Search results for "AEM"

L'harmonisation du droit pharmaceutique en Afrique de l’Ouest : le cas de l’UEMOA

2018

Health protection, the setting up of health security highly depend on an organization of the pharmaceutical market by the establishment of a common pharmaceutical market. In West Africa, particularly within WAEMU, the absence of such of market eases the rise in illicit drug market and impedes a free movement of health products between States. Yet, economic development involves an effective and secured health system. WAEMU’s member States awareness is emerging gradually, hence the necessity to join forces for better health protection ; therefore the long-awaited legal integration can be done through several means ; harmonization, unification, standardization. Harmonization is the means of le…

Hematopoietic stem cell quiescence and function are controlled by the CYLD–TRAF2–p38MAPK pathway

2015

Tesio at al. identify a novel pathway controlled by the tumor suppressor and deubiquitinase cylindromatosis (CYLD), which is involved in the regulation of hematopoietic stem cell quiescence and repopulation potential.

Latest Cretaceous storm-generated sea grass accumulations in the Maastrichtian type area, the Netherlands – preliminary observations

2019

Abstract Ever since the first description of fossil material during the mid-nineteenth century, sea grass has been shown to be quite commonly preserved in ‘pockets’ or ‘clumps’ at certain levels within the Gulpen, Maastricht and Kunrade formations in southern Limburg (the Netherlands) and contiguous areas in northeast Belgium. In those places where silicification occurred during early diagenesis, even completely silicified and three-dimensionally preserved stems and roots can be found, mostly of Thalassocharis bosquetii, in association with fully marine molluscs such as dentaliid scaphopods and a range of larger foraminifera, bivalves, gastropods and ammonites. Such occurrences are best kno…

Review of the Hydrogen Evolution Reaction—A Basic Approach

2021

An increasing emphasis on energy storage has resulted in a surge of R&D efforts into producing catalyst materials for the hydrogen evolution reaction (HER) with emphasis on decreasing the usage of platinum group metals (PGMs). Alkaline water electrolysis holds promise for satisfying future energy storage demands, however the intrinsic potential of this technology is impeded by sluggish reaction kinetics. Here, we summarize the latest efforts within alkaline HER electrocatalyst design, where these efforts are divided between three catalyst design strategies inspired by the three prevailing theories describing the pH-dependence of the HER activity. Modifying the electronic structure of a …

Moringa oleifera Leaf Powder as Functional Additive in Cookies to Protect SH-SY5Y Cells

2021

The aim of this work is the evaluation of the addition of Moringa leaf powder (MLP) in cookies in terms of antioxidant properties, dough processability and sensorial properties of the cookies. The total content of biophenols and flavonoids in MLP was detected and the identification of the bioactive molecules was performed by HPLC-ESI-TOF-MS measurements, before and after oven treatment at 180 ◦C for 20 min. After a preliminary evaluation of the MLP water soluble fraction (MLPsf) cytotoxicity, its protective effect against an oxidative injury induced in the SH-SY5Y cells was assessed. Data evidence that the bioactive molecules present in MLPsf are effective in preventing ROS production and i…

Association between Serum Heat Shock Proteins and Gamma-Delta T Cells—An Outdated Clue or a New Direction in Searching for an Anticancer Strategy? A …

2021

HSPs demonstrate a strong association with gamma-delta (γδ) T cells. Most of the studies regarding interactions between the parameters were conducted in the 1990s. Despite promising results, the concept of targeting γδ T cells by HSPs seems to be a forgotten direction due to potent non-peptidic phosphoantigens rather than HSPs have been found to be the essential stimulatory components for human γδ cells. Currently, with greater knowledge of lymphocyte diversity, and more accurate diagnostic methods, we decided to study the correlation once again in the neoplastic condition. Twenty-one children with newly diagnosed acute lymphoblastic leukaemia (ALL) were enrolled on the study. Serum HSP90 c…

NOTE SUI LIMICOLI SVERNANTI NELLE ZONE UMIDE COSTIERE DELLA PROVINCIA DI TRAPANI

2016

Notes on wintering waders in the coastal humid zones of province of Trapani (Sicily). The coastal wetlands of Trapani still are of great national importance for migratory and wintering waders despite the dramatic reduction occurred in the last hundred years. During this research the author carried out surveys in coastal wetlands from Trapani to Mazara del Vallo, in order to estimate qualitative and accurate quantitative values of wintering waders. The census includes four winters, from 2012-13 to 2015-16 and was carried out in the months of December and January. Noteworthy is the wintering for three consecutive years of the Terek Sandpiper Xenus cinereus, the wintering of Oystercatcher Haem…

Does Neuroprotection Still Have a Role in Injured Brain Following Aneurysmal Subarachnoid Haemorrhage?

2018

TRANSLOCATIONS INVOLVING 5q3 5 MAY ALSO BE ASSOCIATED WITH PLASMA CELL LEUKAEMIA

1990

IMMUNOGENICITY OF AN ACELLULAR PERTUSSIS VACCINE COMPOSED OF GENETICALLY INACTIVATED PERTUSSIS TOXIN COMBINED WITH FILAMENTOUS HEMAGGLUTININ AND PERT…

1993

We studied the immunogenicity of an acellular pertussis vaccine composed of genetically detoxified pertussis toxin (PT-9K/129G), filamentous haemagglutinin, and a 69-kilodalton protein, pertactin, in 30 children aged 12 to 24 months and in 80 infants aged 2 to 4 months. A significant increase of the neutralizing titer and of the titers against pertussis toxin, filamentous hemagglutinin, and pertactin, as determined by enzyme-linked immunosorbent assay, was achieved after three doses of vaccine in all the children; a significant increase of these antibody titers was obtained in 100%, 96.1%, 93.5%, and 98.7% of the infants, respectively.