative Commons Atribution Licence 4.0
The classical two-dimensional Heisenberg model revisited: An $SU(2)$-symmetric tensor network study
2021
The classical Heisenberg model in two spatial dimensions constitutes one of the most paradigmatic spin models, taking an important role in statistical and condensed matter physics to understand magnetism. Still, despite its paradigmatic character and the widely accepted ban of a (continuous) spontaneous symmetry breaking, controversies remain whether the model exhibits a phase transition at finite temperature. Importantly, the model can be interpreted as a lattice discretization of the $O(3)$ non-linear sigma model in $1+1$ dimensions, one of the simplest quantum field theories encompassing crucial features of celebrated higher-dimensional ones (like quantum chromodynamics in $3+1$ dimensio…
Toward a Collective Agenda on AI for Earth Science Data Analysis
2021
In the last years we have witnessed the fields of geosciences and remote sensing and artificial intelligence to become closer. Thanks to both the massive availability of observational data, improved simulations, and algorithmic advances, these disciplines have found common objectives and challenges to advance the modeling and understanding of the Earth system. Despite such great opportunities, we also observed a worrying tendency to remain in disciplinary comfort zones applying recent advances from artificial intelligence on well resolved remote sensing problems. Here we take a position on research directions where we think the interface between these fields will have the most impact and be…
Asymptotic properties of incoherent waves propagating in an all-optical regenerators line
2007
International audience; We present an original method to generate optical pulse trains with random time-interval values from incoherent broadband sources. More precisely, our technique relies on the remarkable properties of a line made of cascaded self-phase modulation-based optical regenerators. Depending on the regenerator parameters, various regimes with noticeably different physical behaviors can be reported.
Arbitrary Phase Access for Stable Fiber Interferometers
2021
Well-controlled yet practical systems that give access to interference effects are critical for established and new functionalities in ultrafast signal processing, quantum photonics, optical coherence characterization, etc. Optical fiber systems constitute a central platform for such technologies. However, harnessing optical interference in a versatile and stable manner remains technologically costly and challenging. Here, degrees of freedom native to optical fibers, i.e., polarization and frequency, are used to demonstrate an easily deployable technique for the retrieval and stabilization of the relative phase in fiber interferometric systems. The scheme gives access (without intricate dev…
Probing the radio emission from air showers with polarization measurements
2014
The emission of radio waves from air showers has been attributed to the so-called geomagnetic emission process. At frequencies around 50 MHz this process leads to coherent radiation which can be observed with rather simple setups. The direction of the electric field induced by this emission process depends only on the local magnetic field vector and on the incoming direction of the air shower. We report on measurements of the electric field vector where, in addition to this geomagnetic component, another component has been observed which cannot be described by the geomagnetic emission process. The data provide strong evidence that the other electric field component is polarized radially wit…
"Table 36" of "Studies of quantum chromodynamics with the ALEPH detector"
1997
Fragmentation distribution for XI(1530) production.
Sosiaalialan asiakastietojärjestelmissä paljon parannettavaa: käyttäjäkokemukset 2019
2020
Sosiaali- ja terveydenhuollon digitalisaatiolle on asetettu paljon odotuksia niin palveluiden laadun, saavutettavuuden kuin tehokkuuden osalta. Asiakas- ja potilastietojärjestelmiltä odotetaan paljon tavoitteiden saavuttamiseksi. Asiakastietojärjestelmät ovat laajasti käytössä sosiaalialalla, mutta niiden käyttöä työvälineenä ja niiden avulla saavutettuja hyötyjä on tutkittu ammattilaisten näkökulmasta vain vähän. Keväällä 2019 kartoitettiin ensimmäistä kertaa valtakunnallisesti sosiaalialan ammattilaisten käyttäjäkokemuksia asiakastietojärjestelmistä. Tässä artikkelissa kuvataan kyselytutkimuksen toteutus ja tulokset eniten käytettyjen tuotemerkkien osalta. Tutkimus toimii pilottina vuonna…
La prestación de maternidad en los supuestos de gestación subrogada
2018
Surrogate pregnancy, as a technique of assisted reproduction prohibited by Spanish law, raises a number of legal questions than, in certain cases, trascend of the Civil Law. Specifically, it has been discussed about de possibility that de person or persons consigner in the gestation contract substitution have access to the provision for maternity benefit. Recently, the Spanish Supreme Court has responded to this issue in the sense of recognizing the right to the provision for maternity benefit to the father or mother ?in fact?, efecttively, develop own parental powers.