Search results for "570"
showing 10 items of 1074 documents
Recuperación de la información científica en pediatría: una oportunidad para el Índice Médico Español
2004
Las bases de datos bibliográficas internacionales (Medline, Embase, Current Contents, etc.) son una de las principales fuentes de información en medicina. Dada la incompleta cobertura de revistas nacionales en estas bases de datos extranjeras, es importante conocer y utilizar también el Índice Médico Español (IME), pues éste incluye la mayor parte de las revistas biomédicas españolas de carácter científico (básicas, experimentales y clínicas), lo cual proporcionará unas reconocidas ventajas para autores y editores en España.Del total de revistas indexadas en algún momento en IME (461 revistas), las relacionadas con la pediatría constituyen el 5,2 % del total (24 revistas) con un total de 21…
Nuevos hitos en la evaluación de la presión arterial en niños y adolescentes
2006
La perspectiva clinica de la presion arterial (PA) en la edad pediatrica ha cambiado en los ultimos anos como consecuencia del mejor conocimiento de los valores de normalidad, que son variables a lo largo del crecimiento y desarrollo y la introduccion sistematica de la medida de PA en los examenes de salud. Con ello se ha podido reconocer su importancia tanto por la deteccion precoz de ninos y adolescentes hipertensos asintomaticos como por su significado como marcador de riesgo de hipertension futura durante la edad adulta1. La sistematizacion de la medida de PA introducida en las recientes guias para la deteccion, evaluacion y tratamiento de la hipertension arterial en ninos y adolescente…
Visualizing a protein quake with time-resolved X-ray scattering at a free-electron laser
2014
We describe a method to measure ultrafast protein structural changes using time-resolved wide-angle X-ray scattering at an X-ray free-electron laser. We demonstrated this approach using multiphoton excitation of the Blastochloris viridis photosynthetic reaction center, observing an ultrafast global conformational change that arises within picoseconds and precedes the propagation of heat through the protein. This provides direct structural evidence for a 'protein quake': the hypothesis that proteins rapidly dissipate energy through quake-like structural motions. peerReviewed
Physical Activity and Motor Competence in Preschool Children
2021
Longitudinal evidence has demonstrated that engagement in physical activity (PA) and the development of motor competence (MC) have numerous tangible health and developmental benefits [...]
Spinovo rozlisena time-of-flight k-reozlisena fotoemissia Ir-- Kompletny fotoemissny experiment.
2017
Ultramicroscopy 183, 19 - 29 (2017). doi:10.1016/j.ultramic.2017.06.025
An energy residual-based approach to gradient effects within the mechanics of generalized continua
2012
AbstractGeneralized continua exhibiting gradient effects are addressed through a method grounded on the energy residual (ER)-based gradient theory by the first author and coworkers. A main tool of this theory is the Clausius-Duhem inequality cast in a form differing from the classical one only by a nonstandard extra term, the (nonlocality) ER, required to satisfy the insulation condition (its global value has to vanish or to take a known value). The ER carries in the nonlocality features of the mechanical problem through a strain-like rate field, being the specific nonlocality source, and a concomitant higher-order long-range stress (or microstress) field. The thermodynamic restrictions on …
Complex chemistry with complex compounds
2016
In recent years gas-phase chemical studies assisted by physical pre-separation allowed for the investigation of fragile single molecular species by gas-phase chromatography. The latest success with the heaviest group 6 transactinide seaborgium is highlighted. The formation of a very volatile hexacarbonyl compound Sg(CO)6 was observed similarly to its lighter homologues molybdenum and tungsten. The interactions of these gaseous carbonyl complex compounds with quartz surfaces were investigated by thermochromatography. Second-generation experiments are under way to investigate the intramolecular bond between the central metal atom of the complexes and the ligands addressing the influence of re…
Search for elements 119 and 120
2020
A search for production of the superheavy elements with atomic numbers 119 and 120 was performed in the 50Ti+249Bk and 50Ti+249Cf fusion-evaporation reactions, respectively, at the gas-filled recoil separator TASCA at GSI Darmstadt, Germany. Over four months of irradiation, the 249Bk target partially decayed into 249Cf, which allowed for a simultaneous search for both elements. Neither was detected at cross-section sensitivity levels of 65 and 200 fb for the 50Ti+249Bk and 50Ti+249Cf reactions, respectively, at a midtarget beam energy of Elab=281.5 MeV. The nonobservation of elements 119 and 120 is discussed within the concept of fusion-evaporation reactions including various theoretical pr…
Fitness Trade-Offs Determine the Role of the Molecular Chaperonin GroEL in Buffering Mutations
2015
Molecular chaperones fold many proteins and their mutated versions in a cell and can sometimes buffer the phenotypic effect of mutations that affect protein folding. Unanswered questions about this buffering include the nature of its mechanism, its influence on the genetic variation of a population, the fitness trade-offs constraining this mechanism, and its role in expediting evolution. Answering these questions is fundamental to understand the contribution of buffering to increase genetic variation and ecological diversification. Here, we performed experimental evolution, genome resequencing, and computational analyses to determine the trade-offs and evolutionary trajectories of Escherich…
A Machine Learning Model to Predict Intravenous Immunoglobulin-Resistant Kawasaki Disease Patients: A Retrospective Study Based on the Chongqing Popu…
2021
Objective: We explored the risk factors for intravenous immunoglobulin (IVIG) resistance in children with Kawasaki disease (KD) and constructed a prediction model based on machine learning algorithms.Methods: A retrospective study including 1,398 KD patients hospitalized in 7 affiliated hospitals of Chongqing Medical University from January 2015 to August 2020 was conducted. All patients were divided into IVIG-responsive and IVIG-resistant groups, which were randomly divided into training and validation sets. The independent risk factors were determined using logistic regression analysis. Logistic regression nomograms, support vector machine (SVM), XGBoost and LightGBM prediction models wer…