Search results for "98"
showing 10 items of 1447 documents
Cell therapy of periodontium: from animal to human?
2013
Periodontitis is a chronic inflammatory disease affecting the soft and hard tissues supporting the teeth, which often leads to tooth loss. Its significant impact on the patient's general health and quality of life point to a need for more effective management of this condition. Existing treatments include scaling/root planning and surgical approaches but their overall effects are relatively modest and restricted in application. The goal of regenerative therapy of periodontal defects is to enhance endogenous progenitors and thus promote optimal wound healing. Considering that the host or tissue might be defective in the periodontitis context, it has been proposed that grafting exogenous stem…
Components from the Essential oil of Centaurea aeolica Guss. and C-diluta Aiton from Sicily, Italy
2015
Volatile components from florets, leaves and stems and branches of Centaurea aeolica Guss. harvested in Lipari, Sicily, Italy, were analysed by gas phase chomatography (GC) and gas chomatography mass spectrometry (GC-MS). The main constituents were β-eudesmol, caryophyllene oxide, ( E )-12-norcaryophyll-5-en-2-one and hexahydrofarnesylacetone in flowers, hexahydrofarnesylacetone, 2-methyloctadecane and tricosane in the leaves and hexadecanoic acid , caryophyllene oxide and β-eudesmol in the stems and branches . The analysis of the essential oil of the aerial parts of Centaurea diluta Aiton gave mainly fatty acids and derivatives, the main ones being hexadecanoic acid and (Z,Z)-9,12-octadeca…
Cytotoxicity of Secondary Metabolites from Dracaena viridiflora Engl & Krause and their Semisynthetic Analogues
2017
The MeOH extract of Dracaena viridiflora was found to display significant cytotoxicity against some cancer cell lines. Systematic phytochemical investigation of this extract led to the isolation and structure elucidation of ten secondary metabolites including five spirostane (1-5) and one furostane (6) steroidal saponins. Furthermore, some acetylated spirostane analogues and three previously unreported derivatives with the 22,26-epoxycholesta-5,22-diene skeleton (15-17) were prepared from trillin (1), prosapogenin A of dioscin (2) and dioscin (4) by reaction with ZnCl 2/Ac 2O. Among the isolated and semisynthetic compounds, dioscin showed the most potent cytotoxicity against A549, Jurkat an…
The liquid-argon scintillation pulseshape in DEAP-3600
2020
AbstractDEAP-3600 is a liquid-argon scintillation detector looking for dark matter. Scintillation events in the liquid argon (LAr) are registered by 255 photomultiplier tubes (PMTs), and pulseshape discrimination (PSD) is used to suppress electromagnetic background events. The excellent PSD performance of LAr makes it a viable target for dark matter searches, and the LAr scintillation pulseshape discussed here is the basis of PSD. The observed pulseshape is a combination of LAr scintillation physics with detector effects. We present a model for the pulseshape of electromagnetic background events in the energy region of interest for dark matter searches. The model is composed of (a) LAr scin…
First operation of the KATRIN experiment with tritium
2020
AbstractThe determination of the neutrino mass is one of the major challenges in astroparticle physics today. Direct neutrino mass experiments, based solely on the kinematics of $$\upbeta $$β-decay, provide a largely model-independent probe to the neutrino mass scale. The Karlsruhe Tritium Neutrino (KATRIN) experiment is designed to directly measure the effective electron antineutrino mass with a sensitivity of $$0.2\hbox { eV}$$0.2eV ($$90\%$$90% CL). In this work we report on the first operation of KATRIN with tritium which took place in 2018. During this commissioning phase of the tritium circulation system, excellent agreement of the theoretical prediction with the recorded spectra was …
Material radioassay and selection for the XENON1T dark matter experiment
2017
The XENON1T dark matter experiment aims to detect weakly interacting massive particles (WIMPs) through low-energy interactions with xenon atoms. To detect such a rare event necessitates the use of radiopure materials to minimize the number of background events within the expected WIMP signal region. In this paper we report the results of an extensive material radioassay campaign for the XENON1T experiment. Using gamma-ray spectroscopy and mass spectrometry techniques, systematic measurements of trace radioactive impurities in over one hundred samples within a wide range of materials were performed. The measured activities allowed for stringent selection and placement of materials during the…
Cosmic-ray muon flux at Canfranc Underground Laboratory
2019
Residual flux and angular distribution of high-energy cosmic muons have been measured in two underground locations at the Canfranc Underground Laboratory (LSC) using a dedicated Muon Monitor. The instrument consists of three layers of fast scintillation detector modules operating as 352 independent pixels. The monitor has flux-defining area of 1 m${}^{2}$, covers all azimuth angles, and zenith angles up to $80^\circ$. The measured integrated muon flux is $(5.26 \pm 0.21) \times 10^{-3}$ m${}^{-2}$s${}^{-1}$ in the Hall A of the LAB2400 and $(4.29 \pm 0.17) \times 10^{-3}$ m${}^{-2}$s${}^{-1}$ in LAB2500. The angular dependence is consistent with the known profile and rock density of the sur…
Theia: an advanced optical neutrino detector
2020
The European physical journal. C, Particles and fields 80(5), 416 (2020). doi:10.1140/epjc/s10052-020-7977-8
Minimal coupling in presence of non-metricity and torsion
2020
We deal with the question of what it means to define a minimal coupling prescription in presence of torsion and/or non-metricity, carefully explaining while the naive substitution $\partial\to\na$ introduces extra couplings between the matter fields and the connection that can be regarded as non-minimal in presence of torsion and/or non-metricity. We will also investigate whether minimal coupling prescriptions at the level of the action (MCPL) or at the level of field equations (MCPF) lead to different dynamics. To that end, we will first write the Euler-Lagrange equations for matter fields in terms of the covariant derivatives of a general non-Riemannian space, and derivate the form of the…
Averages of $b$-hadron, $c$-hadron, and $\tau$-lepton properties as of summer 2016
2017
This article reports world averages of measurements of $b$-hadron, $c$-hadron, and $\tau$-lepton properties obtained by the Heavy Flavor Averaging Group using results available through summer 2016. For the averaging, common input parameters used in the various analyses are adjusted (rescaled) to common values, and known correlations are taken into account. The averages include branching fractions, lifetimes, neutral meson mixing parameters, \CP~violation parameters, parameters of semileptonic decays and CKM matrix elements.