Search results for "58"
showing 10 items of 2229 documents
Method Framework for Developing Enterprise Architecture Security Principles
2019
Organizations need to consider many facets of information security in their daily operations – among others, the rapidly increasing use of IT, emerging technologies and digitalization of organizations’ core resources provoke new threats that can be difficult to anticipate. It has been argued that the security and privacy considerations should be embedded in all the areas of organizational activities instead of only relying technical security mechanisms provided by the underlying systems and software. Enterprise Architecture Management (EAM) offers a holistic approach for managing different dimensions of an organization, and can be conceived as a coherent and consistent set of principles tha…
Hospital pedagogy. An unfinished business in the university training of education professionals
2019
La pedagogía hospitalaria se desarrolla donde hay alumnado enfermo, velando por el derecho a la educación de los niños y las niñas. Ello implica que la formación en pedagogía hospitalaria no debe estar dirigida únicamente a los docentes hospitalarios, ya que cualquier docente puede, a lo largo de su carrera profesional, atender en sus aulas a niños/as que enfermen. Este artículo tiene como objetivo reflexionar sobre la necesidad de dicha formación, justificándola a partir de una investigación que ha supuesto el análisis e interpretación de diferentes datos, documentos legislativos y planes de estudio. Para ello, se utiliza una metodología cualitativa, haciendo uso del análisis documental co…
Resentimiento y verdad. Sobre la réplica de Améry a Nietzsche
2004
En su Genealogía de la moral, Nietzsche situó el resentimiento del débil en la base de la moralización de los valores originales del fuerte -entre ellos, la crueldad inherente a la afirmación de la vidaque transformó éstos en negativos. A esta idea del resentimiento como un mecanismo esencialmentedistorsionador se opone Jean Améry, víctima de la violencia nazi, en Más alZa de la culpa y la expiación (1966), donde reivindica su resentimiento hacia los verdugos y sus cómplices como un instrumento de verdad para exigirles el reconocimiento de su crimen y la negación de su condición de verdugos. El objetivo del artículo es reconstruir la trama conceptual en que se articula la divergencia entre …
Age does not affect the efficacy of anti-IL-5/IL-5R in severe asthmatics
2019
Background: Healthcare decisions made on the basis of insufficient evidence may potentially have ineffective or even harmful consequences. The proportion of older ages (over 65 years) in randomized controlled trials (RCTs) for severe asthma is not enough to establish whether anti-IL-5/IL-5R therapies are equally effective in the elderly as in younger subjects. Methods: In order to assess the relationship between age and the efficacy of anti-IL-5 monoclonal antibodies (mABs) with respect to the risk of exacerbations and changes in FEV1, a meta-regression analysis via random-effect method was carried out by plotting the effect estimates (outcome variables) resulting from the pairwise meta-ana…
Therapeutic effects of benralizumab assessed in patients with severe eosinophilic asthma: Real-life evaluation correlated with allergic and non-aller…
2021
Corrado Pelaia,1 Claudia Crimi,2 Alida Benfante,3 Maria Filomena Caiaffa,4 Cecilia Calabrese,5 Giovanna Elisiana Carpagnano,6 Domenico Ciotta Jnr,7 Maria D’Amato,8 Luigi Macchia,9 Santi Nolasco,2 Girolamo Pelaia,1 Simona Pellegrino,7 Nicola Scichilone,3 Giulia Scioscia,10 Giuseppe Spadaro,11 Giuseppe Valenti,12 Alessandro Vatrella,7 Nunzio Crimi2 1Department of Health Sciences, University “Magna Graecia” of Catanzaro, Catanzaro, Italy; 2Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy; 3Department of Biomedicine and Internal and Specialistic Medicine, University of Palermo, Palermo, Italy; 4Allergology and Clinical Immunol…
Severe asthma: One disease and multiple definitions
2021
Abstract Introduction There is, so far, no universal definition of severe asthma. This definition usually relies on: number of exacerbations, inhaled therapy, need for oral corticosteroids, and respiratory function. The use of such parameters varies in the different definitions used. Thus, according to the parameters chosen, each patient may result in having severe asthma or not. The aim of this study was to evaluate how the choice of a specific definition of severe asthma can change the allocation of patients. Methods Data collected from the Severe Asthma Network Italy (SANI) registry were analyzed. All the patients included were then reclassified according to the definitions of U-BIOPRED,…
ARIA‐EAACI care pathways for allergen immunotherapy in respiratory allergy
2021
Funding Information: BSreports personal fees from Allergopharma, during the conduct of the study; grants from National Health Programm, grant, personal fees from Polpharma, ASTRA, personal fees from Mylan, Adamed, patient ombudsman, national Centre for Research and Development, Polish Allergology Society. Funding Information: NGP reports personal fees from Novartis, Nutricia, HAL, MENARINI/FAES FARMA, SANOFI, MYLAN/MEDA, BIOMAY, AstraZeneca, GSK, MSD, ASIT BIOTECH, Boehringer Ingelheim, grants from Gerolymatos International SA, Capricare. Funding Information: CA reports grants from Allergopharma, grants from Idorsia, Swiss National Science Foundation, Christine Kühne‐Center for Allergy Rese…
Overcoming Barriers to the Effective Management of Severe Asthma in Italy.
2021
Pierluigi Paggiaro,1 Simona Barbaglia,2 Stefano Centanni,3,4 Davide Croce,5 Enrico Desideri,6 Saffi Giustini,7,8 Claudio Micheletto,9 Antonino Musarra,10 Nicola Scichilone,11 Ugo Trama,12 Maria Teresa Zedda,7,13 Giorgio Walter Canonica14 1Department of Surgery, Medicine, Molecular Biology, and Critical Care, University of Pisa, Pisa, Italy; 2Associazione Nazionale Pazienti “Respiriamo Insieme”, Padova, Italy; 3Department of Health Sciences, Università degli Studi di Milano, Milan, Italy; 4Respiratory Unit, ASST Santi Paolo e Carlo, Milan, Italy; 5Center for Health Economics, Social and Health Care Management, LIUC-Università Cattaneo, Castellanza, I…
Existence of common zeros for commuting vector fields on 3‐manifolds II. Solving global difficulties
2020
We address the following conjecture about the existence of common zeros for commuting vector fields in dimension three: if $X,Y$ are two $C^1$ commuting vector fields on a $3$-manifold $M$, and $U$ is a relatively compact open such that $X$ does not vanish on the boundary of $U$ and has a non vanishing Poincar\'e-Hopf index in $U$, then $X$ and $Y$ have a common zero inside $U$. We prove this conjecture when $X$ and $Y$ are of class $C^3$ and every periodic orbit of $Y$ along which $X$ and $Y$ are collinear is partially hyperbolic. We also prove the conjecture, still in the $C^3$ setting, assuming that the flow $Y$ leaves invariant a transverse plane field. These results shed new light on t…
Set-valued Brownian motion
2015
Brownian motions, martingales, and Wiener processes are introduced and studied for set valued functions taking values in the subfamily of compact convex subsets of arbitrary Banach space $X$. The present paper is an application of one the paper of the second author in which an embedding result is obtained which considers also the ordered structure of $ck(X)$ and f-algebras.